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Items: 1 to 20 of 90

1.
2.

Drosophila melanogaster As a Model Organism to Study RNA Toxicity of Repeat Expansion-Associated Neurodegenerative and Neuromuscular Diseases.

Koon AC, Chan HY.

Front Cell Neurosci. 2017 Mar 21;11:70. doi: 10.3389/fncel.2017.00070. eCollection 2017. Review.

3.

Analysis of axonal trafficking via a novel live-imaging technique reveals distinct hedgehog transport kinetics.

Daniele JR, Baqri RM, Kunes S.

Biol Open. 2017 May 15;6(5):714-721. doi: 10.1242/bio.024075.

4.

Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington's disease.

Tanaka M, Ishizuka K, Nekooki-Machida Y, Endo R, Takashima N, Sasaki H, Komi Y, Gathercole A, Huston E, Ishii K, Hui KK, Kurosawa M, Kim SH, Nukina N, Takimoto E, Houslay MD, Sawa A.

J Clin Invest. 2017 Apr 3;127(4):1438-1450. doi: 10.1172/JCI85594. Epub 2017 Mar 6.

5.

Pathogenic Huntington Alters BMP Signaling and Synaptic Growth through Local Disruptions of Endosomal Compartments.

Akbergenova Y, Littleton JT.

J Neurosci. 2017 Mar 22;37(12):3425-3439. doi: 10.1523/JNEUROSCI.2752-16.2017. Epub 2017 Feb 24.

PMID:
28235896
6.

Investigating Mutations to Reduce Huntingtin Aggregation by Increasing Htt-N-Terminal Stability and Weakening Interactions with PolyQ Domain.

Smaoui MR, Mazza-Anthony C, Waldispühl J.

Comput Math Methods Med. 2016;2016:6247867. doi: 10.1155/2016/6247867. Epub 2016 Dec 14.

7.

Unraveling protein misfolding diseases using model systems.

Peffer S, Cope K, Morano KA.

Future Sci OA. 2015 Sep 1;1(2):FSO41. doi: 10.4155/fso.15.41. eCollection 2015 Sep. Review.

8.

Genetic architecture of natural variation in visual senescence in Drosophila.

Carbone MA, Yamamoto A, Huang W, Lyman RA, Meadors TB, Yamamoto R, Anholt RR, Mackay TF.

Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6620-E6629. Epub 2016 Oct 10.

9.

Real-time imaging of Huntingtin aggregates diverting target search and gene transcription.

Li L, Liu H, Dong P, Li D, Legant WR, Grimm JB, Lavis LD, Betzig E, Tjian R, Liu Z.

Elife. 2016 Aug 3;5. pii: e17056. doi: 10.7554/eLife.17056.

10.

A Drosophila model of Huntington disease-like 2 exhibits nuclear toxicity and distinct pathogenic mechanisms from Huntington disease.

Krench M, Cho RW, Littleton JT.

Hum Mol Genet. 2016 Aug 1;25(15):3164-3177. doi: 10.1093/hmg/ddw166. Epub 2016 Jun 10.

PMID:
27288455
11.

Aggregation of AcMNPV LEF-10 and Its Impact on Viral Late Gene Expression.

Xu X, Zhou X, Nan H, Zhao Y, Bai Y, Ou Y, Chen H.

PLoS One. 2016 May 6;11(5):e0154835. doi: 10.1371/journal.pone.0154835. eCollection 2016.

12.

Drosophila tools and assays for the study of human diseases.

Ugur B, Chen K, Bellen HJ.

Dis Model Mech. 2016 Mar;9(3):235-44. doi: 10.1242/dmm.023762. Review.

13.

Molecular Basis of Orb2 Amyloidogenesis and Blockade of Memory Consolidation.

Hervás R, Li L, Majumdar A, Fernández-Ramírez Mdel C, Unruh JR, Slaughter BD, Galera-Prat A, Santana E, Suzuki M, Nagai Y, Bruix M, Casas-Tintó S, Menéndez M, Laurents DV, Si K, Carrión-Vázquez M.

PLoS Biol. 2016 Jan 26;14(1):e1002361. doi: 10.1371/journal.pbio.1002361. eCollection 2016 Jan.

14.

Curcumin modulates cell death and is protective in Huntington's disease model.

Chongtham A, Agrawal N.

Sci Rep. 2016 Jan 5;6:18736. doi: 10.1038/srep18736.

15.

Cholesterol Modifies Huntingtin Binding to, Disruption of, and Aggregation on Lipid Membranes.

Gao X, Campbell WA 4th, Chaibva M, Jain P, Leslie AE, Frey SL, Legleiter J.

Biochemistry. 2016 Jan 12;55(1):92-102. doi: 10.1021/acs.biochem.5b00900. Epub 2015 Dec 22.

16.

Early-onset sleep defects in Drosophila models of Huntington's disease reflect alterations of PKA/CREB signaling.

Gonzales ED, Tanenhaus AK, Zhang J, Chaffee RP, Yin JC.

Hum Mol Genet. 2016 Mar 1;25(5):837-52. doi: 10.1093/hmg/ddv482. Epub 2015 Nov 24.

17.

Metazoan Hsp70-based protein disaggregases: emergence and mechanisms.

Nillegoda NB, Bukau B.

Front Mol Biosci. 2015 Oct 9;2:57. doi: 10.3389/fmolb.2015.00057. eCollection 2015. Review.

18.

Huntingtin differentially regulates the axonal transport of a sub-set of Rab-containing vesicles in vivo.

White JA 2nd, Anderson E, Zimmerman K, Zheng KH, Rouhani R, Gunawardena S.

Hum Mol Genet. 2015 Dec 20;24(25):7182-95. doi: 10.1093/hmg/ddv415. Epub 2015 Oct 8.

19.

Transcellular spreading of huntingtin aggregates in the Drosophila brain.

Babcock DT, Ganetzky B.

Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):E5427-33. doi: 10.1073/pnas.1516217112. Epub 2015 Sep 8.

20.

Studying polyglutamine diseases in Drosophila.

Xu Z, Tito AJ, Rui YN, Zhang S.

Exp Neurol. 2015 Dec;274(Pt A):25-41. doi: 10.1016/j.expneurol.2015.08.002. Epub 2015 Aug 6. Review.

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