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A Genetic Biomarker of Oxidative Stress, the Paraoxonase-1 Q192R Gene Variant, Associates with Cardiomyopathy in CKD: A Longitudinal Study.

Dounousi E, Bouba I, Spoto B, Pappas K, Tripepi G, Georgiou I, Tselepis A, Elisaf M, Tsakiris D, Zoccali C, Siamopoulos K.

Oxid Med Cell Longev. 2016;2016:1507270. doi: 10.1155/2016/1507270. Epub 2016 May 30.


Profile of the Paraoxonase 1 (PON1) Gene 192Q/R Polymorphism and Clinical Associations among Older Singaporean Chinese with Alzheimer's and Mixed Dementia.

Seow DC, Gao Q, Yap P, Gan JM, Chionh HL, Lim SC, Feng L, Ng TP.

Dement Geriatr Cogn Dis Extra. 2016 Feb 17;6(1):43-54. doi: 10.1159/000442382. eCollection 2016 Jan-Apr.


Paraoxonase-1 and Simvastatin Treatment in Patients with Stable Coronary Artery Disease.

Januszek R.

Int J Vasc Med. 2016;2016:6312478. doi: 10.1155/2016/6312478. Epub 2016 Apr 11.


Antioxidant properties of HDL.

Soran H, Schofield JD, Durrington PN.

Front Pharmacol. 2015 Oct 16;6:222. doi: 10.3389/fphar.2015.00222. eCollection 2015. Review.


Association between Paraoxonase 1 (PON1) Polymorphisms and the Risk of Acute Coronary Syndrome in a North African Population.

Bounafaa A, Berrougui H, Ghalim N, Nasser B, Bagri A, Moujahid A, Ikhlef S, Camponova P, Yamoul N, Simo OK, Essamadi A, Khalil A.

PLoS One. 2015 Aug 4;10(8):e0133719. doi: 10.1371/journal.pone.0133719. eCollection 2015.


Human paraoxonase-1 (PON1): Gene structure and expression, promiscuous activities and multiple physiological roles.

Mackness M, Mackness B.

Gene. 2015 Aug 1;567(1):12-21. doi: 10.1016/j.gene.2015.04.088. Epub 2015 May 9. Review.


Association between genetic polymorphisms and carotid atherosclerosis in patients treated with radiotherapy for nasopharyngeal carcinoma.

Yuan C, Yip SP, Wu VW, Kwong DL, Cheuk IW, Ying M.

Radiat Oncol. 2015 Feb 13;10:39. doi: 10.1186/s13014-015-0341-8.


Large-scale gene-centric analysis identifies polymorphisms for resistant hypertension.

Fontana V, McDonough CW, Gong Y, El Rouby NM, Sá AC, Taylor KD, Chen YD, Gums JG, Chapman AB, Turner ST, Pepine CJ, Johnson JA, Cooper-DeHoff RM.

J Am Heart Assoc. 2014 Nov 10;3(6):e001398. doi: 10.1161/JAHA.114.001398.


The influence of renal function on the association of rs854560 polymorphism of paraoxonase 1 gene with long-term prognosis in patients after myocardial infarction.

Szpakowicz A, Pepinski W, Waszkiewicz E, Maciorkowska D, Skawronska M, Niemcunowicz-Janica A, Dobrzycki S, Musial WJ, Kaminski KA.

Heart Vessels. 2016 Jan;31(1):15-22. doi: 10.1007/s00380-014-0574-8. Epub 2014 Aug 26.


Paraoxonase1, its Q192R polymorphism and HDL-cholesterol in relation to intensive cardiac care unit stay in ischemic heart disease.

Hampe MH, Mogarekar MR.

Indian J Hum Genet. 2014 Jan;20(1):51-8. doi: 10.4103/0971-6866.132756.


Prognostic value of paraoxonase 1 in patients undergoing coronary artery bypass grafting surgery.

Wysocka A, Cybulski M, Berbeć H, Wysokiński A, Stążka J, Zapolski T.

Med Sci Monit. 2014 Apr 11;20:594-600. doi: 10.12659/MSM.890025.


Rare coding variation in paraoxonase-1 is associated with ischemic stroke in the NHLBI Exome Sequencing Project.

Kim DS, Crosslin DR, Auer PL, Suzuki SM, Marsillach J, Burt AA, Gordon AS, Meschia JF, Nalls MA, Worrall BB, Longstreth WT Jr, Gottesman RF, Furlong CE, Peters U, Rich SS, Nickerson DA, Jarvik GP; NHLBI Exome Sequencing Project.

J Lipid Res. 2014 Jun;55(6):1173-8. doi: 10.1194/jlr.P049247. Epub 2014 Apr 7.


Role of PON in anoxia-reoxygenation injury: a Drosophila melanogaster transgenic model.

Caraballo JC, Borcherding J, Rector M, Hornick E, Stoltz D, Zabner J, Comellas AP.

PLoS One. 2014 Jan 6;9(1):e84434. doi: 10.1371/journal.pone.0084434. eCollection 2014.


Association of a polymorphism in PON-1 gene with steroid-induced osteonecrosis of femoral head in Chinese Han population.

Wang Z, Zhang Y, Kong X, Li S, Hu Y, Wang R, Li Y, Lu C, Lin N, Chen W.

Diagn Pathol. 2013 Nov 8;8:186. doi: 10.1186/1746-1596-8-186.


Pharmacogenetics of paraoxonase activity: elucidating the role of high-density lipoprotein in disease.

Kim DS, Marsillach J, Furlong CE, Jarvik GP.

Pharmacogenomics. 2013 Sep;14(12):1495-515. doi: 10.2217/pgs.13.147. Review.


Paraoxonase-1 (PON1) promoter region polymorphisms, serum PON1 status and coronary heart disease.

Mackness B, Turkie W, Mackness M.

Arch Med Sci. 2013 Feb 21;9(1):8-13. doi: 10.5114/aoms.2013.33189. Epub 2013 Feb 10.


Paraoxonase 1 gene polymorphism does not affect clopidogrel response variability but is associated with clinical outcome after PCI.

Park KW, Park JJ, Kang J, Jeon KH, Kang SH, Han JK, Lee SE, Yang HM, Lee HY, Kang HJ, Koo BK, Oh BH, Park YB, Kim HS.

PLoS One. 2013;8(2):e52779. doi: 10.1371/journal.pone.0052779. Epub 2013 Feb 13.


Antioxidant and anti-inflammatory role of paraoxonase 1: implication in arteriosclerosis diseases.

Litvinov D, Mahini H, Garelnabi M.

N Am J Med Sci. 2012 Nov;4(11):523-32. doi: 10.4103/1947-2714.103310.


Paraoxonase 1 (PON1) C/T-108 association with longitudinal mean arterial blood pressure.

Bhatnagar V, Liu L, Nievergelt CM, Richard E, Brophy VH, Pandey B, Lipkowitz MS, O'Connor DT.

Am J Hypertens. 2012 Nov;25(11):1188-94. doi: 10.1038/ajh.2012.106. Epub 2012 Aug 2.

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