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RCC2 over-expression in tumor cells alters apoptosis and drug sensitivity by regulating Rac1 activation.

Wu N, Ren D, Li S, Ma W, Hu S, Jin Y, Xiao S.

BMC Cancer. 2018 Jan 10;18(1):67. doi: 10.1186/s12885-017-3908-y.


RCC2 is a novel p53 target in suppressing metastasis.

Song C, Liang L, Jin Y, Li Y, Liu Y, Guo L, Wu C, Yun CH, Yin Y.

Oncogene. 2018 Jan 4;37(1):8-17. doi: 10.1038/onc.2017.306. Epub 2017 Sep 4.


The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells.

Nötzold L, Frank L, Gandhi M, Polycarpou-Schwarz M, Groß M, Gunkel M, Beil N, Erfle H, Harder N, Rohr K, Trendel J, Krijgsveld J, Longerich T, Schirmacher P, Boutros M, Erhardt S, Diederichs S.

Sci Rep. 2017 May 23;7(1):2265. doi: 10.1038/s41598-017-02357-0.


Epigenetically altered miR-1247 functions as a tumor suppressor in pancreatic cancer.

Yi JM, Kang EJ, Kwon HM, Bae JH, Kang K, Ahuja N, Yang K.

Oncotarget. 2017 Apr 18;8(16):26600-26612. doi: 10.18632/oncotarget.15722.


The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling.

Krenn V, Musacchio A.

Front Oncol. 2015 Oct 16;5:225. doi: 10.3389/fonc.2015.00225. eCollection 2015. Review.


TD-60 links RalA GTPase function to the CPC in mitosis.

Papini D, Langemeyer L, Abad MA, Kerr A, Samejima I, Eyers PA, Jeyaprakash AA, Higgins JM, Barr FA, Earnshaw WC.

Nat Commun. 2015 Jul 9;6:7678. doi: 10.1038/ncomms8678.


Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure.

Williamson RC, Cowell CA, Hammond CL, Bergen DJ, Roper JA, Feng Y, Rendall TC, Race PR, Bass MD.

J Cell Sci. 2014 Oct 1;127(Pt 19):4292-307. doi: 10.1242/jcs.154864. Epub 2014 Jul 29.


EB1 enables spindle microtubules to regulate centromeric recruitment of Aurora B.

Banerjee B, Kestner CA, Stukenberg PT.

J Cell Biol. 2014 Mar 17;204(6):947-63. doi: 10.1083/jcb.201307119. Epub 2014 Mar 10.


Melanoma risk loci as determinants of melanoma recurrence and survival.

Rendleman J, Shang S, Dominianni C, Shields JF, Scanlon P, Adaniel C, Desrichard A, Ma M, Shapiro R, Berman R, Pavlick A, Polsky D, Shao Y, Osman I, Kirchhoff T.

J Transl Med. 2013 Nov 4;11:279. doi: 10.1186/1479-5876-11-279.


Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway.

Jacquemet G, Morgan MR, Byron A, Humphries JD, Choi CK, Chen CS, Caswell PT, Humphries MJ.

J Cell Sci. 2013 Sep 15;126(Pt 18):4121-35. doi: 10.1242/jcs.121988. Epub 2013 Jul 10.


MiR-29c is downregulated in gastric carcinomas and regulates cell proliferation by targeting RCC2.

Matsuo M, Nakada C, Tsukamoto Y, Noguchi T, Uchida T, Hijiya N, Matsuura K, Moriyama M.

Mol Cancer. 2013 Feb 25;12:15. doi: 10.1186/1476-4598-12-15.


TD-60 is required for interphase cell cycle progression.

Yenjerla M, Panopoulos A, Reynaud C, Fotedar R, Margolis RL.

Cell Cycle. 2013 Mar 1;12(5):837-41. doi: 10.4161/cc.23821. Epub 2013 Feb 6.


A microRNA network regulates proliferative timing and extracellular matrix synthesis during cellular quiescence in fibroblasts.

Suh EJ, Remillard MY, Legesse-Miller A, Johnson EL, Lemons JM, Chapman TR, Forman JJ, Kojima M, Silberman ES, Coller HA.

Genome Biol. 2012 Dec 22;13(12):R121. doi: 10.1186/gb-2012-13-12-r121.


The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis.

Carmena M, Wheelock M, Funabiki H, Earnshaw WC.

Nat Rev Mol Cell Biol. 2012 Dec;13(12):789-803. doi: 10.1038/nrm3474. Review.


Phosphoinositide 3-kinase β regulates chromosome segregation in mitosis.

Silió V, Redondo-Muñoz J, Carrera AC.

Mol Biol Cell. 2012 Dec;23(23):4526-42. doi: 10.1091/mbc.E12-05-0371. Epub 2012 Oct 10.


A novel mutation causing nephronophthisis in the Lewis polycystic kidney rat localises to a conserved RCC1 domain in Nek8.

McCooke JK, Appels R, Barrero RA, Ding A, Ozimek-Kulik JE, Bellgard MI, Morahan G, Phillips JK.

BMC Genomics. 2012 Aug 16;13:393. doi: 10.1186/1471-2164-13-393.


Alternative cellular roles for proteins identified using proteomics.

Byron A, Humphries JD, Humphries MJ.

J Proteomics. 2012 Jul 16;75(13):4184-5. doi: 10.1016/j.jprot.2012.04.049. Epub 2012 May 9. No abstract available.


Mass spectrometric analysis identifies a cortactin-RCC2/TD60 interaction in mitotic cells.

Grigera PR, Ma L, Borgman CA, Pinto AF, Sherman NE, Parsons JT, Fox JW.

J Proteomics. 2012 Apr 3;75(7):2153-9. doi: 10.1016/j.jprot.2012.01.012. Epub 2012 Jan 17.


Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins.

Carmena M, Ruchaud S, Earnshaw WC.

Curr Opin Cell Biol. 2009 Dec;21(6):796-805. doi: 10.1016/ Review.


Binding partner switching on microtubules and aurora-B in the mitosis to cytokinesis transition.

Ozlü N, Monigatti F, Renard BY, Field CM, Steen H, Mitchison TJ, Steen JJ.

Mol Cell Proteomics. 2010 Feb;9(2):336-50. doi: 10.1074/mcp.M900308-MCP200. Epub 2009 Sep 28.

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