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Items: 1 to 20 of 93


The V-ATPase is expressed in the choroid plexus and mediates cAMP-induced intracellular pH alterations.

Christensen HL, Păunescu TG, Matchkov V, Barbuskaite D, Brown D, Damkier HH, Praetorius J.

Physiol Rep. 2017 Jan;5(1). pii: e13072. doi: 10.14814/phy2.13072.


Soluble adenylyl cyclase is essential for proper lysosomal acidification.

Rahman N, Ramos-Espiritu L, Milner TA, Buck J, Levin LR.

J Gen Physiol. 2016 Oct;148(4):325-39. doi: 10.1085/jgp.201611606.


Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.

Ramos-Espiritu L, Kleinboelting S, Navarrete FA, Alvau A, Visconti PE, Valsecchi F, Starkov A, Manfredi G, Buck H, Adura C, Zippin JH, van den Heuvel J, Glickman JF, Steegborn C, Levin LR, Buck J.

Nat Chem Biol. 2016 Oct;12(10):838-44. doi: 10.1038/nchembio.2151. Epub 2016 Aug 22.


Nitric oxide and pH modulation in gynaecological cancer.

Sanhueza C, Araos J, Naranjo L, Barros E, Subiabre M, Toledo F, Gutiérrez J, Chiarello DI, Pardo F, Leiva A, Sobrevia L.

J Cell Mol Med. 2016 Dec;20(12):2223-2230. doi: 10.1111/jcmm.12921. Epub 2016 Jul 29. Review.


The Function of V-ATPases in Cancer.

Stransky L, Cotter K, Forgac M.

Physiol Rev. 2016 Jul;96(3):1071-91. doi: 10.1152/physrev.00035.2015. Review.


Aurora kinase A activates the vacuolar H+-ATPase (V-ATPase) in kidney carcinoma cells.

Al-Bataineh MM, Alzamora R, Ohmi K, Ho PY, Marciszyn AL, Gong F, Li H, Hallows KR, Pastor-Soler NM.

Am J Physiol Renal Physiol. 2016 Jun 1;310(11):F1216-28. doi: 10.1152/ajprenal.00061.2016. Epub 2016 Feb 24.


Colocalization of the (Pro)renin Receptor/Atp6ap2 with H+-ATPases in Mouse Kidney but Prorenin Does Not Acutely Regulate Intercalated Cell H+-ATPase Activity.

Daryadel A, Bourgeois S, Figueiredo MF, Gomes Moreira A, Kampik NB, Oberli L, Mohebbi N, Lu X, Meima ME, Danser AH, Wagner CA.

PLoS One. 2016 Jan 29;11(1):e0147831. doi: 10.1371/journal.pone.0147831. eCollection 2016.


Regulation of epithelial function, differentiation, and remodeling in the epididymis.

Breton S, Ruan YC, Park YJ, Kim B.

Asian J Androl. 2016 Jan-Feb;18(1):3-9. doi: 10.4103/1008-682X.165946. Review.


Molecular mechanisms and regulation of urinary acidification.

Kurtz I.

Compr Physiol. 2014 Oct;4(4):1737-74. doi: 10.1002/cphy.c140021. Review.


Role of testicular luminal factors on Basal cell elongation and proliferation in the mouse epididymis.

Kim B, Roy J, Shum WW, Da Silva N, Breton S.

Biol Reprod. 2015 Jan;92(1):9. doi: 10.1095/biolreprod.114.123943. Epub 2014 Nov 19.


Revisiting cAMP signaling in the carotid body.

Nunes AR, Holmes AP, Conde SV, Gauda EB, Monteiro EC.

Front Physiol. 2014 Oct 28;5:406. doi: 10.3389/fphys.2014.00406. eCollection 2014. Review.


Investigation of cAMP microdomains as a path to novel cancer diagnostics.

Desman G, Waintraub C, Zippin JH.

Biochim Biophys Acta. 2014 Dec;1842(12 Pt B):2636-45. doi: 10.1016/j.bbadis.2014.08.016. Epub 2014 Sep 7. Review.


Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function.

Browne JA, Yang R, Song L, Crawford GE, Leir SH, Harris A.

Mol Hum Reprod. 2014 Dec;20(12):1198-207. doi: 10.1093/molehr/gau075. Epub 2014 Sep 1.


Soluble adenylyl cyclase in health and disease.

Schmid A, Meili D, Salathe M.

Biochim Biophys Acta. 2014 Dec;1842(12 Pt B):2584-92. doi: 10.1016/j.bbadis.2014.07.010. Epub 2014 Jul 23. Review.


The role of soluble adenylyl cyclase in neurite outgrowth.

Stiles TL, Kapiloff MS, Goldberg JL.

Biochim Biophys Acta. 2014 Dec;1842(12 Pt B):2561-8. doi: 10.1016/j.bbadis.2014.07.012. Epub 2014 Jul 23. Review.


High-resolution helium ion microscopy of epididymal epithelial cells and their interaction with spermatozoa.

Păunescu TG, Shum WW, Huynh C, Lechner L, Goetze B, Brown D, Breton S.

Mol Hum Reprod. 2014 Oct;20(10):929-37. doi: 10.1093/molehr/gau052. Epub 2014 Jul 11.


Role of the bicarbonate-responsive soluble adenylyl cyclase in pH sensing and metabolic regulation.

Chang JC, Oude-Elferink RP.

Front Physiol. 2014 Feb 10;5:42. doi: 10.3389/fphys.2014.00042. eCollection 2014. Review.


Established and potential physiological roles of bicarbonate-sensing soluble adenylyl cyclase (sAC) in aquatic animals.

Tresguerres M, Barott KL, Barron ME, Roa JN.

J Exp Biol. 2014 Mar 1;217(Pt 5):663-72. doi: 10.1242/jeb.086157. Review.


Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate.

Kleinboelting S, Diaz A, Moniot S, van den Heuvel J, Weyand M, Levin LR, Buck J, Steegborn C.

Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):3727-32. doi: 10.1073/pnas.1322778111. Epub 2014 Feb 24.

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