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Homozygous p.Ser267Phe in SLC10A1 is associated with a new type of hypercholanemia and implications for personalized medicine.

Liu R, Chen C, Xia X, Liao Q, Wang Q, Newcombe PJ, Xu S, Chen M, Ding Y, Li X, Liao Z, Li F, Du M, Huang H, Dong R, Deng W, Wang Y, Zeng B, Pan Q, Jiang D, Zeng H, Sham P, Cao Y, Maxwell PH, Gao ZL, Peng L, Wang Y.

Sci Rep. 2017 Aug 23;7(1):9214. doi: 10.1038/s41598-017-07012-2.


Comprehensive assessment showed no associations of variants at the SLC10A1 locus with susceptibility to persistent HBV infection among Southern Chinese.

Zhang Y, Li Y, Wu M, Cao P, Liu X, Ren Q, Zhai Y, Xie B, Hu Y, Hu Z, Bei J, Ping J, Liu X, Yu Y, Guo B, Lu H, Liu G, Zhang H, Cui Y, Mo Z, Shen H, Zeng YX, He F, Zhang H, Zhou G.

Sci Rep. 2017 Apr 21;7:46490. doi: 10.1038/srep46490.


Bile Acid Uptake Transporters as Targets for Therapy.

Slijepcevic D, van de Graaf SF.

Dig Dis. 2017;35(3):251-258. doi: 10.1159/000450983. Epub 2017 Mar 1. Review.


Lack of Ser267Phe variant of sodium taurocholate cotransporting polypeptide among Moroccans regardless of hepatitis B virus infection status.

Ezzikouri S, Chihab H, Elhabazi A, Wakrim L, Benjelloun S.

BMC Infect Dis. 2017 Jan 26;17(1):99. doi: 10.1186/s12879-017-2214-2.


Na+-taurocholate cotransporting polypeptide (NTCP/SLC10A1) ortholog in the marine skate Leucoraja erinacea is not a physiological bile salt transporter.

Yu D, Zhang H, Lionarons DA, Boyer JL, Cai SY.

Am J Physiol Regul Integr Comp Physiol. 2017 Apr 1;312(4):R477-R484. doi: 10.1152/ajpregu.00302.2016. Epub 2017 Jan 11.


Clinical and molecular study of a pediatric patient with sodium taurocholate cotransporting polypeptide deficiency.

Deng M, Mao M, Guo L, Chen FP, Wen WR, Song YZ.

Exp Ther Med. 2016 Nov;12(5):3294-3300. Epub 2016 Sep 27.


Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.

Lee HH, Leake BF, Kim RB, Ho RH.

Mol Pharmacol. 2017 Jan;91(1):14-24. Epub 2016 Oct 24.


A genetic variant of the NTCP gene is associated with HBV infection status in a Chinese population.

Yang J, Yang Y, Xia M, Wang L, Zhou W, Yang Y, Jiang Y, Wang H, Qian J, Jin L, Wang X.

BMC Cancer. 2016 Mar 12;16:211. doi: 10.1186/s12885-016-2257-6.


Polymorphisms of SLC22A9 (hOAT7) in Korean Females with Osteoporosis.

Ahn SK, Suh CK, Cha SH.

Korean J Physiol Pharmacol. 2015 Jul;19(4):319-25. doi: 10.4196/kjpp.2015.19.4.319. Epub 2015 Jun 30.


Contribution of hepatic organic anion-transporting polypeptides to docetaxel uptake and clearance.

Lee HH, Leake BF, Teft W, Tirona RG, Kim RB, Ho RH.

Mol Cancer Ther. 2015 Apr;14(4):994-1003. doi: 10.1158/1535-7163.MCT-14-0547. Epub 2015 Feb 18.


Dysregulation of retinoic acid receptor diminishes hepatocyte permissiveness to hepatitis B virus infection through modulation of sodium taurocholate cotransporting polypeptide (NTCP) expression.

Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Okada M, Sugiyama M, Kojima S, Tanaka Y, Mizokami M, Li J, Tong S, Wakita T.

J Biol Chem. 2015 Feb 27;290(9):5673-84. doi: 10.1074/jbc.M114.602540. Epub 2014 Dec 30.


Organic anion uptake by hepatocytes.

Wolkoff AW.

Compr Physiol. 2014 Oct;4(4):1715-35. doi: 10.1002/cphy.c140023. Review.


Not all (bile acids) who wander are lost: the first report of a patient with an isolated NTCP defect.

Karpen SJ, Dawson PA.

Hepatology. 2015 Jan;61(1):24-7. doi: 10.1002/hep.27294. Epub 2014 Nov 20. No abstract available.


Association of genetic variation of sodium taurocholate cotransporting polypeptide with chronic hepatitis B virus infection.

Li N, Zhang P, Yang C, Zhu Q, Li Z, Li F, Han Q, Wang Y, Lv Y, Wei P, Liu Z.

Genet Test Mol Biomarkers. 2014 Jun;18(6):425-9. doi: 10.1089/gtmb.2013.0491. Epub 2014 Apr 15.


Cysteine scanning mutagenesis of transmembrane domain 10 in organic anion transporting polypeptide 1B1.

Ohnishi S, Hays A, Hagenbuch B.

Biochemistry. 2014 Apr 15;53(14):2261-70. doi: 10.1021/bi500176e. Epub 2014 Apr 4.


NTCP and beyond: opening the door to unveil hepatitis B virus entry.

Watashi K, Urban S, Li W, Wakita T.

Int J Mol Sci. 2014 Feb 19;15(2):2892-905. doi: 10.3390/ijms15022892. Review.


Viral entry of hepatitis B and D viruses and bile salts transportation share common molecular determinants on sodium taurocholate cotransporting polypeptide.

Yan H, Peng B, Liu Y, Xu G, He W, Ren B, Jing Z, Sui J, Li W.

J Virol. 2014 Mar;88(6):3273-84. doi: 10.1128/JVI.03478-13. Epub 2014 Jan 3.


Clinical application of transcriptional activators of bile salt transporters.

Baghdasaryan A, Chiba P, Trauner M.

Mol Aspects Med. 2014 Jun;37:57-76. doi: 10.1016/j.mam.2013.12.001. Epub 2013 Dec 12. Review.


Sodium-dependent bile salt transporters of the SLC10A transporter family: more than solute transporters.

Anwer MS, Stieger B.

Pflugers Arch. 2014 Jan;466(1):77-89. doi: 10.1007/s00424-013-1367-0. Epub 2013 Oct 3. Review.


Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites.

Swift B, Nebot N, Lee JK, Han T, Proctor WR, Thakker DR, Lang D, Radtke M, Gnoth MJ, Brouwer KL.

Drug Metab Dispos. 2013 Jun;41(6):1179-86. doi: 10.1124/dmd.112.048181. Epub 2013 Mar 12.

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