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Items: 1 to 20 of 37


Coordination of the recruitment of the FANCD2 and PALB2 Fanconi anemia proteins by an ubiquitin signaling network.

Bick G, Zhang F, Meetei AR, Andreassen PR.

Chromosoma. 2016 Jun 8. [Epub ahead of print]


ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination.

Khair L, Guikema JE, Linehan EK, Ucher AJ, Leus NG, Ogilvie C, Lou Z, Schrader CE, Stavnezer J.

J Immunol. 2014 May 15;192(10):4887-96. doi: 10.4049/jimmunol.1303481. Epub 2014 Apr 11.


Quantitation of DNA double-strand break resection intermediates in human cells.

Zhou Y, Caron P, Legube G, Paull TT.

Nucleic Acids Res. 2014 Feb;42(3):e19. doi: 10.1093/nar/gkt1309. Epub 2013 Dec 19.


Acetylation of lysine 382 and phosphorylation of serine 392 in p53 modulate the interaction between p53 and MDC1 in vitro.

Shahar OD, Gabizon R, Feine O, Alhadeff R, Ganoth A, Argaman L, Shimshoni E, Friedler A, Goldberg M.

PLoS One. 2013 Oct 23;8(10):e78472. doi: 10.1371/journal.pone.0078472. eCollection 2013 Oct 23.


Differing clinical impact of BRCA1 and BRCA2 mutations in serous ovarian cancer.

Liu G, Yang D, Sun Y, Shmulevich I, Xue F, Sood AK, Zhang W.

Pharmacogenomics. 2012 Oct;13(13):1523-35. doi: 10.2217/pgs.12.137. Review.


MDC1 and RNF8 function in a pathway that directs BRCA1-dependent localization of PALB2 required for homologous recombination.

Zhang F, Bick G, Park JY, Andreassen PR.

J Cell Sci. 2012 Dec 15;125(Pt 24):6049-57. doi: 10.1242/jcs.111872. Epub 2012 Oct 4.


Sumoylation of MDC1 is important for proper DNA damage response.

Luo K, Zhang H, Wang L, Yuan J, Lou Z.

EMBO J. 2012 Jun 29;31(13):3008-19. doi: 10.1038/emboj.2012.158. Epub 2012 May 25.


A novel sLRP6E1E2 inhibits canonical Wnt signaling, epithelial-to-mesenchymal transition, and induces mitochondria-dependent apoptosis in lung cancer.

Lee JS, Hur MW, Lee SK, Choi WI, Kwon YG, Yun CO.

PLoS One. 2012;7(5):e36520. doi: 10.1371/journal.pone.0036520. Epub 2012 May 14.


Oligomerization of MDC1 protein is important for proper DNA damage response.

Luo K, Yuan J, Lou Z.

J Biol Chem. 2011 Aug 12;286(32):28192-9. doi: 10.1074/jbc.M111.258087. Epub 2011 Jun 24.


Chalcone-imidazolone conjugates induce apoptosis through DNA damage pathway by affecting telomeres.

Ramaiah MJ, Pushpavalli S, Krishna GR, Sarma P, Mukhopadhyay D, Kamal A, Bhadra U, Bhadra MP.

Cancer Cell Int. 2011 Apr 25;11:11. doi: 10.1186/1475-2867-11-11.


HP1alpha recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair.

Baldeyron C, Soria G, Roche D, Cook AJ, Almouzni G.

J Cell Biol. 2011 Apr 4;193(1):81-95. doi: 10.1083/jcb.201101030.


Nek1 kinase functions in DNA damage response and checkpoint control through a pathway independent of ATM and ATR.

Chen Y, Chen CF, Riley DJ, Chen PL.

Cell Cycle. 2011 Feb 15;10(4):655-63. Epub 2011 Feb 15.


Histone tyrosine phosphorylation comes of age.

Singh RK, Gunjan A.

Epigenetics. 2011 Feb;6(2):153-60. Epub 2011 Feb 1. Review. Erratum in: Epigenetics. 2011 Dec 1;6(12):1513.


A divalent FHA/BRCT-binding mechanism couples the MRE11-RAD50-NBS1 complex to damaged chromatin.

Hari FJ, Spycher C, Jungmichel S, Pavic L, Stucki M.

EMBO Rep. 2010 May;11(5):387-92. doi: 10.1038/embor.2010.30. Epub 2010 Mar 12.


BRCA1 and its toolbox for the maintenance of genome integrity.

Huen MS, Sy SM, Chen J.

Nat Rev Mol Cell Biol. 2010 Feb;11(2):138-48. doi: 10.1038/nrm2831. Epub 2009 Dec 23. Review.


CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response.

Becherel OJ, Jakob B, Cherry AL, Gueven N, Fusser M, Kijas AW, Peng C, Katyal S, McKinnon PJ, Chen J, Epe B, Smerdon SJ, Taucher-Scholz G, Lavin MF.

Nucleic Acids Res. 2010 Mar;38(5):1489-503. doi: 10.1093/nar/gkp1149. Epub 2009 Dec 14.


MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX.

Yuan J, Chen J.

J Biol Chem. 2010 Jan 8;285(2):1097-104. doi: 10.1074/jbc.M109.078436. Epub 2009 Nov 12.


Mechanisms of double-strand break repair in somatic mammalian cells.

Hartlerode AJ, Scully R.

Biochem J. 2009 Sep 25;423(2):157-68. doi: 10.1042/BJ20090942. Review. Erratum in: Biochem J. 2010 Mar 15;426(3):389.


N terminus of CtIP is critical for homologous recombination-mediated double-strand break repair.

Yuan J, Chen J.

J Biol Chem. 2009 Nov 13;284(46):31746-52. doi: 10.1074/jbc.M109.023424. Epub 2009 Sep 16.


SOSS complexes participate in the maintenance of genomic stability.

Huang J, Gong Z, Ghosal G, Chen J.

Mol Cell. 2009 Aug 14;35(3):384-93. doi: 10.1016/j.molcel.2009.06.011.

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