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Items: 15


XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A.

Miyake T, Pradeep S, Wu SY, Rupaimoole R, Zand B, Wen Y, Gharpure KM, Nagaraja AS, Hu W, Cho MS, Dalton HJ, Previs RA, Taylor ML, Hisamatsu T, Kang Y, Liu T, Shacham S, McCauley D, Hawke DH, Wiktorowicz JE, Coleman RL, Sood AK.

Clin Cancer Res. 2015 Jul 15;21(14):3286-97. doi: 10.1158/1078-0432.CCR-14-1953. Epub 2015 Apr 15.


Two Isoforms of the RNA Binding Protein, Coding Region Determinant-binding Protein (CRD-BP/IGF2BP1), Are Expressed in Breast Epithelium and Support Clonogenic Growth of Breast Tumor Cells.

Fakhraldeen SA, Clark RJ, Roopra A, Chin EN, Huang W, Castorino J, Wisinski KB, Kim T, Spiegelman VS, Alexander CM.

J Biol Chem. 2015 May 22;290(21):13386-400. doi: 10.1074/jbc.M115.655175. Epub 2015 Apr 10.


Molecular insights into the coding region determinant-binding protein-RNA interaction through site-directed mutagenesis in the heterogeneous nuclear ribonucleoprotein-K-homology domains.

Barnes M, van Rensburg G, Li WM, Mehmood K, Mackedenski S, Chan CM, King DT, Miller AL, Lee CH.

J Biol Chem. 2015 Jan 2;290(1):625-39. doi: 10.1074/jbc.M114.614735. Epub 2014 Nov 11.


Immunohistochemical expression of IMP3 and p53 in inflammatory lesions and neoplastic lesions of the gastric mucosa.

Strehl JD, Hoegel J, Hornicek I, Hartmann A, Riener MO.

Int J Clin Exp Pathol. 2014 Apr 15;7(5):2091-101. eCollection 2014.


Humoral autoimmune responses to insulin-like growth factor II mRNA-binding proteins IMP1 and p62/IMP2 in ovarian cancer.

Liu X, Ye H, Li L, Li W, Zhang Y, Zhang JY.

J Immunol Res. 2014;2014:326593. doi: 10.1155/2014/326593. Epub 2014 Apr 27.


Oncogenic NRAS, required for pathogenesis of embryonic rhabdomyosarcoma, relies upon the HMGA2-IGF2BP2 pathway.

Li Z, Zhang Y, Ramanujan K, Ma Y, Kirsch DG, Glass DJ.

Cancer Res. 2013 May 15;73(10):3041-50. doi: 10.1158/0008-5472.CAN-12-3947. Epub 2013 Mar 27.


The rs11705701 G>A polymorphism of IGF2BP2 is associated with IGF2BP2 mRNA and protein levels in the visceral adipose tissue - a link to type 2 diabetes susceptibility.

Chistiakov DA, Nikitin AG, Smetanina SA, Bel'chikova LN, Suplotova LA, Shestakova MV, Nosikov VV.

Rev Diabet Stud. 2012 Summer-Fall;9(2-3):112-22. doi: 10.1900/RDS.2012.9.112. Epub 2012 Nov 15.


Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?

Bell JL, Wächter K, Mühleck B, Pazaitis N, Köhn M, Lederer M, Hüttelmaier S.

Cell Mol Life Sci. 2013 Aug;70(15):2657-75. doi: 10.1007/s00018-012-1186-z. Epub 2012 Oct 16. Review.


KH domains with impaired nucleic acid binding as a tool for functional analysis.

Hollingworth D, Candel AM, Nicastro G, Martin SR, Briata P, Gherzi R, Ramos A.

Nucleic Acids Res. 2012 Aug;40(14):6873-86. doi: 10.1093/nar/gks368. Epub 2012 Apr 29.


The zipcode-binding protein ZBP1 influences the subcellular location of the Ro 60-kDa autoantigen and the noncoding Y3 RNA.

Sim S, Yao J, Weinberg DE, Niessen S, Yates JR 3rd, Wolin SL.

RNA. 2012 Jan;18(1):100-10. doi: 10.1261/rna.029207.111. Epub 2011 Nov 23.


Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1.

Boyerinas B, Park SM, Murmann AE, Gwin K, Montag AG, Zillhardt M, Hua YJ, Lengyel E, Peter ME.

Int J Cancer. 2012 Apr 15;130(8):1787-97. doi: 10.1002/ijc.26190. Epub 2011 Aug 16.


Nucleocytoplasmic traffic of CPEB1 and accumulation in Crm1 nucleolar bodies.

Ernoult-Lange M, Wilczynska A, Harper M, Aigueperse C, Dautry F, Kress M, Weil D.

Mol Biol Cell. 2009 Jan;20(1):176-87. doi: 10.1091/mbc.E08-09-0904. Epub 2008 Oct 15.


RNA-binding IMPs promote cell adhesion and invadopodia formation.

Vikesaa J, Hansen TV, Jønson L, Borup R, Wewer UM, Christiansen J, Nielsen FC.

EMBO J. 2006 Apr 5;25(7):1456-68. Epub 2006 Mar 16.


Sequential dimerization of human zipcode-binding protein IMP1 on RNA: a cooperative mechanism providing RNP stability.

Nielsen J, Kristensen MA, Willemoës M, Nielsen FC, Christiansen J.

Nucleic Acids Res. 2004 Aug 16;32(14):4368-76. Print 2004.


Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice.

Hansen TV, Hammer NA, Nielsen J, Madsen M, Dalbaeck C, Wewer UM, Christiansen J, Nielsen FC.

Mol Cell Biol. 2004 May;24(10):4448-64.

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