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Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.

Morgenstern Y, Das Adhikari U, Ayyash M, Elyada E, Tóth B, Moor A, Itzkovitz S, Ben-Neriah Y.

EMBO J. 2017 Oct 16;36(20):3046-3061. doi: 10.15252/embj.201696253. Epub 2017 Sep 28.


Autophagy suppresses Ras-driven epithelial tumourigenesis by limiting the accumulation of reactive oxygen species.

Manent J, Banerjee S, de Matos Simoes R, Zoranovic T, Mitsiades C, Penninger JM, Simpson KJ, Humbert PO, Richardson HE.

Oncogene. 2017 Oct 5;36(40):5576-5592. doi: 10.1038/onc.2017.175. Epub 2017 Jun 5. Erratum in: Oncogene. 2017 Oct 5;36(40):5658-5660.


Mechanisms of polarity protein expression control.

Ahmed SM, Macara IG.

Curr Opin Cell Biol. 2016 Oct;42:38-45. doi: 10.1016/ Epub 2016 Apr 16. Review.


Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics.

Okerberg ES, Hainley A, Brown H, Aban A, Alemayehu S, Shih A, Wu J, Patricelli MP, Kozarich JW, Nomanbhoy T, Rosenblum JS.

PLoS One. 2016 Mar 31;11(3):e0152934. doi: 10.1371/journal.pone.0152934. eCollection 2016. Erratum in: PLoS One. 2017 Feb 15;12 (2):e0172649.


Loss of the cell polarity determinant human Discs-large is a novel molecular marker of nodal involvement and poor prognosis in endometrial cancer.

Sugihara T, Nakagawa S, Sasajima Y, Ichinose T, Hiraike H, Kondo F, Uozaki H, Fukusato T, Ayabe T.

Br J Cancer. 2016 Apr 26;114(9):1012-8. doi: 10.1038/bjc.2016.24. Epub 2016 Mar 22.


Regulation of hedgehog Ligand Expression by the N-End Rule Ubiquitin-Protein Ligase Hyperplastic Discs and the Drosophila GSK3β Homologue, Shaggy.

Moncrieff S, Moncan M, Scialpi F, Ditzel M.

PLoS One. 2015 Sep 3;10(9):e0136760. doi: 10.1371/journal.pone.0136760. eCollection 2015.


High casein kinase 1 epsilon levels are correlated with better prognosis in subsets of patients with breast cancer.

Lopez-Guerra JL, Verdugo-Sivianes EM, Otero-Albiol D, Vieites B, Ortiz-Gordillo MJ, De León JM, Praena-Fernandez JM, Marin JJ, Carnero A.

Oncotarget. 2015 Oct 6;6(30):30343-56. doi: 10.18632/oncotarget.4850.


The MLLE domain of the ubiquitin ligase UBR5 binds to its catalytic domain to regulate substrate binding.

Muñoz-Escobar J, Matta-Camacho E, Kozlov G, Gehring K.

J Biol Chem. 2015 Sep 11;290(37):22841-50. doi: 10.1074/jbc.M115.672246. Epub 2015 Jul 29.


Expression of polarity genes in human cancer.

Lin WH, Asmann YW, Anastasiadis PZ.

Cancer Inform. 2015 Mar 30;14(Suppl 3):15-28. doi: 10.4137/CIN.S18964. eCollection 2015.


EDD, a ubiquitin-protein ligase of the N-end rule pathway, associates with spindle assembly checkpoint components and regulates the mitotic response to nocodazole.

Scialpi F, Mellis D, Ditzel M.

J Biol Chem. 2015 May 15;290(20):12585-94. doi: 10.1074/jbc.M114.625673. Epub 2015 Apr 1.


Biological functions of casein kinase 1 isoforms and putative roles in tumorigenesis.

Schittek B, Sinnberg T.

Mol Cancer. 2014 Oct 11;13:231. doi: 10.1186/1476-4598-13-231. Review.


Screening for E3-ubiquitin ligase inhibitors: challenges and opportunities.

Landré V, Rotblat B, Melino S, Bernassola F, Melino G.

Oncotarget. 2014 Sep 30;5(18):7988-8013. Review.


DLG5 in cell polarity maintenance and cancer development.

Liu J, Li J, Ren Y, Liu P.

Int J Biol Sci. 2014 May 3;10(5):543-9. doi: 10.7150/ijbs.8888. eCollection 2014. Review.


The CK1 Family: Contribution to Cellular Stress Response and Its Role in Carcinogenesis.

Knippschild U, Krüger M, Richter J, Xu P, García-Reyes B, Peifer C, Halekotte J, Bakulev V, Bischof J.

Front Oncol. 2014 May 19;4:96. doi: 10.3389/fonc.2014.00096. eCollection 2014. Review.


Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland.

Godde NJ, Sheridan JM, Smith LK, Pearson HB, Britt KL, Galea RC, Yates LL, Visvader JE, Humbert PO.

PLoS Genet. 2014 May 22;10(5):e1004323. doi: 10.1371/journal.pgen.1004323. eCollection 2014 May.


Casein kinase 1 epsilon expression predicts poorer prognosis in low T-stage oral cancer patients.

Lin SH, Lin YM, Yeh CM, Chen CJ, Chen MW, Hung HF, Yeh KT, Yang SF.

Int J Mol Sci. 2014 Feb 19;15(2):2876-91. doi: 10.3390/ijms15022876.


EDD enhances cell survival and cisplatin resistance and is a therapeutic target for epithelial ovarian cancer.

Bradley A, Zheng H, Ziebarth A, Sakati W, Branham-O'Connor M, Blumer JB, Liu Y, Kistner-Griffin E, Rodriguez-Aguayo C, Lopez-Berestein G, Sood AK, Landen CN Jr, Eblen ST.

Carcinogenesis. 2014 May;35(5):1100-9. doi: 10.1093/carcin/bgt489. Epub 2013 Dec 30.


Metabotropic glutamate receptor 1 expression and its polymorphic variants associate with breast cancer phenotypes.

Mehta MS, Dolfi SC, Bronfenbrener R, Bilal E, Chen C, Moore D, Lin Y, Rahim H, Aisner S, Kersellius RD, Teh J, Chen S, Toppmeyer DL, Medina DJ, Ganesan S, Vazquez A, Hirshfield KM.

PLoS One. 2013 Jul 26;8(7):e69851. doi: 10.1371/journal.pone.0069851. Print 2013.


CK1δ kinase activity is modulated by Chk1-mediated phosphorylation.

Bischof J, Randoll SJ, Süßner N, Henne-Bruns D, Pinna LA, Knippschild U.

PLoS One. 2013 Jul 4;8(7):e68803. doi: 10.1371/journal.pone.0068803. Print 2013.

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