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Items: 1 to 20 of 85


Molecular Simulations Suggest a Force-Dependent Mechanism of Vinculin Activation.

Sun L, Noel JK, Levine H, Onuchic JN.

Biophys J. 2017 Oct 17;113(8):1697-1710. doi: 10.1016/j.bpj.2017.08.037.


Biophysical Tools to Study Cellular Mechanotransduction.

Muhamed I, Chowdhury F, Maruthamuthu V.

Bioengineering (Basel). 2017 Feb 7;4(1). pii: E12. doi: 10.3390/bioengineering4010012. Review.


Cell-cell adhesion in metazoans relies on evolutionarily conserved features of the α-catenin·β-catenin-binding interface.

Shao X, Kang H, Loveless T, Lee GR, Seok C, Weis WI, Choi HJ, Hardin J.

J Biol Chem. 2017 Oct 6;292(40):16477-16490. doi: 10.1074/jbc.M117.795567. Epub 2017 Aug 25.


Single and collective cell migration: the mechanics of adhesions.

De Pascalis C, Etienne-Manneville S.

Mol Biol Cell. 2017 Jul 7;28(14):1833-1846. doi: 10.1091/mbc.E17-03-0134.


Genistein inhibits the growth and regulates the migration and invasion abilities of melanoma cells via the FAK/paxillin and MAPK pathways.

Cui S, Wang J, Wu Q, Qian J, Yang C, Bo P.

Oncotarget. 2017 Mar 28;8(13):21674-21691. doi: 10.18632/oncotarget.15535.


Vinculin in cell-cell and cell-matrix adhesions.

Bays JL, DeMali KA.

Cell Mol Life Sci. 2017 Aug;74(16):2999-3009. doi: 10.1007/s00018-017-2511-3. Epub 2017 Apr 11. Review.


Vinculin association with actin cytoskeleton is necessary for stiffness-dependent regulation of vinculin behavior.

Omachi T, Ichikawa T, Kimura Y, Ueda K, Kioka N.

PLoS One. 2017 Apr 7;12(4):e0175324. doi: 10.1371/journal.pone.0175324. eCollection 2017.


A Structural Model for Vinculin Insertion into PIP2-Containing Membranes and the Effect of Insertion on Vinculin Activation and Localization.

Thompson PM, Ramachandran S, Case LB, Tolbert CE, Tandon A, Pershad M, Dokholyan NV, Waterman CM, Campbell SL.

Structure. 2017 Feb 7;25(2):264-275. doi: 10.1016/j.str.2016.12.002. Epub 2017 Jan 12.


Drosophila vinculin is more harmful when hyperactive than absent, and can circumvent integrin to form adhesion complexes.

Maartens AP, Wellmann J, Wictome E, Klapholz B, Green H, Brown NH.

J Cell Sci. 2016 Dec 1;129(23):4354-4365. Epub 2016 Oct 13.


Molecular mechanisms of mechanotransduction in integrin-mediated cell-matrix adhesion.

Li Z, Lee H, Zhu C.

Exp Cell Res. 2016 Nov 15;349(1):85-94. doi: 10.1016/j.yexcr.2016.10.001. Epub 2016 Oct 6. Review.


Sustained α-catenin Activation at E-cadherin Junctions in the Absence of Mechanical Force.

Biswas KH, Hartman KL, Zaidel-Bar R, Groves JT.

Biophys J. 2016 Sep 6;111(5):1044-52. doi: 10.1016/j.bpj.2016.06.027.


Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.

Chinthalapudi K, Rangarajan ES, Brown DT, Izard T.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9539-44. doi: 10.1073/pnas.1600702113. Epub 2016 Aug 8.


Mechanisms and Functions of Vinculin Interactions with Phospholipids at Cell Adhesion Sites.

Izard T, Brown DT.

J Biol Chem. 2016 Feb 5;291(6):2548-55. doi: 10.1074/jbc.R115.686493. Epub 2016 Jan 4. Review.


Mechanosensitive components of integrin adhesions: Role of vinculin.

Atherton P, Stutchbury B, Jethwa D, Ballestrem C.

Exp Cell Res. 2016 Apr 10;343(1):21-27. doi: 10.1016/j.yexcr.2015.11.017. Epub 2015 Nov 24. Review.


Vinculin phosphorylation at residues Y100 and Y1065 is required for cellular force transmission.

Auernheimer V, Lautscham LA, Leidenberger M, Friedrich O, Kappes B, Fabry B, Goldmann WH.

J Cell Sci. 2015 Sep 15;128(18):3435-43. doi: 10.1242/jcs.172031. Epub 2015 Aug 3.


Talin Dependent Mechanosensitivity of Cell Focal Adhesions.

Yan J, Yao M, Goult BT, Sheetz MP.

Cell Mol Bioeng. 2015;8(1):151-159. Epub 2014 Nov 4. Review.


Lipid binding promotes oligomerization and focal adhesion activity of vinculin.

Chinthalapudi K, Rangarajan ES, Patil DN, George EM, Brown DT, Izard T.

J Cell Biol. 2014 Dec 8;207(5):643-56. doi: 10.1083/jcb.201404128.


Mechano-transduction: from molecules to tissues.

Pruitt BL, Dunn AR, Weis WI, Nelson WJ.

PLoS Biol. 2014 Nov 18;12(11):e1001996. doi: 10.1371/journal.pbio.1001996. eCollection 2014 Nov.


Expression patterns of microRNAs in porcine endometrium and their potential roles in embryo implantation and placentation.

Su L, Liu R, Cheng W, Zhu M, Li X, Zhao S, Yu M.

PLoS One. 2014 Feb 5;9(2):e87867. doi: 10.1371/journal.pone.0087867. eCollection 2014.


Vinculin and Rab5 complex is required [correction of requited]for uptake of Staphylococcus aureus and interleukin-6 expression.

Hagiwara M, Kokubu E, Sugiura S, Komatsu T, Tada H, Isoda R, Tanigawa N, Kato Y, Ishida N, Kobayashi K, Nakashima M, Ishihara K, Matsushita K.

PLoS One. 2014 Jan 23;9(1):e87373. doi: 10.1371/journal.pone.0087373. eCollection 2014.

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