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Items: 1 to 20 of 257

1.

On the contributing role of the transmembrane domain for subunit-specific sensitivity of integrin activation.

Pagani G, Gohlke H.

Sci Rep. 2018 Apr 10;8(1):5733. doi: 10.1038/s41598-018-23778-5.

2.

Measuring Integrin Conformational Change on the Cell Surface with Super-Resolution Microscopy.

Moore TI, Aaron J, Chew TL, Springer TA.

Cell Rep. 2018 Feb 13;22(7):1903-1912. doi: 10.1016/j.celrep.2018.01.062.

3.

Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation.

Zhu L, Yang J, Bromberger T, Holly A, Lu F, Liu H, Sun K, Klapproth S, Hirbawi J, Byzova TV, Plow EF, Moser M, Qin J.

Nat Commun. 2017 Nov 23;8(1):1744. doi: 10.1038/s41467-017-01822-8.

4.

Energy landscape differences among integrins establish the framework for understanding activation.

Li J, Springer TA.

J Cell Biol. 2018 Jan 2;217(1):397-412. doi: 10.1083/jcb.201701169. Epub 2017 Nov 9.

PMID:
29122968
5.

Extracellular ISG15 Signals Cytokine Secretion through the LFA-1 Integrin Receptor.

Swaim CD, Scott AF, Canadeo LA, Huibregtse JM.

Mol Cell. 2017 Nov 2;68(3):581-590.e5. doi: 10.1016/j.molcel.2017.10.003.

PMID:
29100055
6.

Receptor-mediated cell mechanosensing.

Chen Y, Ju L, Rushdi M, Ge C, Zhu C.

Mol Biol Cell. 2017 Nov 7;28(23):3134-3155. doi: 10.1091/mbc.E17-04-0228. Epub 2017 Sep 27. Review.

7.

A novel intracellular pool of LFA-1 is critical for asymmetric CD8+ T cell activation and differentiation.

Capece T, Walling BL, Lim K, Kim KD, Bae S, Chung HL, Topham DJ, Kim M.

J Cell Biol. 2017 Nov 6;216(11):3817-3829. doi: 10.1083/jcb.201609072. Epub 2017 Sep 27.

PMID:
28954823
8.

α-Actinin Induces a Kink in the Transmembrane Domain of β3-Integrin and Impairs Activation via Talin.

Shams H, Mofrad MRK.

Biophys J. 2017 Aug 22;113(4):948-956. doi: 10.1016/j.bpj.2017.06.064.

PMID:
28834730
9.

Kindlin-2 could influence breast nodule elasticity and improve lymph node metastasis in invasive breast cancer.

Xue X, Li J, Wan W, Shi X, Zheng Y.

Sci Rep. 2017 Jul 28;7(1):6753. doi: 10.1038/s41598-017-07075-1.

10.

LFA-1 activates focal adhesion kinases FAK1/PYK2 to generate LAT-GRB2-SKAP1 complexes that terminate T-cell conjugate formation.

Raab M, Lu Y, Kohler K, Smith X, Strebhardt K, Rudd CE.

Nat Commun. 2017 Jul 12;8:16001. doi: 10.1038/ncomms16001.

11.

Soluble Urokinase Receptor and the Kidney Response in Diabetes Mellitus.

Dande RR, Peev V, Altintas MM, Reiser J.

J Diabetes Res. 2017;2017:3232848. doi: 10.1155/2017/3232848. Epub 2017 May 17. Review.

12.

Structural and mechanical functions of integrins.

Anderson LR, Owens TW, Naylor MJ.

Biophys Rev. 2014 Jun;6(2):203-213. doi: 10.1007/s12551-013-0124-0. Epub 2013 Oct 8. Review.

13.

The endothelin B receptor plays a crucial role in the adhesion of neutrophils to the endothelium in sickle cell disease.

Koehl B, Nivoit P, El Nemer W, Lenoir O, Hermand P, Pereira C, Brousse V, Guyonnet L, Ghinatti G, Benkerrou M, Colin Y, Le Van Kim C, Tharaux PL.

Haematologica. 2017 Jul;102(7):1161-1172. doi: 10.3324/haematol.2016.156869. Epub 2017 Apr 6.

14.

Dynamin2 controls Rap1 activation and integrin clustering in human T lymphocyte adhesion.

Eppler FJ, Quast T, Kolanus W.

PLoS One. 2017 Mar 8;12(3):e0172443. doi: 10.1371/journal.pone.0172443. eCollection 2017.

15.

Conformational equilibria and intrinsic affinities define integrin activation.

Li J, Su Y, Xia W, Qin Y, Humphries MJ, Vestweber D, Cabañas C, Lu C, Springer TA.

EMBO J. 2017 Mar 1;36(5):629-645. doi: 10.15252/embj.201695803. Epub 2017 Jan 25.

16.

Tension in Cancer.

Löffek S, Franzke CW, Helfrich I.

Int J Mol Sci. 2016 Nov 16;17(11). pii: E1910. Review.

17.

Gα13 Switch Region 2 Relieves Talin Autoinhibition to Activate αIIbβ3 Integrin.

Schiemer J, Bohm A, Lin L, Merrill-Skoloff G, Flaumenhaft R, Huang JS, Le Breton GC, Chishti AH.

J Biol Chem. 2016 Dec 23;291(52):26598-26612. doi: 10.1074/jbc.M116.747279. Epub 2016 Nov 1.

18.

Coordinated integrin activation by actin-dependent force during T-cell migration.

Nordenfelt P, Elliott HL, Springer TA.

Nat Commun. 2016 Oct 10;7:13119. doi: 10.1038/ncomms13119.

19.

Tie1 controls angiopoietin function in vascular remodeling and inflammation.

Korhonen EA, Lampinen A, Giri H, Anisimov A, Kim M, Allen B, Fang S, D'Amico G, Sipilä TJ, Lohela M, Strandin T, Vaheri A, Ylä-Herttuala S, Koh GY, McDonald DM, Alitalo K, Saharinen P.

J Clin Invest. 2016 Sep 1;126(9):3495-510. doi: 10.1172/JCI84923. Epub 2016 Aug 22.

20.

Repeated Social Defeat, Neuroinflammation, and Behavior: Monocytes Carry the Signal.

Weber MD, Godbout JP, Sheridan JF.

Neuropsychopharmacology. 2017 Jan;42(1):46-61. doi: 10.1038/npp.2016.102. Epub 2016 Jun 20. Review.

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