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In vitro models of cancer stem cells and clinical applications.

S Franco S, Szczesna K, Iliou MS, Al-Qahtani M, Mobasheri A, Kobolák J, Dinnyés A.

BMC Cancer. 2016 Sep 30;16(Suppl 2):738. Review.


A potent and selective small molecule inhibitor of sirtuin 1 promotes differentiation of pluripotent P19 cells into functional neurons.

Kim BS, Lee CH, Chang GE, Cheong E, Shin I.

Sci Rep. 2016 Sep 29;6:34324. doi: 10.1038/srep34324.


Novel β-carbolines against colorectal cancer cell growth via inhibition of Wnt/β-catenin signaling.

Li X, Bai B, Liu L, Ma P, Kong L, Yan J, Zhang J, Ye Z, Zhou H, Mao B, Zhu H, Li Y.

Cell Death Discov. 2015 Oct 5;1:15033. doi: 10.1038/cddiscovery.2015.33.


β-Catenin C-terminal signals suppress p53 and are essential for artery formation.

Riascos-Bernal DF, Chinnasamy P, Cao LL, Dunaway CM, Valenta T, Basler K, Sibinga NE.

Nat Commun. 2016 Aug 8;7:12389. doi: 10.1038/ncomms12389.


Wnt/Beta-Catenin Signal Inhibitor HC-1 Sensitizes Oral Squamous Cell Carcinoma Cells to 5-Fluorouracil through Reduction of CD44-Positive Population.

Yokogi S, Tsubota T, Kanki K, Azumi J, Itaba N, Oka H, Morimoto M, Ryoke K, Shiota G.

Yonago Acta Med. 2016 Jun 29;59(2):93-9.


Direct Targeting of β-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/β-Catenin Signaling.

Hwang SY, Deng X, Byun S, Lee C, Lee SJ, Suh H, Zhang J, Kang Q, Zhang T, Westover KD, Mandinova A, Lee SW.

Cell Rep. 2016 Jun 28;16(1):28-36. doi: 10.1016/j.celrep.2016.05.071.


Advances in targeted and immunobased therapies for colorectal cancer in the genomic era.

Seow HF, Yip WK, Fifis T.

Onco Targets Ther. 2016 Mar 31;9:1899-920. doi: 10.2147/OTT.S95101. Review.


SOX9 drives WNT pathway activation in prostate cancer.

Ma F, Ye H, He HH, Gerrin SJ, Chen S, Tanenbaum BA, Cai C, Sowalsky AG, He L, Wang H, Balk SP, Yuan X.

J Clin Invest. 2016 May 2;126(5):1745-58. doi: 10.1172/JCI78815.


Targeting Wnt/β-catenin pathway in hepatocellular carcinoma treatment.

Vilchez V, Turcios L, Marti F, Gedaly R.

World J Gastroenterol. 2016 Jan 14;22(2):823-32. doi: 10.3748/wjg.v22.i2.823. Review.


Adenomatous polyposis coli (APC) regulates miR17-92 cluster through β-catenin pathway in colorectal cancer.

Li Y, Lauriola M, Kim D, Francesconi M, D'Uva G, Shibata D, Malafa MP, Yeatman TJ, Coppola D, Solmi R, Cheng JQ.

Oncogene. 2016 Sep 1;35(35):4558-68. doi: 10.1038/onc.2015.522.


Modulation of Protein-Protein Interactions for the Development of Novel Therapeutics.

Petta I, Lievens S, Libert C, Tavernier J, De Bosscher K.

Mol Ther. 2016 Apr;24(4):707-18. doi: 10.1038/mt.2015.214. Review.


The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies.

Yang K, Wang X, Zhang H, Wang Z, Nan G, Li Y, Zhang F, Mohammed MK, Haydon RC, Luu HH, Bi Y, He TC.

Lab Invest. 2016 Feb;96(2):116-36. doi: 10.1038/labinvest.2015.144.


Human mesenchymal stem cell-engineered hepatic cell sheets accelerate liver regeneration in mice.

Itaba N, Matsumi Y, Okinaka K, Ashla AA, Kono Y, Osaki M, Morimoto M, Sugiyama N, Ohashi K, Okano T, Shiota G.

Sci Rep. 2015 Nov 10;5:16169. doi: 10.1038/srep16169.


Inhibition of the Tcf/beta-catenin complex increases apoptosis and impairs adrenocortical tumor cell proliferation and adrenal steroidogenesis.

Leal LF, Bueno AC, Gomes DC, Abduch R, de Castro M, Antonini SR.

Oncotarget. 2015 Dec 15;6(40):43016-32. doi: 10.18632/oncotarget.5513.


Development of anticancer agents targeting the Wnt/β-catenin signaling.

Zhang X, Hao J.

Am J Cancer Res. 2015 Jul 15;5(8):2344-60. Review.


Signaling in Fibrosis: TGF-β, WNT, and YAP/TAZ Converge.

Piersma B, Bank RA, Boersema M.

Front Med (Lausanne). 2015 Sep 3;2:59. doi: 10.3389/fmed.2015.00059. Review.


Anti-angiogenic and anti-proliferative effects of inhibition of HIF-1α by p-HIF-1α RNAi in colorectal cancer.

Qiu YY, Hu SJ, Bao YJ, Liang B, Yan CN, Shi XJ, Yu H, Zou Y, Tang LR, Tang QF, Feng W, Yin PH.

Int J Clin Exp Pathol. 2015 Jul 1;8(7):7913-20.


Targeting the WNT Signaling Pathway in Cancer Therapeutics.

Tai D, Wells K, Arcaroli J, Vanderbilt C, Aisner DL, Messersmith WA, Lieu CH.

Oncologist. 2015 Oct;20(10):1189-98. doi: 10.1634/theoncologist.2015-0057. Review.


Targeting Wnt signaling in colorectal cancer. A Review in the Theme: Cell Signaling: Proteins, Pathways and Mechanisms.

Novellasdemunt L, Antas P, Li VS.

Am J Physiol Cell Physiol. 2015 Oct 15;309(8):C511-21. doi: 10.1152/ajpcell.00117.2015. Review.

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