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Items: 1 to 20 of 210

1.

Insight into the Selectivity of the G7-18NATE Inhibitor Peptide for the Grb7-SH2 Domain Target.

Watson GM, Lucas WAH, Gunzburg MJ, Wilce JA.

Front Mol Biosci. 2017 Sep 26;4:64. doi: 10.3389/fmolb.2017.00064. eCollection 2017.

2.

Nuclear Gene 33/Mig6 regulates the DNA damage response through an ATM serine/threonine kinase-dependent mechanism.

Li C, Park S, Zhang X, Eisenberg LM, Zhao H, Darzynkiewicz Z, Xu D.

J Biol Chem. 2017 Oct 6;292(40):16746-16759. doi: 10.1074/jbc.M117.803338. Epub 2017 Aug 25.

PMID:
28842482
3.

Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain.

Hanamura K, Washburn HR, Sheffler-Collins SI, Xia NL, Henderson N, Tillu DV, Hassler S, Spellman DS, Zhang G, Neubert TA, Price TJ, Dalva MB.

PLoS Biol. 2017 Jul 18;15(7):e2002457. doi: 10.1371/journal.pbio.2002457. eCollection 2017 Jul.

4.

Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria.

Luo X, Fu G, Wang RE, Zhu X, Zambaldo C, Liu R, Liu T, Lyu X, Du J, Xuan W, Yao A, Reed SA, Kang M, Zhang Y, Guo H, Huang C, Yang PY, Wilson IA, Schultz PG, Wang F.

Nat Chem Biol. 2017 Aug;13(8):845-849. doi: 10.1038/nchembio.2405. Epub 2017 Jun 12.

5.

Cylindromatosis Tumor Suppressor Protein (CYLD) Deubiquitinase is Necessary for Proper Ubiquitination and Degradation of the Epidermal Growth Factor Receptor.

Sanchez-Quiles V, Akimov V, Osinalde N, Francavilla C, Puglia M, Barrio-Hernandez I, Kratchmarova I, Olsen JV, Blagoev B.

Mol Cell Proteomics. 2017 Aug;16(8):1433-1446. doi: 10.1074/mcp.M116.066423. Epub 2017 Jun 1.

PMID:
28572092
6.

Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways.

Wee P, Wang Z.

Cancers (Basel). 2017 May 17;9(5). pii: E52. doi: 10.3390/cancers9050052. Review.

7.

Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies.

Kükenshöner T, Schmit NE, Bouda E, Sha F, Pojer F, Koide A, Seeliger M, Koide S, Hantschel O.

J Mol Biol. 2017 May 5;429(9):1364-1380. doi: 10.1016/j.jmb.2017.03.023. Epub 2017 Mar 25.

8.

Advances in mass spectrometry based strategies to study receptor tyrosine kinases.

Vyse S, Desmond H, Huang PH.

IUCrJ. 2017 Feb 23;4(Pt 2):119-130. doi: 10.1107/S2052252516020546. eCollection 2017 Mar 1. Review.

9.

High-Content Imaging Platform for Profiling Intracellular Signaling Network Activity in Living Cells.

Kuchenov D, Laketa V, Stein F, Salopiata F, Klingmüller U, Schultz C.

Cell Chem Biol. 2016 Dec 22;23(12):1550-1559. doi: 10.1016/j.chembiol.2016.11.008. Epub 2016 Dec 8.

10.

An atlas of human kinase regulation.

Ochoa D, Jonikas M, Lawrence RT, El Debs B, Selkrig J, Typas A, Villén J, Santos SD, Beltrao P.

Mol Syst Biol. 2016 Dec 1;12(12):888. doi: 10.15252/msb.20167295.

11.

Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer.

Drake JM, Paull EO, Graham NA, Lee JK, Smith BA, Titz B, Stoyanova T, Faltermeier CM, Uzunangelov V, Carlin DE, Fleming DT, Wong CK, Newton Y, Sudha S, Vashisht AA, Huang J, Wohlschlegel JA, Graeber TG, Witte ON, Stuart JM.

Cell. 2016 Aug 11;166(4):1041-1054. doi: 10.1016/j.cell.2016.07.007. Epub 2016 Aug 4.

12.

Multiplex matrix network analysis of protein complexes in the human TCR signalosome.

Smith SE, Neier SC, Reed BK, Davis TR, Sinnwell JP, Eckel-Passow JE, Sciallis GF, Wieland CN, Torgerson RR, Gil D, Neuhauser C, Schrum AG.

Sci Signal. 2016 Aug 2;9(439):rs7. doi: 10.1126/scisignal.aad7279.

13.

PredPhos: an ensemble framework for structure-based prediction of phosphorylation sites.

Gao Y, Hao W, Gu J, Liu D, Fan C, Chen Z, Deng L.

J Biol Res (Thessalon). 2016 Jul 4;23(Suppl 1):12. doi: 10.1186/s40709-016-0042-y. eCollection 2016 May.

14.

Lipids Regulate Lck Protein Activity through Their Interactions with the Lck Src Homology 2 Domain.

Sheng R, Jung DJ, Silkov A, Kim H, Singaram I, Wang ZG, Xin Y, Kim E, Park MJ, Thiagarajan-Rosenkranz P, Smrt S, Honig B, Baek K, Ryu S, Lorieau J, Kim YM, Cho W.

J Biol Chem. 2016 Aug 19;291(34):17639-50. doi: 10.1074/jbc.M116.720284. Epub 2016 Jun 22.

15.

Time-resolved multimodal analysis of Src Homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases.

Jadwin JA, Oh D, Curran TG, Ogiue-Ikeda M, Jia L, White FM, Machida K, Yu J, Mayer BJ.

Elife. 2016 Apr 12;5:e11835. doi: 10.7554/eLife.11835.

16.

SH2 Domains Serve as Lipid-Binding Modules for pTyr-Signaling Proteins.

Park MJ, Sheng R, Silkov A, Jung DJ, Wang ZG, Xin Y, Kim H, Thiagarajan-Rosenkranz P, Song S, Yoon Y, Nam W, Kim I, Kim E, Lee DG, Chen Y, Singaram I, Wang L, Jang MH, Hwang CS, Honig B, Ryu S, Lorieau J, Kim YM, Cho W.

Mol Cell. 2016 Apr 7;62(1):7-20. doi: 10.1016/j.molcel.2016.01.027. Epub 2016 Mar 24.

17.

A Thousand and One Receptor Tyrosine Kinases: Wherein the Specificity?

Vasudevan HN, Soriano P.

Curr Top Dev Biol. 2016;117:393-404. doi: 10.1016/bs.ctdb.2015.10.016. Epub 2016 Jan 7. Review.

18.

Different Epidermal Growth Factor Receptor (EGFR) Agonists Produce Unique Signatures for the Recruitment of Downstream Signaling Proteins.

Ronan T, Macdonald-Obermann JL, Huelsmann L, Bessman NJ, Naegle KM, Pike LJ.

J Biol Chem. 2016 Mar 11;291(11):5528-40. doi: 10.1074/jbc.M115.710087. Epub 2016 Jan 19.

19.

Feedback regulation of G protein-coupled receptor signaling by GRKs and arrestins.

Black JB, Premont RT, Daaka Y.

Semin Cell Dev Biol. 2016 Feb;50:95-104. doi: 10.1016/j.semcdb.2015.12.015. Epub 2016 Jan 7. Review.

20.

Toxicological Assessment of CoO and La2O3 Metal Oxide Nanoparticles in Human Small Airway Epithelial Cells.

Sisler JD, Pirela SV, Shaffer J, Mihalchik AL, Chisholm WP, Andrew ME, Schwegler-Berry D, Castranova V, Demokritou P, Qian Y.

Toxicol Sci. 2016 Apr;150(2):418-28. doi: 10.1093/toxsci/kfw005. Epub 2016 Jan 14.

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