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Oxidative stress increases M1dG, a major peroxidation-derived DNA adduct, in mitochondrial DNA.

Wauchope OR, Mitchener MM, Beavers WN, Galligan JJ, Camarillo JM, Sanders WD, Kingsley PJ, Shim HN, Blackwell T, Luong T, deCaestecker M, Fessel JP, Marnett LJ.

Nucleic Acids Res. 2018 Feb 9. doi: 10.1093/nar/gky089. [Epub ahead of print]


Role of Mitochondrial Genome Mutations in Pathogenesis of Carotid Atherosclerosis.

Sazonova MA, Sinyov VV, Ryzhkova AI, Galitsyna EV, Khasanova ZB, Postnov AY, Yarygina EI, Orekhov AN, Sobenin IA.

Oxid Med Cell Longev. 2017;2017:6934394. doi: 10.1155/2017/6934394. Epub 2017 Jul 25.


Mitochondrial toxicity of tobacco smoke and air pollution.

Fetterman JL, Sammy MJ, Ballinger SW.

Toxicology. 2017 Nov 1;391:18-33. doi: 10.1016/j.tox.2017.08.002. Epub 2017 Aug 22. Review. No abstract available.


Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity.

Morrow RM, Picard M, Derbeneva O, Leipzig J, McManus MJ, Gouspillou G, Barbat-Artigas S, Dos Santos C, Hepple RT, Murdock DG, Wallace DC.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2705-2710. doi: 10.1073/pnas.1700997114. Epub 2017 Feb 21.


A Deafness- and Diabetes-associated tRNA Mutation Causes Deficient Pseudouridinylation at Position 55 in tRNAGlu and Mitochondrial Dysfunction.

Wang M, Liu H, Zheng J, Chen B, Zhou M, Fan W, Wang H, Liang X, Zhou X, Eriani G, Jiang P, Guan MX.

J Biol Chem. 2016 Sep 30;291(40):21029-21041. Epub 2016 Aug 12.


Effects of mitochondrial haplogroup N9a on type 2 diabetes mellitus and its associated complications.

Niu Q, Zhang W, Wang H, Guan X, Lu J, Li W.

Exp Ther Med. 2015 Nov;10(5):1918-1924. Epub 2015 Sep 17.


Microhomology-mediated end joining is the principal mediator of double-strand break repair during mitochondrial DNA lesions.

Tadi SK, Sebastian R, Dahal S, Babu RK, Choudhary B, Raghavan SC.

Mol Biol Cell. 2016 Jan 15;27(2):223-35. doi: 10.1091/mbc.E15-05-0260. Epub 2015 Nov 25.


A complex genome-microRNA interplay in human mitochondria.

Shinde S, Bhadra U.

Biomed Res Int. 2015;2015:206382. doi: 10.1155/2015/206382. Epub 2015 Jan 28.


Mitochondrial DNA: impacting central and peripheral nervous systems.

Carelli V, Chan DC.

Neuron. 2014 Dec 17;84(6):1126-42. doi: 10.1016/j.neuron.2014.11.022. Review.


The somatic common deletion in mitochondrial DNA is decreased in schizophrenia.

Mamdani F, Rollins B, Morgan L, Sequeira PA, Vawter MP.

Schizophr Res. 2014 Nov;159(2-3):370-5. doi: 10.1016/j.schres.2014.08.026. Epub 2014 Sep 28.


DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase.

Bharti SK, Sommers JA, Zhou J, Kaplan DL, Spelbrink JN, Mergny JL, Brosh RM Jr.

J Biol Chem. 2014 Oct 24;289(43):29975-93. doi: 10.1074/jbc.M114.567073. Epub 2014 Sep 5.


Mitochondrial metabolism and diabetes.

Kwak SH, Park KS, Lee KU, Lee HK.

J Diabetes Investig. 2010 Oct 19;1(5):161-9. doi: 10.1111/j.2040-1124.2010.00047.x. Review.


Mitochondrial-nuclear genome interactions in non-alcoholic fatty liver disease in mice.

Betancourt AM, King AL, Fetterman JL, Millender-Swain T, Finley RD, Oliva CR, Crowe DR, Ballinger SW, Bailey SM.

Biochem J. 2014 Jul 15;461(2):223-32. doi: 10.1042/BJ20131433.


mtDNA Mutations and Their Role in Aging, Diseases and Forensic Sciences.

Zapico SC, Ubelaker DH.

Aging Dis. 2013 Oct 3;4(6):364-80. doi: 10.14336/AD.2013.0400364. Review.


Mitochondrial DNA genetics and the heteroplasmy conundrum in evolution and disease.

Wallace DC, Chalkia D.

Cold Spring Harb Perspect Biol. 2013 Nov 1;5(11):a021220. doi: 10.1101/cshperspect.a021220. Review.


Molecular and clinical characterization of the variable phenotype in Korean families with hearing loss associated with the mitochondrial A1555G mutation.

Bae JW, Kim DB, Choi JY, Park HJ, Lee JD, Hur DG, Bae SH, Jung DJ, Lee SH, Kim UK, Lee KY.

PLoS One. 2012;7(8):e42463. doi: 10.1371/journal.pone.0042463. Epub 2012 Aug 6.


The 12S rRNA A1555G mutation in the mitochondrial haplogroup D5a is responsible for maternally inherited hypertension and hearing loss in two Chinese pedigrees.

Chen H, Zheng J, Xue L, Meng Y, Wang Y, Zheng B, Fang F, Shi S, Qiu Q, Jiang P, Lu Z, Mo JQ, Lu J, Guan MX.

Eur J Hum Genet. 2012 Jun;20(6):607-12. doi: 10.1038/ejhg.2011.259. Epub 2012 Feb 8.


Mitochondrial dysfunction and β-cell failure in type 2 diabetes mellitus.

Ma ZA, Zhao Z, Turk J.

Exp Diabetes Res. 2012;2012:703538. doi: 10.1155/2012/703538. Epub 2011 Nov 9. Review.

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