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Items: 1 to 20 of 185


YAP/TAZ-CDC42 signaling regulates vascular tip cell migration.

Sakabe M, Fan J, Odaka Y, Liu N, Hassan A, Duan X, Stump P, Byerly L, Donaldson M, Hao J, Fruttiger M, Lu QR, Zheng Y, Lang RA, Xin M.

Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):10918-10923. doi: 10.1073/pnas.1704030114. Epub 2017 Sep 25.


NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology.

Kaimori JY, Lin CC, Outeda P, Garcia-Gonzalez MA, Menezes LF, Hartung EA, Li A, Wu G, Fujita H, Sato Y, Nakanuma Y, Yamamoto S, Ichimaru N, Takahara S, Isaka Y, Watnick T, Onuchic LF, Guay-Woodford LM, Germino GG.

Sci Rep. 2017 Aug 10;7(1):7733. doi: 10.1038/s41598-017-08284-4.


Heterogeneous Family of Cyclomodulins: Smart Weapons That Allow Bacteria to Hijack the Eukaryotic Cell Cycle and Promote Infections.

El-Aouar Filho RA, Nicolas A, De Paula Castro TL, Deplanche M, De Carvalho Azevedo VA, Goossens PL, Taieb F, Lina G, Le Loir Y, Berkova N.

Front Cell Infect Microbiol. 2017 May 23;7:208. doi: 10.3389/fcimb.2017.00208. eCollection 2017. Review. Erratum in: Front Cell Infect Microbiol. 2017 Aug 14;7:364.


Smurf1 inhibits integrin activation by controlling Kindlin-2 ubiquitination and degradation.

Wei X, Wang X, Zhan J, Chen Y, Fang W, Zhang L, Zhang H.

J Cell Biol. 2017 May 1;216(5):1455-1471. doi: 10.1083/jcb.201609073. Epub 2017 Apr 13.


Development and dynamics of cell polarity at a glance.

Campanale JP, Sun TY, Montell DJ.

J Cell Sci. 2017 Apr 1;130(7):1201-1207. doi: 10.1242/jcs.188599. Review.


A mammalian nervous-system-specific plasma membrane proteasome complex that modulates neuronal function.

Ramachandran KV, Margolis SS.

Nat Struct Mol Biol. 2017 Apr;24(4):419-430. doi: 10.1038/nsmb.3389. Epub 2017 Mar 13.


Contact guidance requires spatial control of leading-edge protrusion.

Ramirez-San Juan GR, Oakes PW, Gardel ML.

Mol Biol Cell. 2017 Apr 15;28(8):1043-1053. doi: 10.1091/mbc.E16-11-0769. Epub 2017 Feb 22.


SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts.

Xu Z, Greenblatt MB, Yan G, Feng H, Sun J, Lotinun S, Brady N, Baron R, Glimcher LH, Zou W.

Nat Commun. 2017 Feb 20;8:14570. doi: 10.1038/ncomms14570.


A dual role for the RhoGEF Ephexin5 in regulation of dendritic spine outgrowth.

Hamilton AM, Lambert JT, Parajuli LK, Vivas O, Park DK, Stein IS, Jahncke JN, Greenberg ME, Margolis SS, Zito K.

Mol Cell Neurosci. 2017 Apr;80:66-74. doi: 10.1016/j.mcn.2017.02.001. Epub 2017 Feb 7.


The Nedd8 Non-covalent Binding Region in the Smurf HECT Domain is Critical to its Ubiquitn Ligase Function.

He S, Cao Y, Xie P, Dong G, Zhang L.

Sci Rep. 2017 Feb 7;7:41364. doi: 10.1038/srep41364.


The Ubiquitin Ligase Smurf1 Functions in Selective Autophagy of Mycobacterium tuberculosis and Anti-tuberculous Host Defense.

Franco LH, Nair VR, Scharn CR, Xavier RJ, Torrealba JR, Shiloh MU, Levine B.

Cell Host Microbe. 2017 Jan 11;21(1):59-72. doi: 10.1016/j.chom.2016.11.002. Epub 2016 Dec 22. Erratum in: Cell Host Microbe. 2017 Sep 13;22(3):421-423.


RhoA Proteolysis Regulates the Actin Cytoskeleton in Response to Oxidative Stress.

Girouard MP, Pool M, Alchini R, Rambaldi I, Fournier AE.

PLoS One. 2016 Dec 19;11(12):e0168641. doi: 10.1371/journal.pone.0168641. eCollection 2016.


Monoubiquitination Inhibits the Actin Bundling Activity of Fascin.

Lin S, Lu S, Mulaj M, Fang B, Keeley T, Wan L, Hao J, Muschol M, Sun J, Yang S.

J Biol Chem. 2016 Dec 30;291(53):27323-27333. doi: 10.1074/jbc.M116.767640. Epub 2016 Nov 22.


Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-β.

Tripathi V, Sixt KM, Gao S, Xu X, Huang J, Weigert R, Zhou M, Zhang YE.

Mol Cell. 2016 Nov 3;64(3):549-564. doi: 10.1016/j.molcel.2016.09.013. Epub 2016 Oct 13.


Rho GTPases: Regulation and roles in cancer cell biology.

Haga RB, Ridley AJ.

Small GTPases. 2016 Oct;7(4):207-221. Epub 2016 Sep 14. Review.


A lateral signalling pathway coordinates shape volatility during cell migration.

Zhang L, Luga V, Armitage SK, Musiol M, Won A, Yip CM, Plotnikov SV, Wrana JL.

Nat Commun. 2016 May 26;7:11714. doi: 10.1038/ncomms11714.


H19 long noncoding RNA alters trophoblast cell migration and invasion by regulating TβR3 in placentae with fetal growth restriction.

Zuckerwise L, Li J, Lu L, Men Y, Geng T, Buhimschi CS, Buhimschi IA, Bukowski R, Guller S, Paidas M, Huang Y.

Oncotarget. 2016 Jun 21;7(25):38398-38407. doi: 10.18632/oncotarget.9534.


STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis.

Guen VJ, Gamble C, Perez DE, Bourassa S, Zappel H, Gärtner J, Lees JA, Colas P.

Cell Cycle. 2016;15(5):678-88. doi: 10.1080/15384101.2016.1147632.


The polarity protein Par3 regulates APP trafficking and processing through the endocytic adaptor protein Numb.

Sun M, Asghar SZ, Zhang H.

Neurobiol Dis. 2016 Sep;93:1-11. doi: 10.1016/j.nbd.2016.03.022. Epub 2016 Apr 9.

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