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Items: 1 to 20 of 28


Relaxin-like peptides in male reproduction - a human perspective.

Ivell R, Agoulnik AI, Anand-Ivell R.

Br J Pharmacol. 2017 May;174(10):990-1001. doi: 10.1111/bph.13689. Epub 2017 Feb 27. Review.


Synthetic non-peptide low molecular weight agonists of the relaxin receptor 1.

Agoulnik AI, Agoulnik IU, Hu X, Marugan J.

Br J Pharmacol. 2017 May;174(10):977-989. doi: 10.1111/bph.13656. Epub 2016 Nov 30. Review.


Relaxin and insulin-like peptide 3 in the musculoskeletal system: from bench to bedside.

Ferlin A, De Toni L, Sandri M, Foresta C.

Br J Pharmacol. 2017 May;174(10):1015-1024. doi: 10.1111/bph.13490. Epub 2016 May 5. Review.


Structural Insights into the Activation of Human Relaxin Family Peptide Receptor 1 by Small-Molecule Agonists.

Hu X, Myhr C, Huang Z, Xiao J, Barnaeva E, Ho BA, Agoulnik IU, Ferrer M, Marugan JJ, Southall N, Agoulnik AI.

Biochemistry. 2016 Mar 29;55(12):1772-83. doi: 10.1021/acs.biochem.5b01195. Epub 2016 Mar 4.


Diethylstilbestrol Regulates the Expression of LGR8 in Mouse Gubernaculum Testis Cells.

Duan S, Jiang X, Zhang X, Xie L, Sun Z, Ma S, Li J.

Med Sci Monit. 2016 Feb 8;22:416-21.


An insight into insulin-like factor 3 regulate its receptor RXFP2 in mouse gubernaculum testis cells.

Duan S, Zhang X, Jiang X, Xie L, Sun Z, Ma S, Li J.

Int J Clin Exp Pathol. 2015 Nov 1;8(11):14806-11. eCollection 2015.


Synthesis of fluorescent analogs of relaxin family peptides and their preliminary in vitro and in vivo characterization.

Chan LJ, Smith CM, Chua BE, Lin F, Bathgate RA, Separovic F, Gundlach AL, Hossain MA, Wade JD.

Front Chem. 2013 Dec 6;1:30. doi: 10.3389/fchem.2013.00030. eCollection 2013.


The fate of spermatogonial stem cells in the cryptorchid testes of RXFP2 deficient mice.

Ferguson L, How JJ, Agoulnik AI.

PLoS One. 2013 Oct 3;8(10):e77351. doi: 10.1371/journal.pone.0077351. eCollection 2013.


Identification of small-molecule agonists of human relaxin family receptor 1 (RXFP1) by using a homogenous cell-based cAMP assay.

Chen CZ, Southall N, Xiao J, Marugan JJ, Ferrer M, Hu X, Jones RE, Feng S, Agoulnik IU, Zheng W, Agoulnik AI.

J Biomol Screen. 2013 Jul;18(6):670-7. doi: 10.1177/1087057112469406. Epub 2012 Dec 4.


Relaxin induces matrix-metalloproteinases-9 and -13 via RXFP1: induction of MMP-9 involves the PI3K, ERK, Akt and PKC-ζ pathways.

Ahmad N, Wang W, Nair R, Kapila S.

Mol Cell Endocrinol. 2012 Nov 5;363(1-2):46-61. doi: 10.1016/j.mce.2012.07.006. Epub 2012 Jul 24.


INSL3 in the ruminant: a powerful indicator of gender- and genetic-specific feto-maternal dialogue.

Anand-Ivell R, Hiendleder S, Viñoles C, Martin GB, Fitzsimmons C, Eurich A, Hafen B, Ivell R.

PLoS One. 2011;6(5):e19821. doi: 10.1371/journal.pone.0019821. Epub 2011 May 16.


Uterine cysts in female mice deficient for caveolin-1 and insulin-like 3 receptor RXFP2.

Li Z, Feng S, Lopez V, Elhammady G, Anderson ML, Kaftanovskaya EM, Agoulnik AI.

Endocrinology. 2011 Jun;152(6):2474-82. doi: 10.1210/en.2010-1015. Epub 2011 Apr 5.


Mendelian genetics of male infertility.

Hwang K, Yatsenko AN, Jorgez CJ, Mukherjee S, Nalam RL, Matzuk MM, Lamb DJ.

Ann N Y Acad Sci. 2010 Dec;1214:E1-E17. doi: 10.1111/j.1749-6632.2010.05917.x. Review.


Suppression of insulin-like3 receptor reveals the role of β-catenin and Notch signaling in gubernaculum development.

Kaftanovskaya EM, Feng S, Huang Z, Tan Y, Barbara AM, Kaur S, Truong A, Gorlov IP, Agoulnik AI.

Mol Endocrinol. 2011 Jan;25(1):170-83. doi: 10.1210/me.2010-0330. Epub 2010 Dec 8.


Expression of insulin-like 3 (INSL3) and differential splicing of its receptor in the ovary of rhesus macaques.

Hanna CB, Yao S, Patta MC, Jensen JT, Wu X.

Reprod Biol Endocrinol. 2010 Dec 7;8:150. doi: 10.1186/1477-7827-8-150.


Insulin-like 3 exposure of the fetal rat gubernaculum modulates expression of genes involved in neural pathways.

Johnson KJ, Robbins AK, Wang Y, McCahan SM, Chacko JK, Barthold JS.

Biol Reprod. 2010 Nov;83(5):774-82. doi: 10.1095/biolreprod.110.085175. Epub 2010 Jul 14.


Relaxin signaling activates peroxisome proliferator-activated receptor gamma.

Singh S, Bennett RG.

Mol Cell Endocrinol. 2010 Feb 5;315(1-2):239-45. doi: 10.1016/j.mce.2009.08.014. Epub 2009 Aug 25.


INSL3/RXFP2 signaling in testicular descent.

Feng S, Ferlin A, Truong A, Bathgate R, Wade JD, Corbett S, Han S, Tannour-Louet M, Lamb DJ, Foresta C, Agoulnik AI.

Ann N Y Acad Sci. 2009 Apr;1160:197-204. doi: 10.1111/j.1749-6632.2009.03841.x. Review.


Fetal Leydig cell origin and development.

Griswold SL, Behringer RR.

Sex Dev. 2009;3(1):1-15. doi: 10.1159/000200077. Epub 2009 Apr 1. Review.


Characterization of relaxin receptor (RXFP1) desensitization and internalization in primary human decidual cells and RXFP1-transfected HEK293 cells.

Kern A, Bryant-Greenwood GD.

Endocrinology. 2009 May;150(5):2419-28. doi: 10.1210/en.2008-1385. Epub 2008 Dec 30.

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