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Items: 1 to 20 of 46


Structural basis of kainate subtype glutamate receptor desensitization.

Meyerson JR, Chittori S, Merk A, Rao P, Han TH, Serpe M, Mayer ML, Subramaniam S.

Nature. 2016 Sep 22;537(7621):567-571. doi: 10.1038/nature19352. Epub 2016 Aug 31.


Structural rearrangement of the intracellular domains during AMPA receptor activation.

Zachariassen LG, Katchan L, Jensen AG, Pickering DS, Plested AJ, Kristensen AS.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):E3950-9. doi: 10.1073/pnas.1601747113. Epub 2016 Jun 16.


Distinct Structural Pathways Coordinate the Activation of AMPA Receptor-Auxiliary Subunit Complexes.

Dawe GB, Musgaard M, Aurousseau MR, Nayeem N, Green T, Biggin PC, Bowie D.

Neuron. 2016 Mar 16;89(6):1264-76. doi: 10.1016/j.neuron.2016.01.038. Epub 2016 Feb 25.


Retour aux sources: defining the structural basis of glutamate receptor activation.

Dawe GB, Aurousseau MR, Daniels BA, Bowie D.

J Physiol. 2015 Jan 1;593(1):97-110. doi: 10.1113/jphysiol.2014.277921. Epub 2014 Oct 21. Review.


AMPA receptor potentiators: from drug design to cognitive enhancement.

Partin KM.

Curr Opin Pharmacol. 2015 Feb;20:46-53. doi: 10.1016/j.coph.2014.11.002. Epub 2014 Nov 27. Review.


Molecular dissection of the interaction between the AMPA receptor and cornichon homolog-3.

Shanks NF, Cais O, Maruo T, Savas JN, Zaika EI, Azumaya CM, Yates JR 3rd, Greger I, Nakagawa T.

J Neurosci. 2014 Sep 3;34(36):12104-20. doi: 10.1523/JNEUROSCI.0595-14.2014.


Structural mechanism of glutamate receptor activation and desensitization.

Meyerson JR, Kumar J, Chittori S, Rao P, Pierson J, Bartesaghi A, Mayer ML, Subramaniam S.

Nature. 2014 Oct 16;514(7522):328-34. doi: 10.1038/nature13603. Epub 2014 Aug 3.


X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.

Chen L, Dürr KL, Gouaux E.

Science. 2014 Aug 29;345(6200):1021-6. doi: 10.1126/science.1258409. Epub 2014 Aug 7.


The N-terminal domain modulates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor desensitization.

Möykkynen T, Coleman SK, Semenov A, Keinänen K.

J Biol Chem. 2014 May 9;289(19):13197-205. doi: 10.1074/jbc.M113.526301. Epub 2014 Mar 20.


A conformational intermediate in glutamate receptor activation.

Lau AY, Salazar H, Blachowicz L, Ghisi V, Plested AJ, Roux B.

Neuron. 2013 Aug 7;79(3):492-503. doi: 10.1016/j.neuron.2013.06.003.


Modulation of homomeric and heteromeric kainate receptors by the auxiliary subunit Neto1.

Fisher JL, Mott DD.

J Physiol. 2013 Oct 1;591(19):4711-24. doi: 10.1113/jphysiol.2013.256776. Epub 2013 Jun 24.


Correlating efficacy and desensitization with GluK2 ligand-binding domain movements.

Nayeem N, Mayans O, Green T.

Open Biol. 2013 May 29;3(5):130051. doi: 10.1098/rsob.130051.


Glutamate receptor desensitization is mediated by changes in quaternary structure of the ligand binding domain.

Schauder DM, Kuybeda O, Zhang J, Klymko K, Bartesaghi A, Borgnia MJ, Mayer ML, Subramaniam S.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):5921-6. doi: 10.1073/pnas.1217549110. Epub 2013 Mar 25.


Zinc potentiates GluK3 glutamate receptor function by stabilizing the ligand binding domain dimer interface.

Veran J, Kumar J, Pinheiro PS, Athané A, Mayer ML, Perrais D, Mulle C.

Neuron. 2012 Nov 8;76(3):565-78. doi: 10.1016/j.neuron.2012.08.027.


Domain architecture of a calcium-permeable AMPA receptor in a ligand-free conformation.

Midgett CR, Gill A, Madden DR.

Front Mol Neurosci. 2012 Jan 2;4:56. doi: 10.3389/fnmol.2011.00056. eCollection 2012.


Emerging models of glutamate receptor ion channel structure and function.

Mayer ML.

Structure. 2011 Oct 12;19(10):1370-80. doi: 10.1016/j.str.2011.08.009. Review.


NMDA receptor activation requires remodelling of intersubunit contacts within ligand-binding heterodimers.

Borschel WF, Murthy SE, Kasperek EM, Popescu GK.

Nat Commun. 2011 Oct 11;2:498. doi: 10.1038/ncomms1512.


Interaction of the M4 segment with other transmembrane segments is required for surface expression of mammalian α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors.

Salussolia CL, Corrales A, Talukder I, Kazi R, Akgul G, Bowen M, Wollmuth LP.

J Biol Chem. 2011 Nov 18;286(46):40205-18. doi: 10.1074/jbc.M111.268839. Epub 2011 Sep 19.


Structure and assembly mechanism for heteromeric kainate receptors.

Kumar J, Schuck P, Mayer ML.

Neuron. 2011 Jul 28;71(2):319-31. doi: 10.1016/j.neuron.2011.05.038.


Not all desensitizations are created equal: physiological evidence that AMPA receptor desensitization differs for kainate and glutamate.

Levchenko-Lambert Y, Turetsky DM, Patneau DK.

J Neurosci. 2011 Jun 22;31(25):9359-67. doi: 10.1523/JNEUROSCI.6761-10.2011.

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