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Hedgehog Signaling in Pancreatic Fibrosis and Cancer.

Bai Y, Bai Y, Dong J, Li Q, Jin Y, Chen B, Zhou M.

Medicine (Baltimore). 2016 Mar;95(10):e2996. doi: 10.1097/MD.0000000000002996. Review.


Activation of SHH signaling pathway promotes vasculogenesis in post-myocardial ischemic-reperfusion injury.

Guo W, Yi X, Ren F, Liu L, Wu S, Yang J.

Int J Clin Exp Pathol. 2015 Oct 1;8(10):12464-72. eCollection 2015.


A novel function of the human oncogene Stil: Regulation of PC12 cell toxic susceptibility through the Shh pathway.

Li L, Carr AL, Sun L, Drewing A, Lee J, Rao Z.

Sci Rep. 2015 Nov 9;5:16513. doi: 10.1038/srep16513.


Regulation of Hedgehog signaling by ubiquitination.

Hsia EY, Gui Y, Zheng X.

Front Biol (Beijing). 2015 Jun;10(3):203-220.


Hedgehog regulates cerebellar progenitor cell and medulloblastoma apoptosis.

Noguchi KK, Cabrera OH, Swiney BS, Salinas-Contreras P, Smith JK, Farber NB.

Neurobiol Dis. 2015 Nov;83:35-43. doi: 10.1016/j.nbd.2015.08.020. Epub 2015 Aug 28.


Hedgehog Signaling in the Maintenance of Cancer Stem Cells.

Cochrane CR, Szczepny A, Watkins DN, Cain JE.

Cancers (Basel). 2015 Aug 11;7(3):1554-85. doi: 10.3390/cancers7030851. Review.


Kremen1 and Dickkopf1 control cell survival in a Wnt-independent manner.

Causeret F, Sumia I, Pierani A.

Cell Death Differ. 2016 Feb;23(2):323-32. doi: 10.1038/cdd.2015.100. Epub 2015 Jul 24.


Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance.

Ozmadenci D, Féraud O, Markossian S, Kress E, Ducarouge B, Gibert B, Ge J, Durand I, Gadot N, Plateroti M, Bennaceur-Griscelli A, Scoazec JY, Gil J, Deng H, Bernet A, Mehlen P, Lavial F.

Nat Commun. 2015 Jul 8;6:7398. doi: 10.1038/ncomms8398.


Secreted HHIP1 interacts with heparan sulfate and regulates Hedgehog ligand localization and function.

Holtz AM, Griffiths SC, Davis SJ, Bishop B, Siebold C, Allen BL.

J Cell Biol. 2015 Jun 8;209(5):739-57. doi: 10.1083/jcb.201411024.


Novel patched 1 mutations in patients with nevoid basal cell carcinoma syndrome--case report.

Škodrić-Trifunović V, Stjepanović M, Savić Ž, Ilić M, Kavečan I, Jovanović Privrodski J, Spasovski V, Stojiljković M, Pavlović S.

Croat Med J. 2015 Feb;56(1):63-7.


FoxA4 favours notochord formation by inhibiting contiguous mesodermal fates and restricts anterior neural development in Xenopus embryos.

Murgan S, Castro Colabianchi AM, Monti RJ, Boyadjián López LE, Aguirre CE, Stivala EG, Carrasco AE, López SL.

PLoS One. 2014 Oct 24;9(10):e110559. doi: 10.1371/journal.pone.0110559. eCollection 2014.


Whole-exome sequencing of muscle-invasive bladder cancer identifies recurrent mutations of UNC5C and prognostic importance of DNA repair gene mutations on survival.

Yap KL, Kiyotani K, Tamura K, Antic T, Jang M, Montoya M, Campanile A, Yew PY, Ganshert C, Fujioka T, Steinberg GD, O'Donnell PH, Nakamura Y.

Clin Cancer Res. 2014 Dec 15;20(24):6605-17. doi: 10.1158/1078-0432.CCR-14-0257. Epub 2014 Oct 14.


Co-ordinated brain and craniofacial development depend upon Patched1/XIAP regulation of cell survival.

Aoto K, Trainor PA.

Hum Mol Genet. 2015 Feb 1;24(3):698-713. doi: 10.1093/hmg/ddu489. Epub 2014 Oct 6.


Roles for Hedgehog signaling in adult organ homeostasis and repair.

Petrova R, Joyner AL.

Development. 2014 Sep;141(18):3445-57. doi: 10.1242/dev.083691. Review.


Patched-1 proapoptotic activity is downregulated by modification of K1413 by the E3 ubiquitin-protein ligase Itchy homolog.

Chen XL, Chinchilla P, Fombonne J, Ho L, Guix C, Keen JH, Mehlen P, Riobo NA.

Mol Cell Biol. 2014 Oct;34(20):3855-66. doi: 10.1128/MCB.00960-14. Epub 2014 Aug 4.


Sonic hedgehog signaling in the lung. From development to disease.

Kugler MC, Joyner AL, Loomis CA, Munger JS.

Am J Respir Cell Mol Biol. 2015 Jan;52(1):1-13. doi: 10.1165/rcmb.2014-0132TR. Review.


Boc modifies the spectrum of holoprosencephaly in the absence of Gas1 function.

Seppala M, Xavier GM, Fan CM, Cobourne MT.

Biol Open. 2014 Jul 25;3(8):728-40. doi: 10.1242/bio.20147989.


PTCH1 gene mutations in Keratocystic odontogenic tumors: a study of 43 Chinese patients and a systematic review.

Guo YY, Zhang JY, Li XF, Luo HY, Chen F, Li TJ.

PLoS One. 2013 Oct 21;8(10):e77305. doi: 10.1371/journal.pone.0077305. eCollection 2013. Review.


Transient activation of hedgehog pathway rescued irradiation-induced hyposalivation by preserving salivary stem/progenitor cells and parasympathetic innervation.

Hai B, Qin L, Yang Z, Zhao Q, Shangguan L, Ti X, Zhao Y, Kim S, Rangaraj D, Liu F.

Clin Cancer Res. 2014 Jan 1;20(1):140-50. doi: 10.1158/1078-0432.CCR-13-1434. Epub 2013 Oct 22.


FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function.

Shats I, Gatza ML, Liu B, Angus SP, You L, Nevins JR.

Cancer Res. 2013 Oct 1;73(19):6056-67. doi: 10.1158/0008-5472.CAN-13-0453. Epub 2013 Aug 21.

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