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Items: 1 to 20 of 249


The loss of ATP2C1 impairs the DNA damage response and induces altered skin homeostasis: Consequences for epidermal biology in Hailey-Hailey disease.

Cialfi S, Le Pera L, De Blasio C, Mariano G, Palermo R, Zonfrilli A, Uccelletti D, Palleschi C, Biolcati G, Barbieri L, Screpanti I, Talora C.

Sci Rep. 2016 Aug 16;6:31567. doi: 10.1038/srep31567.


LGN plays distinct roles in oral epithelial stratification, filiform papilla morphogenesis and hair follicle development.

Byrd KM, Lough KJ, Patel JH, Descovich CP, Curtis TA, Williams SE.

Development. 2016 Aug 1;143(15):2803-17. doi: 10.1242/dev.136010. Epub 2016 Jun 17.


Does Notch play a tumor suppressor role across diverse squamous cell carcinomas?

Zhang M, Biswas S, Qin X, Gong W, Deng W, Yu H.

Cancer Med. 2016 Aug;5(8):2048-60. doi: 10.1002/cam4.731. Epub 2016 May 26. Review.


Notch Signaling in Neuroendocrine Tumors.

Crabtree JS, Singleton CS, Miele L.

Front Oncol. 2016 Apr 14;6:94. doi: 10.3389/fonc.2016.00094. eCollection 2016. Review.


Changing the paradigm: the potential for targeted therapy in laryngeal squamous cell carcinoma.

Ludwig ML, Birkeland AC, Hoesli R, Swiecicki P, Spector ME, Brenner JC.

Cancer Biol Med. 2016 Mar;13(1):87-100. doi: 10.28092/j.issn.2095-3941.2016.0010.


In vivo Wnt pathway inhibition of human squamous cell carcinoma growth and metastasis in the chick chorioallantoic model.

Rudy SF, Brenner JC, Harris JL, Liu J, Che J, Scott MV, Owen JH, Komarck CM, Graham MP, Bellile EL, Bradford CR, Prince ME, Carey TE.

J Otolaryngol Head Neck Surg. 2016 Apr 26;45:26. doi: 10.1186/s40463-016-0140-8.


Deletion of the γ-secretase subunits Aph1B/C impairs memory and worsens the deficits of knock-in mice modeling the Alzheimer-like familial Danish dementia.

Biundo F, Ishiwari K, Del Prete D, D'Adamio L.

Oncotarget. 2016 Mar 15;7(11):11923-44. doi: 10.18632/oncotarget.7389.


Interaction of Wnt5a with Notch1 is Critical for the Pathogenesis of Psoriasis.

Kim JE, Bang SH, Choi JH, Kim CD, Won CH, Lee MW, Chang SE.

Ann Dermatol. 2016 Feb;28(1):45-54. doi: 10.5021/ad.2016.28.1.45. Epub 2016 Jan 28.


Targeting the Notch signaling pathway in cancer therapeutics.

Guo H, Lu Y, Wang J, Liu X, Keller ET, Liu Q, Zhou Q, Zhang J.

Thorac Cancer. 2014 Nov;5(6):473-86. doi: 10.1111/1759-7714.12143. Epub 2014 Oct 23. Review.


Concise Review: Paracrine Role of Stem Cells in Pituitary Tumors: A Focus on Adamantinomatous Craniopharyngioma.

Martinez-Barbera JP, Andoniadou CL.

Stem Cells. 2016 Feb;34(2):268-76. doi: 10.1002/stem.2267. Epub 2016 Jan 13.


Targeting Notch to overcome radiation resistance.

Yahyanejad S, Theys J, Vooijs M.

Oncotarget. 2016 Feb 16;7(7):7610-28. doi: 10.18632/oncotarget.6714. Review.


The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies.

Yang K, Wang X, Zhang H, Wang Z, Nan G, Li Y, Zhang F, Mohammed MK, Haydon RC, Luu HH, Bi Y, He TC.

Lab Invest. 2016 Feb;96(2):116-36. doi: 10.1038/labinvest.2015.144. Epub 2015 Nov 30.


Mutually exclusive mutations in NOTCH1 and PIK3CA associated with clinical prognosis and chemotherapy responses of esophageal squamous cell carcinoma in China.

Song B, Cui H, Li Y, Cheng C, Yang B, Wang F, Kong P, Li H, Zhang L, Jia Z, Bi Y, Wang J, Zhou Y, Liu J, Wang J, Zhao Z, Zhang Y, Hu X, Shi R, Yang J, Liu H, Yan T, Li Y, Xu E, Qian Y, Xi Y, Guo S, Chen Y, Wang J, Li G, Liang J, Jia J, Chen X, Guo J, Wang T, Zhang Y, Li Q, Wang C, Cheng X, Zhan Q, Cui Y.

Oncotarget. 2016 Jan 19;7(3):3599-613. doi: 10.18632/oncotarget.6120.


Papillomavirus E6 Oncoproteins Take Common Structural Approaches to Solve Different Biological Problems.

Vande Pol S.

PLoS Pathog. 2015 Oct 15;11(10):e1005138. doi: 10.1371/journal.ppat.1005138. eCollection 2015 Oct. Review. No abstract available.


Vav1: A Dr. Jekyll and Mr. Hyde protein--good for the hematopoietic system, bad for cancer.

Katzav S.

Oncotarget. 2015 Oct 6;6(30):28731-42. doi: 10.18632/oncotarget.5086. Review.


Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis.

Zhong R, Bao R, Faber PW, Bindokas VP, Bechill J, Lingen MW, Spiotto MT.

Cancer Res. 2015 Sep 15;75(18):3958-69. doi: 10.1158/0008-5472.CAN-15-0199. Epub 2015 Aug 20.


Targeting Wnt signaling in colorectal cancer. A Review in the Theme: Cell Signaling: Proteins, Pathways and Mechanisms.

Novellasdemunt L, Antas P, Li VS.

Am J Physiol Cell Physiol. 2015 Oct 15;309(8):C511-21. doi: 10.1152/ajpcell.00117.2015. Epub 2015 Aug 19. Review.


Pro-Inflammatory Cytokine IL-1β Up-Regulates CXC Chemokine Receptor 4 via Notch and ERK Signaling Pathways in Tongue Squamous Cell Carcinoma.

Sun Y, Zhu D, Wang G, Wang D, Zhou H, Liu X, Jiang M, Liao L, Zhou Z, Hu J.

PLoS One. 2015 Jul 15;10(7):e0132677. doi: 10.1371/journal.pone.0132677. eCollection 2015.


Overexpression of Notch1 is associated with the progression of cervical cancer.

Sun Y, Zhang R, Zhou S, Ji Y.

Oncol Lett. 2015 Jun;9(6):2750-2756. Epub 2015 Apr 23.


The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis.

Liu Z, Brunskill E, Varnum-Finney B, Zhang C, Zhang A, Jay PY, Bernstein I, Morimoto M, Kopan R.

Development. 2015 Jul 15;142(14):2452-63. doi: 10.1242/dev.125492. Epub 2015 Jun 10.

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