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Items: 1 to 20 of 92


Alzheimer's disease: The influence of age on clinical heterogeneity through the human brain connectome.

Dickerson BC, Brickhouse M, McGinnis S, Wolk DA.

Alzheimers Dement (Amst). 2016 Dec 22;6:122-135. doi: 10.1016/j.dadm.2016.12.007. eCollection 2017.


Human Central Nervous System (CNS) ApoE Isoforms Are Increased by Age, Differentially Altered by Amyloidosis, and Relative Amounts Reversed in the CNS Compared with Plasma.

Baker-Nigh AT, Mawuenyega KG, Bollinger JG, Ovod V, Kasten T, Franklin EE, Liao F, Jiang H, Holtzman D, Cairns NJ, Morris JC, Bateman RJ.

J Biol Chem. 2016 Dec 30;291(53):27204-27218. doi: 10.1074/jbc.M116.721779. Epub 2016 Oct 28.


The ability of apolipoprotein E fragments to promote intraneuronal accumulation of amyloid beta peptide 42 is both isoform and size-specific.

Dafnis I, Argyri L, Sagnou M, Tzinia A, Tsilibary EC, Stratikos E, Chroni A.

Sci Rep. 2016 Aug 1;6:30654. doi: 10.1038/srep30654.


Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.

Del Prete D, Rice RC, Rajadhyaksha AM, D'Adamio L.

J Biol Chem. 2016 Aug 12;291(33):17209-27. doi: 10.1074/jbc.M116.733626. Epub 2016 Jun 20.


Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders.

Mahley RW.

J Mol Med (Berl). 2016 Jul;94(7):739-46. doi: 10.1007/s00109-016-1427-y. Epub 2016 Jun 9. Review.


Central Nervous System Lipoproteins: ApoE and Regulation of Cholesterol Metabolism.

Mahley RW.

Arterioscler Thromb Vasc Biol. 2016 Jul;36(7):1305-15. doi: 10.1161/ATVBAHA.116.307023. Epub 2016 May 12.


Age, APOE and sex: Triad of risk of Alzheimer's disease.

Riedel BC, Thompson PM, Brinton RD.

J Steroid Biochem Mol Biol. 2016 Jun;160:134-47. doi: 10.1016/j.jsbmb.2016.03.012. Epub 2016 Mar 8. Review.


Visual Receptive Field Properties of Neurons in the Mouse Lateral Geniculate Nucleus.

Tang J, Ardila Jimenez SC, Chakraborty S, Schultz SR.

PLoS One. 2016 Jan 7;11(1):e0146017. doi: 10.1371/journal.pone.0146017. eCollection 2016.


ApoE4-specific Misfolded Intermediate Identified by Molecular Dynamics Simulations.

Williams B 2nd, Convertino M, Das J, Dokholyan NV.

PLoS Comput Biol. 2015 Oct 27;11(10):e1004359. doi: 10.1371/journal.pcbi.1004359. eCollection 2015 Oct.


Association of APOE with tau-tangle pathology with and without β-amyloid.

Farfel JM, Yu L, De Jager PL, Schneider JA, Bennett DA.

Neurobiol Aging. 2016 Jan;37:19-25. doi: 10.1016/j.neurobiolaging.2015.09.011. Epub 2015 Sep 28.


Apolipoprotein E polymorphism is associated with susceptibility to schizophrenia among Saudis.

Al-Asmary SM, Kadasah S, Arfin M, Tariq M, Al-Asmari A.

Arch Med Sci. 2015 Aug 12;11(4):869-76. doi: 10.5114/aoms.2015.53308. Epub 2015 Aug 11.


Oxidized cholesterol as the driving force behind the development of Alzheimer's disease.

Gamba P, Testa G, Gargiulo S, Staurenghi E, Poli G, Leonarduzzi G.

Front Aging Neurosci. 2015 Jun 19;7:119. doi: 10.3389/fnagi.2015.00119. eCollection 2015. Review.


Cerebrospinal Fluid Particles in Alzheimer Disease and Parkinson Disease.

Yang Y, Keene CD, Peskind ER, Galasko DR, Hu SC, Cudaback E, Wilson AM, Li G, Yu CE, Montine KS, Zhang J, Baird GS, Hyman BT, Montine TJ.

J Neuropathol Exp Neurol. 2015 Jul;74(7):672-87. doi: 10.1097/NEN.0000000000000207.


The potential of pathological protein fragmentation in blood-based biomarker development for dementia - with emphasis on Alzheimer's disease.

Inekci D, Jonesco DS, Kennard S, Karsdal MA, Henriksen K.

Front Neurol. 2015 May 11;6:90. doi: 10.3389/fneur.2015.00090. eCollection 2015. Review.


APOEε2 is associated with milder clinical and pathological Alzheimer disease.

Serrano-Pozo A, Qian J, Monsell SE, Betensky RA, Hyman BT.

Ann Neurol. 2015 Jun;77(6):917-29. doi: 10.1002/ana.24369.


Altered Cholesterol Intracellular Trafficking and the Development of Pathological Hallmarks of Sporadic AD.

Chen X, Hui L, Soliman ML, Geiger JD.

J Parkinsons Dis Alzheimers Dis. 2014;1(1). pii: 8.


Apolipoprotein E4 produced in GABAergic interneurons causes learning and memory deficits in mice.

Knoferle J, Yoon SY, Walker D, Leung L, Gillespie AK, Tong LM, Bien-Ly N, Huang Y.

J Neurosci. 2014 Oct 15;34(42):14069-78. doi: 10.1523/JNEUROSCI.2281-14.2014.


Role of PPAR γ in the Differentiation and Function of Neurons.

Quintanilla RA, Utreras E, Cabezas-Opazo FA.

PPAR Res. 2014;2014:768594. doi: 10.1155/2014/768594. Epub 2014 Aug 26. Review.


Apolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases.

Huang Y, Mahley RW.

Neurobiol Dis. 2014 Dec;72 Pt A:3-12. doi: 10.1016/j.nbd.2014.08.025. Epub 2014 Aug 27. Review.


More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration.

Lane-Donovan C, Philips GT, Herz J.

Neuron. 2014 Aug 20;83(4):771-87. doi: 10.1016/j.neuron.2014.08.005. Review.

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