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Items: 1 to 20 of 34


Reconstitution of the complete pathway of ITS2 processing at the pre-ribosome.

Fromm L, Falk S, Flemming D, Schuller JM, Thoms M, Conti E, Hurt E.

Nat Commun. 2017 Nov 27;8(1):1787. doi: 10.1038/s41467-017-01786-9.


Identification of karyopherins involved in the nuclear import of RNA exosome subunit Rrp6 in Saccharomyces cerevisiae.

Gonzales-Zubiate FA, Okuda EK, Da Cunha JPC, Oliveira CC.

J Biol Chem. 2017 Jul 21;292(29):12267-12284. doi: 10.1074/jbc.M116.772376. Epub 2017 May 24.


The Rrp6 C-terminal domain binds RNA and activates the nuclear RNA exosome.

Wasmuth EV, Lima CD.

Nucleic Acids Res. 2017 Jan 25;45(2):846-860. doi: 10.1093/nar/gkw1152. Epub 2016 Nov 29.


Relative contributions of the structural and catalytic roles of Rrp6 in exosomal degradation of individual mRNAs.

Mukherjee K, Gardin J, Futcher B, Leatherwood J.

RNA. 2016 Sep;22(9):1311-9. doi: 10.1261/rna.051490.115. Epub 2016 Jul 11.


Structure and Activities of the Eukaryotic RNA Exosome.

Wasmuth EV, Lima CD.

Enzymes. 2012;31:53-75. doi: 10.1016/B978-0-12-404740-2.00003-3. Epub 2012 Sep 29.


An Interaction between RRP6 and SU(VAR)3-9 Targets RRP6 to Heterochromatin and Contributes to Heterochromatin Maintenance in Drosophila melanogaster.

Eberle AB, Jordán-Pla A, Gañez-Zapater A, Hessle V, Silberberg G, von Euler A, Silverstein RA, Visa N.

PLoS Genet. 2015 Sep 21;11(9):e1005523. doi: 10.1371/journal.pgen.1005523. eCollection 2015 Sep.


Nab3 facilitates the function of the TRAMP complex in RNA processing via recruitment of Rrp6 independent of Nrd1.

Fasken MB, Laribee RN, Corbett AH.

PLoS Genet. 2015 Mar 16;11(3):e1005044. doi: 10.1371/journal.pgen.1005044. eCollection 2015 Mar.


Poly(A) tail-mediated gene regulation by opposing roles of Nab2 and Pab2 nuclear poly(A)-binding proteins in pre-mRNA decay.

Grenier St-Sauveur V, Soucek S, Corbett AH, Bachand F.

Mol Cell Biol. 2013 Dec;33(23):4718-31. doi: 10.1128/MCB.00887-13. Epub 2013 Sep 30.


Assembly of the yeast exoribonuclease Rrp6 with its associated cofactor Rrp47 occurs in the nucleus and is critical for the controlled expression of Rrp47.

Feigenbutz M, Jones R, Besong TM, Harding SE, Mitchell P.

J Biol Chem. 2013 May 31;288(22):15959-70. doi: 10.1074/jbc.M112.445759. Epub 2013 Apr 11.


Ski2-like RNA helicase structures: common themes and complex assemblies.

Johnson SJ, Jackson RN.

RNA Biol. 2013 Jan;10(1):33-43. doi: 10.4161/rna.22101. Epub 2012 Sep 20. Review.


Air proteins control differential TRAMP substrate specificity for nuclear RNA surveillance.

Schmidt K, Xu Z, Mathews DH, Butler JS.

RNA. 2012 Oct;18(10):1934-45. doi: 10.1261/rna.033431.112. Epub 2012 Aug 24.


Activities of human RRP6 and structure of the human RRP6 catalytic domain.

Januszyk K, Liu Q, Lima CD.

RNA. 2011 Aug;17(8):1566-77. doi: 10.1261/rna.2763111. Epub 2011 Jun 24.


Structural components and architectures of RNA exosomes.

Januszyk K, Lima CD.

Adv Exp Med Biol. 2010;702:9-28. Review.


A novel member of the RNase D exoribonuclease family functions in mitochondrial guide RNA metabolism in Trypanosoma brucei.

Zimmer SL, McEvoy SM, Li J, Qu J, Read LK.

J Biol Chem. 2011 Mar 25;286(12):10329-40. doi: 10.1074/jbc.M110.152439. Epub 2011 Jan 20.


Execution of the meiotic noncoding RNA expression program and the onset of gametogenesis in yeast require the conserved exosome subunit Rrp6.

Lardenois A, Liu Y, Walther T, Chalmel F, Evrard B, Granovskaia M, Chu A, Davis RW, Steinmetz LM, Primig M.

Proc Natl Acad Sci U S A. 2011 Jan 18;108(3):1058-63. doi: 10.1073/pnas.1016459108. Epub 2010 Dec 13.


TRAMP complex enhances RNA degradation by the nuclear exosome component Rrp6.

Callahan KP, Butler JS.

J Biol Chem. 2010 Feb 5;285(6):3540-7. doi: 10.1074/jbc.M109.058396. Epub 2009 Dec 2.


Regulation of NAB2 mRNA 3'-end formation requires the core exosome and the Trf4p component of the TRAMP complex.

Roth KM, Byam J, Fang F, Butler JS.

RNA. 2009 Jun;15(6):1045-58. doi: 10.1261/rna.709609. Epub 2009 Apr 15.


Interdependent nucleocytoplasmic trafficking and interactions of Dis3 with Rrp6, the core exosome and importin-alpha3.

Graham AC, Davis SM, Andrulis ED.

Traffic. 2009 May;10(5):499-513. doi: 10.1111/j.1600-0854.2009.00888.x. Epub 2009 Feb 11.


Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.

Callahan KP, Butler JS.

Nucleic Acids Res. 2008 Dec;36(21):6645-55. doi: 10.1093/nar/gkn743. Epub 2008 Oct 21.

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