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Ectopic expression of Cripto-1 in transgenic mouse embryos causes hemorrhages, fatal cardiac defects and embryonic lethality.

Lin X, Zhao W, Jia J, Lin T, Xiao G, Wang S, Lin X, Liu Y, Chen L, Qin Y, Li J, Zhang T, Hao W, Chen B, Xie R, Cheng Y, Xu K, Yao K, Huang W, Xiao D, Sun Y.

Sci Rep. 2016 Sep 30;6:34501. doi: 10.1038/srep34501.


Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency.

Fiorenzano A, Pascale E, D'Aniello C, Acampora D, Bassalert C, Russo F, Andolfi G, Biffoni M, Francescangeli F, Zeuner A, Angelini C, Chazaud C, Patriarca EJ, Fico A, Minchiotti G.

Nat Commun. 2016 Sep 2;7:12589. doi: 10.1038/ncomms12589.


Genome-Wide Transcriptome and Binding Sites Analyses Identify Early FOX Expressions for Enhancing Cardiomyogenesis Efficiency of hESC Cultures.

Yeo HC, Ting S, Brena RM, Koh G, Chen A, Toh SQ, Lim YM, Oh SK, Lee DY.

Sci Rep. 2016 Aug 9;6:31068. doi: 10.1038/srep31068.


Plasticity underlies tumor progression: role of Nodal signaling.

Bodenstine TM, Chandler GS, Seftor RE, Seftor EA, Hendrix MJ.

Cancer Metastasis Rev. 2016 Mar;35(1):21-39. doi: 10.1007/s10555-016-9605-5.


Conditional Cripto overexpression in satellite cells promotes myogenic commitment and enhances early regeneration.

Prezioso C, Iaconis S, Andolfi G, Zentilin L, Iavarone F, Guardiola O, Minchiotti G.

Front Cell Dev Biol. 2015 May 21;3:31. doi: 10.3389/fcell.2015.00031.


A novel autoregulatory loop between the Gcn2-Atf4 pathway and (L)-Proline [corrected] metabolism controls stem cell identity.

D'Aniello C, Fico A, Casalino L, Guardiola O, Di Napoli G, Cermola F, De Cesare D, Tatè R, Cobellis G, Patriarca EJ, Minchiotti G.

Cell Death Differ. 2015 Jul;22(7):1094-105. doi: 10.1038/cdd.2015.24. Erratum in: Cell Death Differ. 2015 Jul;22(7):1234.


CRIPTO overexpression promotes mesenchymal differentiation in prostate carcinoma cells through parallel regulation of AKT and FGFR activities.

Terry S, El-Sayed IY, Destouches D, Maillé P, Nicolaiew N, Ploussard G, Semprez F, Pimpie C, Beltran H, Londono-Vallejo A, Allory Y, de la Taille A, Salomon DS, Vacherot F.

Oncotarget. 2015 May 20;6(14):11994-2008.


Targeted inactivation of Cerberus like-2 leads to left ventricular cardiac hyperplasia and systolic dysfunction in the mouse.

Araújo AC, Marques S, Belo JA.

PLoS One. 2014 Jul 17;9(7):e102716. doi: 10.1371/journal.pone.0102716.


Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells.

Liu Y, Kaneda R, Leja TW, Subkhankulova T, Tolmachov O, Minchiotti G, Schwartz RJ, Barahona M, Schneider MD.

Stem Cells. 2014 Jun;32(6):1515-26. doi: 10.1002/stem.1695.


Age-Dependent Association between Protein Expression of the Embryonic Stem Cell Marker Cripto-1 and Survival of Glioblastoma Patients.

Tysnes BB, Satran HA, Mork SJ, Margaryan NV, Eide GE, Petersen K, Strizzi L, Hendrix MJ.

Transl Oncol. 2013 Dec 1;6(6):732-41.


L-Proline induces a mesenchymal-like invasive program in embryonic stem cells by remodeling H3K9 and H3K36 methylation.

Comes S, Gagliardi M, Laprano N, Fico A, Cimmino A, Palamidessi A, De Cesare D, De Falco S, Angelini C, Scita G, Patriarca EJ, Matarazzo MR, Minchiotti G.

Stem Cell Reports. 2013 Oct 10;1(4):307-21. doi: 10.1016/j.stemcr.2013.09.001.


Nkx2-5 Regulates Tdgf1 (Cripto) Early During Cardiac Development.

Behrens AN, Ren Y, Ferdous A, Garry DJ, Martin CM.

J Clin Exp Cardiolog. 2012;Suppl 11:1-4.


Advances in retinal stem cell biology.

Viczian AS.

J Ophthalmic Vis Res. 2013 Apr;8(2):147-59.


miR-125b regulates the early steps of ESC differentiation through dies1 in a TGF-independent manner.

Battista M, Musto A, Navarra A, Minopoli G, Russo T, Parisi S.

Int J Mol Sci. 2013 Jun 27;14(7):13482-96. doi: 10.3390/ijms140713482.


Reviewing and updating the major molecular markers for stem cells.

Calloni R, Cordero EA, Henriques JA, Bonatto D.

Stem Cells Dev. 2013 May 1;22(9):1455-76. doi: 10.1089/scd.2012.0637. Review.


Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin.

Guardiola O, Lafuste P, Brunelli S, Iaconis S, Touvier T, Mourikis P, De Bock K, Lonardo E, Andolfi G, Bouché A, Liguori GL, Shen MM, Tajbakhsh S, Cossu G, Carmeliet P, Minchiotti G.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):E3231-40. doi: 10.1073/pnas.1204017109.


A Nodal-to-TGFβ cascade exerts biphasic control over cardiopoiesis.

Cai W, Guzzo RM, Wei K, Willems E, Davidovics H, Mercola M.

Circ Res. 2012 Sep 14;111(7):876-81. doi: 10.1161/CIRCRESAHA.112.270272.


Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors.

Islas JF, Liu Y, Weng KC, Robertson MJ, Zhang S, Prejusa A, Harger J, Tikhomirova D, Chopra M, Iyer D, Mercola M, Oshima RG, Willerson JT, Potaman VN, Schwartz RJ.

Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):13016-21. doi: 10.1073/pnas.1120299109.


Role of Cripto-1 during epithelial-to-mesenchymal transition in development and cancer.

Rangel MC, Karasawa H, Castro NP, Nagaoka T, Salomon DS, Bianco C.

Am J Pathol. 2012 Jun;180(6):2188-200. doi: 10.1016/j.ajpath.2012.02.031. Review.


Cripto/GRP78 modulation of the TGF-β pathway in development and oncogenesis.

Gray PC, Vale W.

FEBS Lett. 2012 Jul 4;586(14):1836-45. doi: 10.1016/j.febslet.2012.01.051. Review.

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