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Items: 19


GBT1118, a potent allosteric modifier of hemoglobin O2 affinity, increases tolerance to severe hypoxia in mice.

Dufu K, Yalcin O, Ao-Ieong ESY, Hutchaleelala A, Xu Q, Li Z, Vlahakis N, Oksenberg D, Lehrer-Graiwer J, Cabrales P.

Am J Physiol Heart Circ Physiol. 2017 Aug 1;313(2):H381-H391. doi: 10.1152/ajpheart.00772.2016. Epub 2017 May 19.


Multiparametric [18F]Fluorodeoxyglucose/ [18F]Fluoromisonidazole Positron Emission Tomography/ Magnetic Resonance Imaging of Locally Advanced Cervical Cancer for the Non-Invasive Detection of Tumor Heterogeneity: A Pilot Study.

Pinker K, Andrzejewski P, Baltzer P, Polanec SH, Sturdza A, Georg D, Helbich TH, Karanikas G, Grimm C, Polterauer S, Poetter R, Wadsak W, Mitterhauser M, Georg P.

PLoS One. 2016 May 11;11(5):e0155333. doi: 10.1371/journal.pone.0155333. eCollection 2016.


In Vivo Chemiluminescent Imaging Agents for Nitroreductase and Tissue Oxygenation.

Cao J, Campbell J, Liu L, Mason RP, Lippert AR.

Anal Chem. 2016 May 3;88(9):4995-5002. doi: 10.1021/acs.analchem.6b01096. Epub 2016 Apr 15.


Analysis of the intra- and intertumoral heterogeneity of hypoxia in pancreatic cancer patients receiving the nitroimidazole tracer pimonidazole.

Dhani NC, Serra S, Pintilie M, Schwock J, Xu J, Gallinger S, Hill RP, Hedley DW.

Br J Cancer. 2015 Sep 15;113(6):864-71. doi: 10.1038/bjc.2015.284. Epub 2015 Sep 1.


Physiologic hypoxia and oxygen homeostasis in the healthy intestine. A Review in the Theme: Cellular Responses to Hypoxia.

Zheng L, Kelly CJ, Colgan SP.

Am J Physiol Cell Physiol. 2015 Sep 15;309(6):C350-60. doi: 10.1152/ajpcell.00191.2015. Epub 2015 Jul 15. Review.


Optimizing hypoxia detection and treatment strategies.

Koch CJ, Evans SM.

Semin Nucl Med. 2015 Mar;45(2):163-76. doi: 10.1053/j.semnuclmed.2014.10.004. Review.


Molecular probes for imaging of hypoxia in the retina.

Evans SM, Kim K, Moore CE, Uddin MI, Capozzi ME, Craft JR, Sulikowski GA, Jayagopal A.

Bioconjug Chem. 2014 Nov 19;25(11):2030-7. doi: 10.1021/bc500400z. Epub 2014 Oct 9.


Cherenkov excited phosphorescence-based pO2 estimation during multi-beam radiation therapy: phantom and simulation studies.

Holt RW, Zhang R, Esipova TV, Vinogradov SA, Glaser AK, Gladstone DJ, Pogue BW.

Phys Med Biol. 2014 Sep 21;59(18):5317-5328. doi: 10.1088/0031-9155/59/18/5317. Epub 2014 Aug 22.


Characterization of the Tumor-Microenvironment in Patient-Derived Cervix Xenografts (OCICx).

Chaudary N, Pintilie M, Schwock J, Dhani N, Clarke B, Milosevic M, Fyles A, Hill RP.

Cancers (Basel). 2012 Aug 29;4(3):821-45. doi: 10.3390/cancers4030821.


Oxygen tomography by Čerenkov-excited phosphorescence during external beam irradiation.

Zhang R, Davis SC, Demers JL, Glaser AK, Gladstone DJ, Esipova TV, Vinogradov SA, Pogue BW.

J Biomed Opt. 2013 May;18(5):50503. doi: 10.1117/1.JBO.18.5.050503.


Theranostic oxygen delivery using ultrasound and microbubbles.

Kwan JJ, Kaya M, Borden MA, Dayton PA.

Theranostics. 2012;2(12):1174-84. doi: 10.7150/thno.4410. Epub 2012 Dec 23.


Čerenkov radiation emission and excited luminescence (CREL) sensitivity during external beam radiation therapy: Monte Carlo and tissue oxygenation phantom studies.

Zhang R, Glaser A, Esipova TV, Kanick SC, Davis SC, Vinogradov S, Gladstone D, Pogue BW.

Biomed Opt Express. 2012 Oct 1;3(10):2381-94. doi: 10.1364/BOE.3.002381. Epub 2012 Sep 5.


Modeling the spatial distribution of chronic tumor hypoxia: implications for experimental and clinical studies.

Powathil G, Kohandel M, Milosevic M, Sivaloganathan S.

Comput Math Methods Med. 2012;2012:410602. doi: 10.1155/2012/410602. Epub 2012 Jan 29.


A robotic system for 18F-FMISO PET-guided intratumoral pO2 measurements.

Chang J, Wen B, Kazanzides P, Zanzonico P, Finn RD, Fichtinger G, Ling CC.

Med Phys. 2009 Nov;36(11):5301-9.


Imaging and analytical methods as applied to the evaluation of vasculature and hypoxia in human brain tumors.

Evans SM, Jenkins KW, Jenkins WT, Dilling T, Judy KD, Schrlau A, Judkins A, Hahn SM, Koch CJ.

Radiat Res. 2008 Dec;170(6):677-90. doi: 10.1667/RR1207.1.


Expression of carbonic anhydrase 9, a potential intrinsic marker of hypoxia, is associated with poor prognosis in oesophageal squamous cell carcinoma.

Tanaka N, Kato H, Inose T, Kimura H, Faried A, Sohda M, Nakajima M, Fukai Y, Miyazaki T, Masuda N, Fukuchi M, Kuwano H.

Br J Cancer. 2008 Nov 4;99(9):1468-75. doi: 10.1038/sj.bjc.6604719. Epub 2008 Oct 7.


Hypoxia-associated markers in gastric carcinogenesis and HIF-2alpha in gastric and gastro-oesophageal cancer prognosis.

Griffiths EA, Pritchard SA, McGrath SM, Valentine HR, Price PM, Welch IM, West CM.

Br J Cancer. 2008 Mar 11;98(5):965-73. doi: 10.1038/sj.bjc.6604210. Epub 2008 Feb 19.


Involvement of hypoxia-inducible transcription factors in polycystic kidney disease.

Bernhardt WM, Wiesener MS, Weidemann A, Schmitt R, Weichert W, Lechler P, Campean V, Ong AC, Willam C, Gretz N, Eckardt KU.

Am J Pathol. 2007 Mar;170(3):830-42.

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