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Items: 1 to 20 of 29

1.

Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion.

Zhu Q, Yamakuchi M, Ture S, de la Luz Garcia-Hernandez M, Ko KA, Modjeski KL, LoMonaco MB, Johnson AD, O'Donnell CJ, Takai Y, Morrell CN, Lowenstein CJ.

J Clin Invest. 2014 Oct;124(10):4503-16. doi: 10.1172/JCI71245. Epub 2014 Sep 17.

2.

Platelet secretion and hemostasis require syntaxin-binding protein STXBP5.

Ye S, Huang Y, Joshi S, Zhang J, Yang F, Zhang G, Smyth SS, Li Z, Takai Y, Whiteheart SW.

J Clin Invest. 2014 Oct;124(10):4517-28. doi: 10.1172/JCI75572. Epub 2014 Sep 17.

3.

The N- and C-terminal domains of tomosyn play distinct roles in soluble N-ethylmaleimide-sensitive factor attachment protein receptor binding and fusion regulation.

Yu H, Rathore SS, Gulbranson DR, Shen J.

J Biol Chem. 2014 Sep 12;289(37):25571-80. doi: 10.1074/jbc.M114.591487. Epub 2014 Jul 25.

4.

Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion.

Bhatnagar S, Soni MS, Wrighton LS, Hebert AS, Zhou AS, Paul PK, Gregg T, Rabaglia ME, Keller MP, Coon JJ, Attie AD.

J Biol Chem. 2014 Sep 5;289(36):25276-86. doi: 10.1074/jbc.M114.575985. Epub 2014 Jul 7.

5.

Differential interaction of tomosyn with syntaxin and SNAP25 depends on domains in the WD40 β-propeller core and determines its inhibitory activity.

Bielopolski N, Lam AD, Bar-On D, Sauer M, Stuenkel EL, Ashery U.

J Biol Chem. 2014 Jun 13;289(24):17087-99. doi: 10.1074/jbc.M113.515296. Epub 2014 Apr 29.

6.

Performance related factors are the main determinants of the von Willebrand factor response to exhaustive physical exercise.

van Loon JE, Sonneveld MA, Praet SF, de Maat MP, Leebeek FW.

PLoS One. 2014 Mar 13;9(3):e91687. doi: 10.1371/journal.pone.0091687. eCollection 2014.

7.

MicroRNA-494, upregulated by tumor necrosis factor-α, desensitizes insulin effect in C2C12 muscle cells.

Lee H, Jee Y, Hong K, Hwang GS, Chun KH.

PLoS One. 2013 Dec 11;8(12):e83471. doi: 10.1371/journal.pone.0083471. eCollection 2013.

8.

Effect of genetic variation in STXBP5 and STX2 on von Willebrand factor and bleeding phenotype in type 1 von Willebrand disease patients.

van Loon JE, Sanders YV, de Wee EM, Kruip MJ, de Maat MP, Leebeek FW.

PLoS One. 2012;7(7):e40624. doi: 10.1371/journal.pone.0040624. Epub 2012 Jul 6.

9.

GLUT4 exocytosis.

Stöckli J, Fazakerley DJ, James DE.

J Cell Sci. 2011 Dec 15;124(Pt 24):4147-59. doi: 10.1242/jcs.097063. Review.

10.

Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion.

Bhatnagar S, Oler AT, Rabaglia ME, Stapleton DS, Schueler KL, Truchan NA, Worzella SL, Stoehr JP, Clee SM, Yandell BS, Keller MP, Thurmond DC, Attie AD.

PLoS Genet. 2011 Oct;7(10):e1002323. doi: 10.1371/journal.pgen.1002323. Epub 2011 Oct 6.

11.

Breaking Caenorhabditis elegans the easy way using the Balch homogenizer: an old tool for a new application.

Bhaskaran S, Butler JA, Becerra S, Fassio V, Girotti M, Rea SL.

Anal Biochem. 2011 Jun 15;413(2):123-32. doi: 10.1016/j.ab.2011.02.029. Epub 2011 Feb 24.

12.

Structural and functional analysis of tomosyn identifies domains important in exocytotic regulation.

Williams AL, Bielopolski N, Meroz D, Lam AD, Passmore DR, Ben-Tal N, Ernst SA, Ashery U, Stuenkel EL.

J Biol Chem. 2011 Apr 22;286(16):14542-53. doi: 10.1074/jbc.M110.215624. Epub 2011 Feb 17.

13.

Functional architecture of Weibel-Palade bodies.

Valentijn KM, Sadler JE, Valentijn JA, Voorberg J, Eikenboom J.

Blood. 2011 May 12;117(19):5033-43. doi: 10.1182/blood-2010-09-267492. Epub 2011 Jan 25. Review.

14.

Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4.

Jewell JL, Oh E, Thurmond DC.

Am J Physiol Regul Integr Comp Physiol. 2010 Mar;298(3):R517-31. doi: 10.1152/ajpregu.00597.2009. Epub 2010 Jan 6. Review.

15.

Syntaxin specificity of aquaporins in the inner medullary collecting duct.

Mistry AC, Mallick R, Klein JD, Weimbs T, Sands JM, Fröhlich O.

Am J Physiol Renal Physiol. 2009 Aug;297(2):F292-300. doi: 10.1152/ajprenal.00196.2009. Epub 2009 Jun 10.

16.

Friends and foes in synaptic transmission: the role of tomosyn in vesicle priming.

Ashery U, Bielopolski N, Barak B, Yizhar O.

Trends Neurosci. 2009 May;32(5):275-82. doi: 10.1016/j.tins.2009.01.004. Epub 2009 Mar 21. Review.

17.

DOC2B: a novel syntaxin-4 binding protein mediating insulin-regulated GLUT4 vesicle fusion in adipocytes.

Fukuda N, Emoto M, Nakamori Y, Taguchi A, Miyamoto S, Uraki S, Oka Y, Tanizawa Y.

Diabetes. 2009 Feb;58(2):377-84. doi: 10.2337/db08-0303. Epub 2008 Nov 25.

18.

Skeletal muscle munc18c and syntaxin 4 in human obesity.

Bergman BC, Cornier MA, Horton TJ, Bessesen DH, Eckel RH.

Nutr Metab (Lond). 2008 Jul 24;5:21. doi: 10.1186/1743-7075-5-21.

19.

Modulating vesicle priming reveals that vesicle immobilization is necessary but not sufficient for fusion-competence.

Yizhar O, Ashery U.

PLoS One. 2008 Jul 16;3(7):e2694. doi: 10.1371/journal.pone.0002694.

20.

The tyrosine phosphorylation of Munc18c induces a switch in binding specificity from syntaxin 4 to Doc2beta.

Jewell JL, Oh E, Bennett SM, Meroueh SO, Thurmond DC.

J Biol Chem. 2008 Aug 1;283(31):21734-46. doi: 10.1074/jbc.M710445200. Epub 2008 Jun 9.

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