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Items: 1 to 20 of 35

1.

Constitutive Endocytosis of VEGFR2 Protects the Receptor against Shedding.

Basagiannis D, Christoforidis S.

J Biol Chem. 2016 Aug 5;291(32):16892-903. doi: 10.1074/jbc.M116.730309.

PMID:
27298320
2.

ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production.

Sano O, Tsujita M, Shimizu Y, Kato R, Kobayashi A, Kioka N, Remaley AT, Michikawa M, Ueda K, Matsuo M.

PLoS One. 2016 May 19;11(5):e0155400. doi: 10.1371/journal.pone.0155400.

3.

Presenilin 1 and Presenilin 2 Target γ-Secretase Complexes to Distinct Cellular Compartments.

Meckler X, Checler F.

J Biol Chem. 2016 Jun 10;291(24):12821-37. doi: 10.1074/jbc.M115.708297.

PMID:
27059953
4.

High Fat Diet Enhances β-Site Cleavage of Amyloid Precursor Protein (APP) via Promoting β-Site APP Cleaving Enzyme 1/Adaptor Protein 2/Clathrin Complex Formation.

Maesako M, Uemura M, Tashiro Y, Sasaki K, Watanabe K, Noda Y, Ueda K, Asada-Utsugi M, Kubota M, Okawa K, Ihara M, Shimohama S, Uemura K, Kinoshita A.

PLoS One. 2015 Sep 28;10(9):e0131199. doi: 10.1371/journal.pone.0131199.

5.

A novel pathway of cellular activation mediated by antiphospholipid antibody-induced extracellular vesicles.

Wu M, Barnard J, Kundu S, McCrae KR.

J Thromb Haemost. 2015 Oct;13(10):1928-40. doi: 10.1111/jth.13072.

6.

DISC1 regulates trafficking and processing of APP and Aβ generation.

Shahani N, Seshadri S, Jaaro-Peled H, Ishizuka K, Hirota-Tsuyada Y, Wang Q, Koga M, Sedlak TW, Korth C, Brandon NJ, Kamiya A, Subramaniam S, Tomoda T, Sawa A.

Mol Psychiatry. 2015 Jul;20(7):874-9. doi: 10.1038/mp.2014.100.

7.

Sorting nexin 17 regulates ApoER2 recycling and reelin signaling.

Sotelo P, Farfán P, Benitez ML, Bu G, Marzolo MP.

PLoS One. 2014 Apr 4;9(4):e93672. doi: 10.1371/journal.pone.0093672.

8.

Evidence of a novel mechanism for partial γ-secretase inhibition induced paradoxical increase in secreted amyloid β protein.

Barnwell E, Padmaraju V, Baranello R, Pacheco-Quinto J, Crosson C, Ablonczy Z, Eckman E, Eckman CB, Ramakrishnan V, Greig NH, Pappolla MA, Sambamurti K.

PLoS One. 2014 Mar 21;9(3):e91531. doi: 10.1371/journal.pone.0091531.

9.

HIV-1 stimulates nuclear entry of amyloid beta via dynamin dependent EEA1 and TGF-β/Smad signaling.

András IE, Toborek M.

Exp Cell Res. 2014 Apr 15;323(1):66-76. doi: 10.1016/j.yexcr.2014.01.027.

10.

A paired RNAi and RabGAP overexpression screen identifies Rab11 as a regulator of β-amyloid production.

Udayar V, Buggia-Prévot V, Guerreiro RL, Siegel G, Rambabu N, Soohoo AL, Ponnusamy M, Siegenthaler B, Bali J; AESG., Simons M, Ries J, Puthenveedu MA, Hardy J, Thinakaran G, Rajendran L.

Cell Rep. 2013 Dec 26;5(6):1536-51. doi: 10.1016/j.celrep.2013.12.005.

11.

Endolysosome involvement in HIV-1 transactivator protein-induced neuronal amyloid beta production.

Chen X, Hui L, Geiger NH, Haughey NJ, Geiger JD.

Neurobiol Aging. 2013 Oct;34(10):2370-8. doi: 10.1016/j.neurobiolaging.2013.04.015.

12.

Dynamin 1 regulates amyloid generation through modulation of BACE-1.

Zhu L, Su M, Lucast L, Liu L, Netzer WJ, Gandy SE, Cai D.

PLoS One. 2012;7(9):e45033.

13.

Endolysosome involvement in LDL cholesterol-induced Alzheimer's disease-like pathology in primary cultured neurons.

Hui L, Chen X, Geiger JD.

Life Sci. 2012 Dec 10;91(23-24):1159-68. doi: 10.1016/j.lfs.2012.04.039.

14.

Trafficking and proteolytic processing of APP.

Haass C, Kaether C, Thinakaran G, Sisodia S.

Cold Spring Harb Perspect Med. 2012 May;2(5):a006270. doi: 10.1101/cshperspect.a006270. Review.

15.

Adaptor protein 2-mediated endocytosis of the β-secretase BACE1 is dispensable for amyloid precursor protein processing.

Prabhu Y, Burgos PV, Schindler C, Farías GG, Magadán JG, Bonifacino JS.

Mol Biol Cell. 2012 Jun;23(12):2339-51. doi: 10.1091/mbc.E11-11-0944. Erratum in: Mol Biol Cell. 2012 Jul;23(13):2620.

16.

The Membrane-Bound Aspartyl Protease BACE1: Molecular and Functional Properties in Alzheimer's Disease and Beyond.

Dislich B, Lichtenthaler SF.

Front Physiol. 2012 Feb 17;3:8. doi: 10.3389/fphys.2012.00008.

17.

ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1.

Sannerud R, Declerck I, Peric A, Raemaekers T, Menendez G, Zhou L, Veerle B, Coen K, Munck S, De Strooper B, Schiavo G, Annaert W.

Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):E559-68. doi: 10.1073/pnas.1100745108.

18.

Surface expression and limited proteolysis of ADAM10 are increased by a dominant negative inhibitor of dynamin.

Carey RM, Blusztajn JK, Slack BE.

BMC Cell Biol. 2011 May 17;12:20. doi: 10.1186/1471-2121-12-20.

19.

The many substrates of presenilin/γ-secretase.

Haapasalo A, Kovacs DM.

J Alzheimers Dis. 2011;25(1):3-28. doi: 10.3233/JAD-2011-101065. Review.

20.

APP processing in Alzheimer's disease.

Zhang YW, Thompson R, Zhang H, Xu H.

Mol Brain. 2011 Jan 7;4:3. doi: 10.1186/1756-6606-4-3. Review.

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