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The Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation.

Yeates EF, Tesco G.

J Biol Chem. 2016 Jul 22;291(30):15753-66. doi: 10.1074/jbc.M116.718023.


Genetic Deletion of the Clathrin Adaptor GGA3 Reduces Anxiety and Alters GABAergic Transmission.

Walker KR, Modgil A, Albrecht D, Lomoio S, Haydon PG, Moss SJ, Tesco G.

PLoS One. 2016 May 18;11(5):e0155799. doi: 10.1371/journal.pone.0155799.


A small molecule compound IMB-LA inhibits HIV-1 infection by preventing viral Vpu from antagonizing the host restriction factor BST-2.

Mi Z, Ding J, Zhang Q, Zhao J, Ma L, Yu H, Liu Z, Shan G, Li X, Zhou J, Wei T, Zhang L, Guo F, Liang C, Cen S.

Sci Rep. 2015 Dec 16;5:18499. doi: 10.1038/srep18499.


GGA3 mediates TrkA endocytic recycling to promote sustained Akt phosphorylation and cell survival.

Li X, Lavigne P, Lavoie C.

Mol Biol Cell. 2015 Dec 1;26(24):4412-26. doi: 10.1091/mbc.E15-02-0087.


The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1).

von Einem B, Wahler A, Schips T, Serrano-Pozo A, Proepper C, Boeckers TM, Rueck A, Wirth T, Hyman BT, Danzer KM, Thal DR, von Arnim CA.

PLoS One. 2015 Jun 8;10(6):e0129047. doi: 10.1371/journal.pone.0129047.


Helping hands for budding prospects: ENTH/ANTH/VHS accessory proteins in endocytosis, vacuolar transport, and secretion.

Zouhar J, Sauer M.

Plant Cell. 2014 Nov;26(11):4232-44. doi: 10.1105/tpc.114.131680. Review.


The Role of the Transmembrane RING Finger Proteins in Cellular and Organelle Function.

Nakamura N.

Membranes (Basel). 2011 Dec 9;1(4):354-93. doi: 10.3390/membranes1040354.


Quality control: quality control at the plasma membrane: one mechanism does not fit all.

Babst M.

J Cell Biol. 2014 Apr 14;205(1):11-20. doi: 10.1083/jcb.201310113. Review.


The ESCRT machinery: from the plasma membrane to endosomes and back again.

Schuh AL, Audhya A.

Crit Rev Biochem Mol Biol. 2014 May-Jun;49(3):242-61. doi: 10.3109/10409238.2014.881777. Review.


Ubiquitin-dependent sorting in endocytosis.

Piper RC, Dikic I, Lukacs GL.

Cold Spring Harb Perspect Biol. 2014 Jan 1;6(1). pii: a016808. doi: 10.1101/cshperspect.a016808. Review.


Effects of membrane trafficking on signaling by receptor tyrosine kinases.

Miaczynska M.

Cold Spring Harb Perspect Biol. 2013 Nov 1;5(11):a009035. doi: 10.1101/cshperspect.a009035. Review.


Role of adaptor proteins in secretory granule biogenesis and maturation.

Bonnemaison ML, Eipper BA, Mains RE.

Front Endocrinol (Lausanne). 2013 Aug 14;4:101. doi: 10.3389/fendo.2013.00101.


Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease.

Li X, Hong L, Coughlan K, Wang L, Cao L, Tang J.

Acta Biochim Biophys Sin (Shanghai). 2013 Aug;45(8):613-21. doi: 10.1093/abbs/gmt050. Review.


Endocytosis of receptor tyrosine kinases.

Goh LK, Sorkin A.

Cold Spring Harb Perspect Biol. 2013 May 1;5(5):a017459. doi: 10.1101/cshperspect.a017459. Review.


A role for cargo in Arf-dependent adaptor recruitment.

Caster AH, Sztul E, Kahn RA.

J Biol Chem. 2013 May 24;288(21):14788-804. doi: 10.1074/jbc.M113.453621.


BACE1 protein endocytosis and trafficking are differentially regulated by ubiquitination at lysine 501 and the Di-leucine motif in the carboxyl terminus.

Kang EL, Biscaro B, Piazza F, Tesco G.

J Biol Chem. 2012 Dec 14;287(51):42867-80. doi: 10.1074/jbc.M112.407072.


The unique GGA clathrin adaptor of Drosophila melanogaster is not essential.

Luan S, Ilvarsonn AM, Eissenberg JC.

PLoS One. 2012;7(9):e45163. doi: 10.1371/journal.pone.0045163.


Distinct and overlapping roles for AP-1 and GGAs revealed by the "knocksideways" system.

Hirst J, Borner GH, Antrobus R, Peden AA, Hodson NA, Sahlender DA, Robinson MS.

Curr Biol. 2012 Sep 25;22(18):1711-6. doi: 10.1016/j.cub.2012.07.012.


Identification and characterization of antifungal compounds using a Saccharomyces cerevisiae reporter bioassay.

Tebbets B, Stewart D, Lawry S, Nett J, Nantel A, Andes D, Klein BS.

PLoS One. 2012;7(5):e36021. doi: 10.1371/journal.pone.0036021.

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