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Items: 7

1.

Structure-based discovery of selective positive allosteric modulators of antagonists for the M2 muscarinic acetylcholine receptor.

Korczynska M, Clark MJ, Valant C, Xu J, Moo EV, Albold S, Weiss DR, Torosyan H, Huang W, Kruse AC, Lyda BR, May LT, Baltos JA, Sexton PM, Kobilka BK, Christopoulos A, Shoichet BK, Sunahara RK.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2419-E2428. doi: 10.1073/pnas.1718037115. Epub 2018 Feb 16.

2.

Imaging of the muscarinic acetylcholine neuroreceptor in rats with the M2 selective agonist [18F]FP-TZTP.

Ravasi L, Tokugawa J, Nakayama T, Seidel J, Sokoloff L, Eckelman WC, Kiesewetter DO.

Nucl Med Biol. 2012 Jan;39(1):45-55. doi: 10.1016/j.nucmedbio.2011.06.003. Epub 2011 Aug 9.

3.

Hippocampal M1 receptor function associated with spatial learning and memory in aged female rhesus macaques.

Haley GE, Kroenke C, Schwartz D, Kohama SG, Urbanski HF, Raber J.

Age (Dordr). 2011 Sep;33(3):309-20. doi: 10.1007/s11357-010-9184-2. Epub 2010 Oct 2.

4.

Applications of LC-MS in PET radioligand development and metabolic elucidation.

Ma Y, Kiesewetter DO, Lang L, Gu D, Chen X.

Curr Drug Metab. 2010 Jul;11(6):483-93. Review.

5.

Genetic variation in cholinergic muscarinic-2 receptor gene modulates M2 receptor binding in vivo and accounts for reduced binding in bipolar disorder.

Cannon DM, Klaver JK, Gandhi SK, Solorio G, Peck SA, Erickson K, Akula N, Savitz J, Eckelman WC, Furey ML, Sahakian BJ, McMahon FJ, Drevets WC.

Mol Psychiatry. 2011 Apr;16(4):407-18. doi: 10.1038/mp.2010.24. Epub 2010 Mar 30.

6.

Decreased muscarinic receptor binding in the frontal cortex of bipolar disorder and major depressive disorder subjects.

Gibbons AS, Scarr E, McLean C, Sundram S, Dean B.

J Affect Disord. 2009 Aug;116(3):184-91. doi: 10.1016/j.jad.2008.11.015. Epub 2008 Dec 21.

7.

Comparison of the pharmacokinetics of different analogs of 11C-labeled TZTP for imaging muscarinic M2 receptors with PET.

Reid AE, Ding YS, Eckelman WC, Logan J, Alexoff D, Shea C, Xu Y, Fowler JS.

Nucl Med Biol. 2008 Apr;35(3):287-98. doi: 10.1016/j.nucmedbio.2008.01.001.

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