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Liraglutide attenuates the osteoblastic differentiation of MC3T3‑E1 cells by modulating AMPK/mTOR signaling.

Hu XK, Yin XH, Zhang HQ, Guo CF, Tang MX.

Mol Med Rep. 2016 Oct;14(4):3662-8. doi: 10.3892/mmr.2016.5729. Epub 2016 Sep 6.


A Qualitative Model of the Differentiation Network in Chondrocyte Maturation: A Holistic View of Chondrocyte Hypertrophy.

Kerkhofs J, Leijten J, Bolander J, Luyten FP, Post JN, Geris L.

PLoS One. 2016 Aug 31;11(8):e0162052. doi: 10.1371/journal.pone.0162052. eCollection 2016.


Ligustrazine Inhibits Cartilage Endplate Hypertrophy via Suppression of TGF-β1.

Liu S, Zhao B, Shi H, Liang Q, Fu Y, Yang Z, Xu L, Wang Y, Bian Q.

Evid Based Complement Alternat Med. 2016;2016:1042489. doi: 10.1155/2016/1042489. Epub 2016 Aug 2.


Mechanobiology of TGFβ signaling in the skeleton.

Rys JP, Monteiro DA, Alliston T.

Matrix Biol. 2016 May-Jul;52-54:413-425. doi: 10.1016/j.matbio.2016.02.002. Epub 2016 Feb 12. Review.


Systemic neutralization of TGF-β attenuates osteoarthritis.

Xie L, Tintani F, Wang X, Li F, Zhen G, Qiu T, Wan M, Crane J, Chen Q, Cao X.

Ann N Y Acad Sci. 2016 Jul;1376(1):53-64. doi: 10.1111/nyas.13000. Epub 2016 Feb 2.


Suppressive Effects of Insulin on Tumor Necrosis Factor-Dependent Early Osteoarthritic Changes Associated With Obesity and Type 2 Diabetes Mellitus.

Hamada D, Maynard R, Schott E, Drinkwater CJ, Ketz JP, Kates SL, Jonason JH, Hilton MJ, Zuscik MJ, Mooney RA.

Arthritis Rheumatol. 2016 Jun;68(6):1392-402. doi: 10.1002/art.39561.


Gene Therapy for Cartilage Repair.

Madry H, Orth P, Cucchiarini M.

Cartilage. 2011 Jul;2(3):201-25. doi: 10.1177/1947603510392914. Review.


TGF-β signaling and the development of osteoarthritis.

Shen J, Li S, Chen D.

Bone Res. 2014;2. pii: 14002.


Interplay between cartilage and subchondral bone contributing to pathogenesis of osteoarthritis.

Sharma AR, Jagga S, Lee SS, Nam JS.

Int J Mol Sci. 2013 Sep 30;14(10):19805-30. doi: 10.3390/ijms141019805. Review.


rAAV-mediated overexpression of TGF-β stably restructures human osteoarthritic articular cartilage in situ.

Venkatesan JK, Rey-Rico A, Schmitt G, Wezel A, Madry H, Cucchiarini M.

J Transl Med. 2013 Sep 13;11:211. doi: 10.1186/1479-5876-11-211.


Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis.

Zhen G, Wen C, Jia X, Li Y, Crane JL, Mears SC, Askin FB, Frassica FJ, Chang W, Yao J, Carrino JA, Cosgarea A, Artemov D, Chen Q, Zhao Z, Zhou X, Riley L, Sponseller P, Wan M, Lu WW, Cao X.

Nat Med. 2013 Jun;19(6):704-12. doi: 10.1038/nm.3143. Epub 2013 May 19.


Osteoimmunology and the influence of pro-inflammatory cytokines on osteoclasts.

Zupan J, Jeras M, Marc J.

Biochem Med (Zagreb). 2013;23(1):43-63. Review.


New findings in osteoarthritis pathogenesis: therapeutic implications.

Pulsatelli L, Addimanda O, Brusi V, Pavloska B, Meliconi R.

Ther Adv Chronic Dis. 2013 Jan;4(1):23-43. doi: 10.1177/2040622312462734.


Alterations in periarticular bone and cross talk between subchondral bone and articular cartilage in osteoarthritis.

Goldring SR.

Ther Adv Musculoskelet Dis. 2012 Aug;4(4):249-58. doi: 10.1177/1759720X12437353.


Prevalence of magnetic resonance imaging-defined atrophic and hypertrophic phenotypes of knee osteoarthritis in a population-based cohort.

Roemer FW, Guermazi A, Niu J, Zhang Y, Mohr A, Felson DT.

Arthritis Rheum. 2012 Feb;64(2):429-37. doi: 10.1002/art.33344.


Developmental mechanisms in articular cartilage degradation in osteoarthritis.

Tchetina EV.

Arthritis. 2011;2011:683970. doi: 10.1155/2011/683970. Epub 2010 Dec 29.


High density micromass cultures of a human chondrocyte cell line: a reliable assay system to reveal the modulatory functions of pharmacological agents.

Greco KV, Iqbal AJ, Rattazzi L, Nalesso G, Moradi-Bidhendi N, Moore AR, Goldring MB, Dell'Accio F, Perretti M.

Biochem Pharmacol. 2011 Dec 15;82(12):1919-29. doi: 10.1016/j.bcp.2011.09.009. Epub 2011 Sep 16.


Age-dependent alteration of TGF-β signalling in osteoarthritis.

van der Kraan PM, Goumans MJ, Blaney Davidson E, ten Dijke P.

Cell Tissue Res. 2012 Jan;347(1):257-65. doi: 10.1007/s00441-011-1194-6. Epub 2011 Jun 4. Review.


Association between expression of the bone morphogenetic proteins 2 and 7 in the repair of circumscribed cartilage lesions with clinical outcome.

Schmal H, Niemeyer P, Zwingmann J, Stoffel F, Südkamp NP, Mehlhorn AT.

BMC Musculoskelet Disord. 2010 Jul 29;11:170. doi: 10.1186/1471-2474-11-170.

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