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Items: 1 to 20 of 194

1.

Transforming growth factor β1 (TGFβ1) regulates CD44V6 expression and activity through extracellular signal-regulated kinase (ERK)-induced EGR1 in pulmonary fibrogenic fibroblasts.

Ghatak S, Markwald RR, Hascall VC, Dowling W, Lottes RG, Baatz JE, Beeson G, Beeson CC, Perrella MA, Thannickal VJ, Misra S.

J Biol Chem. 2017 Jun 23;292(25):10465-10489. doi: 10.1074/jbc.M116.752451. Epub 2017 Apr 7.

PMID:
28389562
2.

Transforming growth factor β1 (TGFβ1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis.

Ghatak S, Hascall VC, Markwald RR, Feghali-Bostwick C, Artlett CM, Gooz M, Bogatkevich GS, Atanelishvili I, Silver RM, Wood J, Thannickal VJ, Misra S.

J Biol Chem. 2017 Jun 23;292(25):10490-10519. doi: 10.1074/jbc.M116.752469. Epub 2017 Apr 7.

PMID:
28389561
3.

Oligonucleotides targeting coagulation factor mRNAs: use in thrombosis and hemophilia research and therapy.

Heestermans M, van Vlijmen BJM.

Thromb J. 2017 Mar 7;15:7. doi: 10.1186/s12959-017-0130-8. eCollection 2017. Review.

4.

Involvement of TGF-β1/Smad3 Signaling in Carbon Tetrachloride-Induced Acute Liver Injury in Mice.

Niu L, Cui X, Qi Y, Xie D, Wu Q, Chen X, Ge J, Liu Z.

PLoS One. 2016 May 25;11(5):e0156090. doi: 10.1371/journal.pone.0156090. eCollection 2016.

5.

Therapeutic nucleic acids: current clinical status.

Sridharan K, Gogtay NJ.

Br J Clin Pharmacol. 2016 Sep;82(3):659-72. doi: 10.1111/bcp.12987. Epub 2016 Jun 3. Review.

PMID:
27111518
6.

Functional genetics-directed identification of novel pharmacological inhibitors of FAS- and TNF-dependent apoptosis that protect mice from acute liver failure.

Komarov AP, Komarova EA, Green K, Novototskaya LR, Baker PS, Eroshkin A, Osterman AL, Chenchick AA, Frangou C, Gudkov AV.

Cell Death Dis. 2016 Mar 17;7:e2145. doi: 10.1038/cddis.2016.45.

7.

Tanshinone IIA ameliorates dextran sulfate sodium-induced inflammatory bowel disease via the pregnane X receptor.

Zhang X, Wang Y, Ma Z, Liang Q, Tang X, Hu D, Tan H, Xiao C, Gao Y.

Drug Des Devel Ther. 2015 Dec 7;9:6343-62. doi: 10.2147/DDDT.S79388. eCollection 2015.

8.

MiRNAs and Other Epigenetic Changes as Biomarkers in Triple Negative Breast Cancer.

Mathe A, Scott RJ, Avery-Kiejda KA.

Int J Mol Sci. 2015 Nov 30;16(12):28347-76. doi: 10.3390/ijms161226090. Review.

9.

Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases.

Matsui A, Uchida S, Ishii T, Itaka K, Kataoka K.

Sci Rep. 2015 Oct 28;5:15810. doi: 10.1038/srep15810.

10.

Knocking down disease: a progress report on siRNA therapeutics.

Wittrup A, Lieberman J.

Nat Rev Genet. 2015 Sep;16(9):543-52. doi: 10.1038/nrg3978. Review.

11.

Specific hepatic delivery of procollagen α1(I) small interfering RNA in lipid-like nanoparticles resolves liver fibrosis.

Jiménez Calvente C, Sehgal A, Popov Y, Kim YO, Zevallos V, Sahin U, Diken M, Schuppan D.

Hepatology. 2015 Oct;62(4):1285-97. doi: 10.1002/hep.27936. Epub 2015 Aug 28.

12.

Delivery of siRNA to ovarian cancer cells using laser-activated carbon nanoparticles.

Sengupta A, Mezencev R, McDonald JF, Prausnitz MR.

Nanomedicine (Lond). 2015;10(11):1775-84. doi: 10.2217/nnm.15.27.

13.

Inducing gene expression by targeting promoter sequences using small activating RNAs.

Wang J, Place RF, Portnoy V, Huang V, Kang MR, Kosaka M, Ho MK, Li LC.

J Biol Methods. 2015 Mar 11;2(1). pii: e14.

14.

Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference.

Barrangou R, Birmingham A, Wiemann S, Beijersbergen RL, Hornung V, Smith Av.

Nucleic Acids Res. 2015 Apr 20;43(7):3407-19. doi: 10.1093/nar/gkv226. Epub 2015 Mar 23. Review.

16.

Effects of Zhichan powder on signal transduction and apoptosis-associated gene expression in the substantia nigra of Parkinson's disease rats.

Chen J, Ma J, Qiu Y, Yi S, Liu Y, Zhou Q, Zhang P, Wan Q, Kuang Y.

Neural Regen Res. 2012 Sep 25;7(27):2115-22. doi: 10.3969/j.issn.1673-5374.2012.27.005.

17.

CYLD deletion triggers nuclear factor-κB-signaling and increases cell death resistance in murine hepatocytes.

Urbanik T, Koehler BC, Wolpert L, Elßner C, Scherr AL, Longerich T, Kautz N, Welte S, Hövelmeyer N, Jäger D, Waisman A, Schulze-Bergkamen H.

World J Gastroenterol. 2014 Dec 7;20(45):17049-64. doi: 10.3748/wjg.v20.i45.17049.

18.

Lentivirus mediated siRNA against GluN2B subunit of NMDA receptor reduces nociception in a rat model of neuropathic pain.

Wu F, Pan R, Chen J, Sugita M, Chen C, Tao Y, Yu W, Sun Y.

Biomed Res Int. 2014;2014:871637. doi: 10.1155/2014/871637. Epub 2014 Aug 28.

19.

Design and evaluation of thioalkylated mannose-modified dendrimer (G3)/α-cyclodextrin conjugates as antigen-presenting cell-selective siRNA carriers.

Motoyama K, Mitsuyasu R, Akao C, Tanaka T, Ohyama A, Sato N, Higashi T, Arima H.

AAPS J. 2014 Nov;16(6):1298-308. doi: 10.1208/s12248-014-9665-9. Epub 2014 Sep 19.

20.

Inhibitory effect of liposomal quercetin on acute hepatitis and hepatic fibrosis induced by concanavalin A.

Wan Y, Tang MH, Chen XC, Chen LJ, Wei YQ, Wang YS.

Braz J Med Biol Res. 2014 Aug;47(8):655-61.

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