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Items: 1 to 20 of 38


In Vitro Assays for the Functional Characterization of the Dopamine Transporter (DAT).

Aggarwal S, Mortensen OV.

Curr Protoc Pharmacol. 2017 Dec 20;79:12.17.1-12.17.21. doi: 10.1002/cpph.33.


Optimization of a resazurin-based microplate assay for large-scale compound screenings against Klebsiella pneumoniae.

Kim HJ, Jang S.

3 Biotech. 2018 Jan;8(1):3. doi: 10.1007/s13205-017-1034-9. Epub 2017 Dec 7.


Expression and Differential Responsiveness of Central Nervous System Glial Cell Populations to the Acute Phase Protein Serum Amyloid A.

Barbierato M, Borri M, Facci L, Zusso M, Skaper SD, Giusti P.

Sci Rep. 2017 Sep 22;7(1):12158. doi: 10.1038/s41598-017-12529-7.


Designing Drug-Response Experiments and Quantifying their Results.

Hafner M, Niepel M, Subramanian K, Sorger PK.

Curr Protoc Chem Biol. 2017 Jun 19;9(2):96-116. doi: 10.1002/cpch.19.


mQC: A Heuristic Quality-Control Metric for High-Throughput Drug Combination Screening.

Chen L, Wilson K, Goldlust I, Mott BT, Eastman R, Davis MI, Zhang X, McKnight C, Klumpp-Thomas C, Shinn P, Simmons J, Gormally M, Michael S, Thomas CJ, Ferrer M, Guha R.

Sci Rep. 2016 Nov 24;6:37741. doi: 10.1038/srep37741.


Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes.

Bray MA, Singh S, Han H, Davis CT, Borgeson B, Hartland C, Kost-Alimova M, Gustafsdottir SM, Gibson CC, Carpenter AE.

Nat Protoc. 2016 Sep;11(9):1757-74. doi: 10.1038/nprot.2016.105. Epub 2016 Aug 25.


Assay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid Cultures.

Boehnke K, Iversen PW, Schumacher D, Lallena MJ, Haro R, Amat J, Haybaeck J, Liebs S, Lange M, Schäfer R, Regenbrecht CR, Reinhard C, Velasco JA.

J Biomol Screen. 2016 Oct;21(9):931-41. doi: 10.1177/1087057116650965. Epub 2016 May 27.


Identification of thyroid tumor cell vulnerabilities through a siRNA-based functional screening.

Anania M, Gasparri F, Cetti E, Fraietta I, Todoerti K, Miranda C, Mazzoni M, Re C, Colombo R, Ukmar G, Camisasca S, Pagliardini S, Pierotti M, Neri A, Galvani A, Greco A.

Oncotarget. 2015 Oct 27;6(33):34629-48. doi: 10.18632/oncotarget.5282.


The Nucleoside Analog BMS-986001 Shows Greater In Vitro Activity against HIV-2 than against HIV-1.

Smith RA, Raugi DN, Wu VH, Leong SS, Parker KM, Oakes MK, Sow PS, Ba S, Seydi M, Gottlieb GS; University of Washington-Dakar HIV-2 Study Group.

Antimicrob Agents Chemother. 2015 Dec;59(12):7437-46. doi: 10.1128/AAC.01326-15. Epub 2015 Sep 21.


Identification of novel radiosensitizers in a high-throughput, cell-based screen for DSB repair inhibitors.

Goglia AG, Delsite R, Luz AN, Shahbazian D, Salem AF, Sundaram RK, Chiaravalli J, Hendrikx PJ, Wilshire JA, Jasin M, Kluger HM, Glickman JF, Powell SN, Bindra RS.

Mol Cancer Ther. 2015 Feb;14(2):326-42. doi: 10.1158/1535-7163.MCT-14-0765. Epub 2014 Dec 15.


A robust and adaptable high throughput screening method to study host-microbiota interactions in the human intestine.

de Wouters T, Ledue F, Nepelska M, Doré J, Blottière HM, Lapaque N.

PLoS One. 2014 Aug 20;9(8):e105598. doi: 10.1371/journal.pone.0105598. eCollection 2014.


Rapid analysis and exploration of fluorescence microscopy images.

Pavie B, Rajaram S, Ouyang A, Altschuler JM, Steininger RJ 3rd, Wu LF, Altschuler SJ.

J Vis Exp. 2014 Mar 19;(85). doi: 10.3791/51280.


Comprehensive clone screening and evaluation of fed-batch strategies in a microbioreactor and lab scale stirred tank bioreactor system: application on Pichia pastoris producing Rhizopus oryzae lipase.

Hemmerich J, Adelantado N, Barrigón JM, Ponte X, Hörmann A, Ferrer P, Kensy F, Valero F.

Microb Cell Fact. 2014 Mar 7;13(1):36. doi: 10.1186/1475-2859-13-36.


Escherichia coli deletion mutants illuminate trade-offs between growth rate and flux through a foreign anabolic pathway.

Falls KC, Williams AL, Bryksin AV, Matsumura I.

PLoS One. 2014 Feb 4;9(2):e88159. doi: 10.1371/journal.pone.0088159. eCollection 2014.


Viability assays for cells in culture.

Posimo JM, Unnithan AS, Gleixner AM, Choi HJ, Jiang Y, Pulugulla SH, Leak RK.

J Vis Exp. 2014 Jan 20;(83):e50645. doi: 10.3791/50645.


Application of DNA chip scanning technology for automatic detection of Chlamydia trachomatis and Chlamydia pneumoniae inclusions.

Bogdanov A, Endrész V, Urbán S, Lantos I, Deák J, Burián K, Önder K, Ayaydin F, Balázs P, Virok DP.

Antimicrob Agents Chemother. 2014;58(1):405-13. doi: 10.1128/AAC.01400-13. Epub 2013 Nov 4.


Crude and purified proteasome activity assays are affected by type of microplate.

Cui Z, Gilda JE, Gomes AV.

Anal Biochem. 2014 Feb 1;446:44-52. doi: 10.1016/j.ab.2013.10.018. Epub 2013 Oct 17.


Inflammatory stress response in A549 cells as a result of exposure to coal: evidence for the role of pyrite in coal workers' pneumoconiosis pathogenesis.

Harrington AD, Tsirka SE, Schoonen MA.

Chemosphere. 2013 Oct;93(6):1216-21. doi: 10.1016/j.chemosphere.2013.06.082. Epub 2013 Jul 26.


A simple high-content cell cycle assay reveals frequent discrepancies between cell number and ATP and MTS proliferation assays.

Chan GK, Kleinheinz TL, Peterson D, Moffat JG.

PLoS One. 2013 May 17;8(5):e63583. doi: 10.1371/journal.pone.0063583. Print 2013.


Comprehensive Method for Culturing Embryonic Dorsal Root Ganglion Neurons for Seahorse Extracellular Flux XF24 Analysis.

Lange M, Zeng Y, Knight A, Windebank A, Trushina E.

Front Neurol. 2012 Dec 14;3:175. doi: 10.3389/fneur.2012.00175. eCollection 2012.

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