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Undiagnosed diabetes and impaired fasting glucose in HFE C282Y homozygotes and HFE wild-type controls in the HEIRS Study.

Barton JC, Barton JC, Adams PC, Acton RT.

BMJ Open Diabetes Res Care. 2016 Dec 26;4(1):e000278. doi: 10.1136/bmjdrc-2016-000278. eCollection 2016.


Risk Factors for Insulin Resistance, Metabolic Syndrome, and Diabetes in 248 HFE C282Y Homozygotes Identified by Population Screening in the HEIRS Study.

Barton JC, Barton JC, Adams PC, Acton RT.

Metab Syndr Relat Disord. 2016 Mar;14(2):94-101. doi: 10.1089/met.2015.0123. Epub 2016 Jan 15.


Serum ferritin, insulin resistance, and metabolic syndrome: clinical and laboratory associations in 769 non-hispanic whites without diabetes mellitus in the HEIRS study.

Acton RT, Barton JC, Barton JC.

Metab Syndr Relat Disord. 2015 Mar;13(2):57-63. doi: 10.1089/met.2014.0106. Epub 2014 Nov 25.


Elevated transferrin saturation, health-related quality of life and telomere length.

Mainous AG 3rd, Wright RU, Hulihan MM, Twal WO, McLaren CE, Diaz VA, McLaren GD, Argraves WS, Grant AM.

Biometals. 2014 Feb;27(1):135-41. doi: 10.1007/s10534-013-9693-4. Epub 2013 Dec 15.


HFE mutations in Caucasian participants of the Hemochromatosis and Iron Overload Screening study with serum ferritin level <1000 µg/L.

Adams PC, McLaren CE, Speechley M, McLaren GD, Barton JC, Eckfeldt JH.

Can J Gastroenterol. 2013 Jul;27(7):390-2.


Telomere length and elevated iron: the influence of phenotype and HFE genotype.

Mainous AG 3rd, Wright RU, Hulihan MM, Twal WO, McLaren CE, Diaz VA, McLaren GD, Argraves WS, Grant AM.

Am J Hematol. 2013 Jun;88(6):492-6. doi: 10.1002/ajh.23438. Epub 2013 May 13.


Association between celiac disease and iron deficiency in Caucasians, but not non-Caucasians.

Murray JA, McLachlan S, Adams PC, Eckfeldt JH, Garner CP, Vulpe CD, Gordeuk VR, Brantner T, Leiendecker-Foster C, Killeen AA, Acton RT, Barcellos LF, Nickerson DA, Beckman KB, McLaren GD, McLaren CE.

Clin Gastroenterol Hepatol. 2013 Jul;11(7):808-14. doi: 10.1016/j.cgh.2013.02.009. Epub 2013 Feb 13.


HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis.

White C, Yuan X, Schmidt PJ, Bresciani E, Samuel TK, Campagna D, Hall C, Bishop K, Calicchio ML, Lapierre A, Ward DM, Liu P, Fleming MD, Hamza I.

Cell Metab. 2013 Feb 5;17(2):261-70. doi: 10.1016/j.cmet.2013.01.005.


Hyperferritinemia and hyperuricemia may be associated with liver function abnormality in obese adolescents.

Chen SC, Huang YF, Wang JD.

PLoS One. 2012;7(10):e48645. doi: 10.1371/journal.pone.0048645. Epub 2012 Oct 31. Erratum in: PLoS One. 2017 Mar 7;12 (3):e0173849.


Associations between single nucleotide polymorphisms in iron-related genes and iron status in multiethnic populations.

McLaren CE, McLachlan S, Garner CP, Vulpe CD, Gordeuk VR, Eckfeldt JH, Adams PC, Acton RT, Murray JA, Leiendecker-Foster C, Snively BM, Barcellos LF, Cook JD, McLaren GD.

PLoS One. 2012;7(6):e38339. doi: 10.1371/journal.pone.0038339. Epub 2012 Jun 22.


Dietary iron intake and serum ferritin concentration in 213 patients homozygous for the HFEC282Y hemochromatosis mutation.

Gordeuk VR, Lovato L, Barton J, Vitolins M, McLaren G, Acton R, McLaren C, Harris E, Speechley M, Eckfeldt JH, Diaz S, Sholinsky P, Adams P.

Can J Gastroenterol. 2012 Jun;26(6):345-9.


Effect of ambiguous hemochromatosis gene test results on physician utilization.

Speechley M, Alter D, Guo H, Harrison H, Adams PC.

Med Care. 2012 May;50(5):394-8. doi: 10.1097/MLR.0b013e318245a06e.


Genetic testing and counseling for hereditary neurological diseases in Mali.

Meilleur KG, Coulibaly S, Traoré M, Landouré G, La Pean A, Sangaré M, Mochel F, Traoré S, Fischbeck KH, Han HR.

J Community Genet. 2011 Mar;2(1):33-42. doi: 10.1007/s12687-011-0038-0. Epub 2011 Feb 22.


Genome-wide association study identifies genetic loci associated with iron deficiency.

McLaren CE, Garner CP, Constantine CC, McLachlan S, Vulpe CD, Snively BM, Gordeuk VR, Nickerson DA, Cook JD, Leiendecker-Foster C, Beckman KB, Eckfeldt JH, Barcellos LF, Murray JA, Adams PC, Acton RT, Killeen AA, McLaren GD.

PLoS One. 2011 Mar 31;6(3):e17390. doi: 10.1371/journal.pone.0017390.


Biobanking, consent, and commercialization in international genetics research: the Type 1 Diabetes Genetics Consortium.

Hall MA, King NM, Perdue LH, Hilner JE, Akolkar B, Greenbaum CJ, McKeon C; T1DGC.

Clin Trials. 2010;7(1 Suppl):S33-45. doi: 10.1177/1740774510373492.


Tumor necrosis factor-alpha promoter variants and iron phenotypes in 785 hemochromatosis and iron overload screening (HEIRS) study participants.

Acton RT, Barton JC, Leiendecker-Foster C, Zaun C, McLaren CE, Eckfeldt JH.

Blood Cells Mol Dis. 2010 Apr 15;44(4):252-6. doi: 10.1016/j.bcmd.2010.01.007. Epub 2010 Feb 23.


Heritability of serum iron measures in the hemochromatosis and iron overload screening (HEIRS) family study.

McLaren CE, Barton JC, Eckfeldt JH, McLaren GD, Acton RT, Adams PC, Henkin LF, Gordeuk VR, Vulpe CD, Harris EL, Harrison BW, Reiss JA, Snively BM.

Am J Hematol. 2010 Feb;85(2):101-5. doi: 10.1002/ajh.21585.


Hereditary hemochromatosis: insights from the Hemochromatosis and Iron Overload Screening (HEIRS) Study.

McLaren GD, Gordeuk VR.

Hematology Am Soc Hematol Educ Program. 2009:195-206. doi: 10.1182/asheducation-2009.1.195.


Potential nonresponse bias in a clinical examination after initial screening using iron phenotyping and HFE genotyping in the hemochromatosis and iron overload screening study.

Speechley M, Barton JC, Passmore L, Harrison H, Reboussin DM, Harris EL, Rivers CA, Fadojutimi-Akinsiku M, Wenzel L, Diaz S.

Genet Test Mol Biomarkers. 2009 Dec;13(6):721-8. doi: 10.1089/gtmb.2009.0003.

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