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Items: 1 to 20 of 38


The Signature of MicroRNA Dysregulation in Muscle Paralyzed by Spinal Cord Injury Includes Downregulation of MicroRNAs that Target Myostatin Signaling.

De Gasperi R, Graham ZA, Harlow LM, Bauman WA, Qin W, Cardozo CP.

PLoS One. 2016 Dec 1;11(12):e0166189. doi: 10.1371/journal.pone.0166189. eCollection 2016.


Curcumin slows osteoarthritis progression and relieves osteoarthritis-associated pain symptoms in a post-traumatic osteoarthritis mouse model.

Zhang Z, Leong DJ, Xu L, He Z, Wang A, Navati M, Kim SJ, Hirsh DM, Hardin JA, Cobelli NJ, Friedman JM, Sun HB.

Arthritis Res Ther. 2016 Jun 3;18(1):128. doi: 10.1186/s13075-016-1025-y.


Moderate Exercise Mitigates the Detrimental Effects of Aging on Tendon Stem Cells.

Zhang J, Wang JH.

PLoS One. 2015 Jun 18;10(6):e0130454. doi: 10.1371/journal.pone.0130454. eCollection 2015.


The role of cyclooxygenase-2, interleukin-1β and fibroblast growth factor-2 in the activation of matrix metalloproteinase-1 in sheared-chondrocytes and articular cartilage.

Guan PP, Guo JW, Yu X, Wang Y, Wang T, Konstantopoulos K, Wang ZY, Wang P.

Sci Rep. 2015 May 20;5:10412. doi: 10.1038/srep10412.


Estrogen receptor beta and truncated variants enhance the expression of transfected MMP-1 promoter constructs in response to specific mechanical loading.

Thaler JD, Achari Y, Lu T, Shrive NG, Hart DA.

Biol Sex Differ. 2014 Sep 27;5:14. doi: 10.1186/s13293-014-0014-6. eCollection 2014.


Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse post-traumatic osteoarthritis model.

Leong DJ, Choudhury M, Hanstein R, Hirsh DM, Kim SJ, Majeska RJ, Schaffler MB, Hardin JA, Spray DC, Goldring MB, Cobelli NJ, Sun HB.

Arthritis Res Ther. 2014 Dec 17;16(6):508. doi: 10.1186/s13075-014-0508-y.


Distinctive subcellular inhibition of cytokine-induced SRC by salubrinal and fluid flow.

Wan Q, Xu W, Yan JL, Yokota H, Na S.

PLoS One. 2014 Aug 26;9(8):e105699. doi: 10.1371/journal.pone.0105699. eCollection 2014.


Mechanical loading: potential preventive and therapeutic strategy for osteoarthritis.

Leong DJ, Sun HB.

J Am Acad Orthop Surg. 2014 Jul;22(7):465-6. doi: 10.5435/JAAOS-22-07-465. No abstract available.


Human dendritic cells exhibit a pronounced type I IFN signature following Leishmania major infection that is required for IL-12 induction.

Favila MA, Geraci NS, Zeng E, Harker B, Condon D, Cotton RN, Jayakumar A, Tripathi V, McDowell MA.

J Immunol. 2014 Jun 15;192(12):5863-72. doi: 10.4049/jimmunol.1203230. Epub 2014 May 7.


Knee loading reduces MMP13 activity in the mouse cartilage.

Hamamura K, Zhang P, Zhao L, Shim JW, Chen A, Dodge TR, Wan Q, Shih H, Na S, Lin CC, Sun HB, Yokota H.

BMC Musculoskelet Disord. 2013 Nov 1;14:312. doi: 10.1186/1471-2474-14-312.


Fluid shear stress-induced osteoarthritis: roles of cyclooxygenase-2 and its metabolic products in inducing the expression of proinflammatory cytokines and matrix metalloproteinases.

Wang P, Guan PP, Guo C, Zhu F, Konstantopoulos K, Wang ZY.

FASEB J. 2013 Dec;27(12):4664-77. doi: 10.1096/fj.13-234542. Epub 2013 Aug 20. Review.


Shear stress modulates macrophage-induced urokinase plasminogen activator expression in human chondrocytes.

Yeh CC, Chang SF, Huang TY, Chang HI, Kuo HC, Wu YC, Hsieh CH, Shi CS, Chen CN.

Arthritis Res Ther. 2013 Apr 18;15(2):R53. doi: 10.1186/ar4215.


Computational and experimental models of cancer cell response to fluid shear stress.

Mitchell MJ, King MR.

Front Oncol. 2013 Mar 5;3:44. doi: 10.3389/fonc.2013.00044. eCollection 2013.


Dynamic compression of chondrocyte-agarose constructs reveals new candidate mechanosensitive genes.

Bougault C, Aubert-Foucher E, Paumier A, Perrier-Groult E, Huot L, Hot D, Duterque-Coquillaud M, Mallein-Gerin F.

PLoS One. 2012;7(5):e36964. doi: 10.1371/journal.pone.0036964. Epub 2012 May 17.


Effect of the glycocalyx layer on transmission of interstitial flow shear stress to embedded cells.

Tarbell JM, Shi ZD.

Biomech Model Mechanobiol. 2013 Jan;12(1):111-21. doi: 10.1007/s10237-012-0385-8. Epub 2012 Mar 13.


Mechanotransduction and cartilage integrity.

Leong DJ, Hardin JA, Cobelli NJ, Sun HB.

Ann N Y Acad Sci. 2011 Dec;1240:32-7. doi: 10.1111/j.1749-6632.2011.06301.x. Review.


Moderate joint loading reduces degenerative actions of matrix metalloproteinases in the articular cartilage of mouse ulnae.

Sun HB, Zhao L, Tanaka S, Yokota H.

Connect Tissue Res. 2012;53(2):180-6. doi: 10.3109/03008207.2011.628765. Epub 2011 Dec 7.


Biomechanical influence of cartilage homeostasis in health and disease.

Bader DL, Salter DM, Chowdhury TT.

Arthritis. 2011;2011:979032. doi: 10.1155/2011/979032. Epub 2011 Sep 15.


Mechanical intervention for maintenance of cartilage and bone.

Sun HB, Cardoso L, Yokota H.

Clin Med Insights Arthritis Musculoskelet Disord. 2011;4:65-70. doi: 10.4137/CMAMD.S6982. Epub 2011 Jun 29.

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