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Items: 1 to 20 of 41

1.

SIK2 attenuates proliferation and survival of breast cancer cells with simultaneous perturbation of MAPK and PI3K/Akt pathways.

Zohrap N, Saatci Ö, Ozes B, Coban I, Atay HM, Battaloglu E, Şahin Ö, Bugra K.

Oncotarget. 2018 Apr 24;9(31):21876-21892. doi: 10.18632/oncotarget.25082. eCollection 2018 Apr 24.

2.

LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia.

Tarumoto Y, Lu B, Somerville TDD, Huang YH, Milazzo JP, Wu XS, Klingbeil O, El Demerdash O, Shi J, Vakoc CR.

Mol Cell. 2018 Mar 15;69(6):1017-1027.e6. doi: 10.1016/j.molcel.2018.02.011. Epub 2018 Mar 8.

PMID:
29526696
3.

A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin.

Mujahid N, Liang Y, Murakami R, Choi HG, Dobry AS, Wang J, Suita Y, Weng QY, Allouche J, Kemeny LV, Hermann AL, Roider EM, Gray NS, Fisher DE.

Cell Rep. 2017 Jun 13;19(11):2177-2184. doi: 10.1016/j.celrep.2017.05.042.

4.

Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages.

Darling NJ, Toth R, Arthur JS, Clark K.

Biochem J. 2017 Feb 15;474(4):521-537. doi: 10.1042/BCJ20160646. Epub 2016 Dec 5.

5.

Activation of salt-inducible kinase 2 promotes the viability of peritoneal mesothelial cells exposed to stress of peritoneal dialysis.

Wang HH, Lin CY, Su SH, Chuang CT, Chang YL, Lee TY, Lee SC, Chang CJ.

Cell Death Dis. 2016 Jul 21;7:e2298. doi: 10.1038/cddis.2016.79.

6.

Skeletal muscle salt inducible kinase 1 promotes insulin resistance in obesity.

Nixon M, Stewart-Fitzgibbon R, Fu J, Akhmedov D, Rajendran K, Mendoza-Rodriguez MG, Rivera-Molina YA, Gibson M, Berglund ED, Justice NJ, Berdeaux R.

Mol Metab. 2015 Nov 6;5(1):34-46. doi: 10.1016/j.molmet.2015.10.004. eCollection 2016 Jan.

7.

Salt-inducible Kinase 3 Signaling Is Important for the Gluconeogenic Programs in Mouse Hepatocytes.

Itoh Y, Sanosaka M, Fuchino H, Yahara Y, Kumagai A, Takemoto D, Kagawa M, Doi J, Ohta M, Tsumaki N, Kawahara N, Takemori H.

J Biol Chem. 2015 Jul 17;290(29):17879-93. doi: 10.1074/jbc.M115.640821. Epub 2015 Jun 5.

8.

Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo.

Wu Y, Song P, Zhang W, Liu J, Dai X, Liu Z, Lu Q, Ouyang C, Xie Z, Zhao Z, Zhuo X, Viollet B, Foretz M, Wu J, Yuan Z, Zou MH.

Nat Med. 2015 Apr;21(4):373-82. doi: 10.1038/nm.3826. Epub 2015 Mar 23.

9.

Salt-inducible kinase 2 regulates mitotic progression and transcription in prostate cancer.

Bon H, Wadhwa K, Schreiner A, Osborne M, Carroll T, Ramos-Montoya A, Ross-Adams H, Visser M, Hoffmann R, Ahmed AA, Neal DE, Mills IG.

Mol Cancer Res. 2015 Apr;13(4):620-635. doi: 10.1158/1541-7786.MCR-13-0182-T. Epub 2014 Dec 29.

10.

SIK2 regulates CRTCs, HDAC4 and glucose uptake in adipocytes.

Henriksson E, Säll J, Gormand A, Wasserstrom S, Morrice NA, Fritzen AM, Foretz M, Campbell DG, Sakamoto K, Ekelund M, Degerman E, Stenkula KG, Göransson O.

J Cell Sci. 2015 Feb 1;128(3):472-86.

11.

The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.

Patel K, Foretz M, Marion A, Campbell DG, Gourlay R, Boudaba N, Tournier E, Titchenell P, Peggie M, Deak M, Wan M, Kaestner KH, Göransson O, Viollet B, Gray NS, Birnbaum MJ, Sutherland C, Sakamoto K.

Nat Commun. 2014 Aug 4;5:4535. doi: 10.1038/ncomms5535.

13.

Lack of salt-inducible kinase 2 (SIK2) prevents the development of cardiac hypertrophy in response to chronic high-salt intake.

Popov S, Takemori H, Tokudome T, Mao Y, Otani K, Mochizuki N, Pires N, Pinho MJ, Franco-Cereceda A, Torielli L, Ferrandi M, Hamsten A, Soares-da-Silva P, Eriksson P, Bertorello AM, Brion L.

PLoS One. 2014 Apr 21;9(4):e95771. doi: 10.1371/journal.pone.0095771. eCollection 2014.

14.

Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation.

Hançer NJ, Qiu W, Cherella C, Li Y, Copps KD, White MF.

J Biol Chem. 2014 May 2;289(18):12467-84. doi: 10.1074/jbc.M114.554162. Epub 2014 Mar 20.

15.

Interaction between salt-inducible kinase 2 (SIK2) and p97/valosin-containing protein (VCP) regulates endoplasmic reticulum (ER)-associated protein degradation in mammalian cells.

Yang FC, Lin YH, Chen WH, Huang JY, Chang HY, Su SH, Wang HT, Chiang CY, Hsu PH, Tsai MD, Tan BC, Lee SC.

J Biol Chem. 2013 Nov 22;288(47):33861-72. doi: 10.1074/jbc.M113.492199. Epub 2013 Oct 15.

16.

AMPK and Exercise: Glucose Uptake and Insulin Sensitivity.

O'Neill HM.

Diabetes Metab J. 2013 Feb;37(1):1-21. doi: 10.4093/dmj.2013.37.1.1. Epub 2013 Feb 15. Erratum in: Diabetes Metab J. 2013 Apr;37(2):155.

17.

The tumor suppressor kinase LKB1 activates the downstream kinases SIK2 and SIK3 to stimulate nuclear export of class IIa histone deacetylases.

Walkinshaw DR, Weist R, Kim GW, You L, Xiao L, Nie J, Li CS, Zhao S, Xu M, Yang XJ.

J Biol Chem. 2013 Mar 29;288(13):9345-62. doi: 10.1074/jbc.M113.456996. Epub 2013 Feb 7.

18.

Role of salt-inducible kinase 1 in the activation of MEF2-dependent transcription by BDNF.

Finsterwald C, Carrard A, Martin JL.

PLoS One. 2013;8(1):e54545. doi: 10.1371/journal.pone.0054545. Epub 2013 Jan 22.

19.

Reversible acetylation regulates salt-inducible kinase (SIK2) and its function in autophagy.

Yang FC, Tan BC, Chen WH, Lin YH, Huang JY, Chang HY, Sun HY, Hsu PH, Liou GG, Shen J, Chang CJ, Han CC, Tsai MD, Lee SC.

J Biol Chem. 2013 Mar 1;288(9):6227-37. doi: 10.1074/jbc.M112.431239. Epub 2013 Jan 15.

20.

Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila.

Wehr MC, Holder MV, Gailite I, Saunders RE, Maile TM, Ciirdaeva E, Instrell R, Jiang M, Howell M, Rossner MJ, Tapon N.

Nat Cell Biol. 2013 Jan;15(1):61-71.

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