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Items: 1 to 20 of 68


Blockade of alcohol escalation and "relapse" drinking by pharmacological FAAH inhibition in male and female C57BL/6J mice.

Zhou Y, Schwartz BI, Giza J, Gross SS, Lee FS, Kreek MJ.

Psychopharmacology (Berl). 2017 Oct;234(19):2955-2970. doi: 10.1007/s00213-017-4691-9. Epub 2017 Jul 20.


Mice expressing a "hyper-sensitive" form of the CB1 cannabinoid receptor (CB1) show modestly enhanced alcohol preference and consumption.

Marcus DJ, Henderson-Redmond AN, Gonek M, Zee ML, Farnsworth JC, Amin RA, Andrews MJ, Davis BJ, Mackie K, Morgan DJ.

PLoS One. 2017 Apr 20;12(4):e0174826. doi: 10.1371/journal.pone.0174826. eCollection 2017.


Changes in the Brain Endocannabinoid System in Rat Models of Depression.

Smaga I, Jastrzębska J, Zaniewska M, Bystrowska B, Gawliński D, Faron-Górecka A, Broniowska Ż, Miszkiel J, Filip M.

Neurotox Res. 2017 Apr;31(3):421-435. doi: 10.1007/s12640-017-9708-y. Epub 2017 Feb 28.


Severity of alcohol dependence is associated with the fatty acid amide hydrolase Pro129Thr missense variant.

Sloan ME, Gowin JL, Yan J, Schwandt ML, Spagnolo PA, Sun H, Hodgkinson CA, Goldman D, Ramchandani VA.

Addict Biol. 2017 Feb 1. doi: 10.1111/adb.12491. [Epub ahead of print]


Regional Influence of Cannabinoid CB1 Receptors in the Regulation of Ethanol Self-Administration by Wistar Rats.

Alvarez-Jaimes L, Polis I, Parsons LH.

Open Neuropsychopharmacol J. 2009;2:77-85.


Broad impact of deleting endogenous cannabinoid hydrolyzing enzymes and the CB1 cannabinoid receptor on the endogenous cannabinoid-related lipidome in eight regions of the mouse brain.

Leishman E, Cornett B, Spork K, Straiker A, Mackie K, Bradshaw HB.

Pharmacol Res. 2016 Aug;110:159-172. doi: 10.1016/j.phrs.2016.04.020. Epub 2016 Apr 22.


Genes and Alcohol Consumption: Studies with Mutant Mice.

Mayfield J, Arends MA, Harris RA, Blednov YA.

Int Rev Neurobiol. 2016;126:293-355. doi: 10.1016/bs.irn.2016.02.014. Review.


Involvement of Endocannabinoids in Alcohol "Binge" Drinking: Studies of Mice with Human Fatty Acid Amide Hydrolase Genetic Variation and After CB1 Receptor Antagonists.

Zhou Y, Huang T, Lee F, Kreek MJ.

Alcohol Clin Exp Res. 2016 Mar;40(3):467-73. doi: 10.1111/acer.12989. Epub 2016 Feb 9.


Genetic Versus Pharmacological Assessment of the Role of Cannabinoid Type 2 Receptors in Alcohol Reward-Related Behaviors.

Powers MS, Breit KR, Chester JA.

Alcohol Clin Exp Res. 2015 Dec;39(12):2438-46. doi: 10.1111/acer.12894.


Critical needs in drug discovery for cessation of alcohol and nicotine polysubstance abuse.

Van Skike CE, Maggio SE, Reynolds AR, Casey EM, Bardo MT, Dwoskin LP, Prendergast MA, Nixon K.

Prog Neuropsychopharmacol Biol Psychiatry. 2016 Feb 4;65:269-87. doi: 10.1016/j.pnpbp.2015.11.004. Epub 2015 Nov 12. Review.


Chronic ethanol exposure increases voluntary home cage intake in adult male, but not female, Long-Evans rats.

Morales M, McGinnis MM, McCool BA.

Pharmacol Biochem Behav. 2015 Dec;139(Pt A):67-76. doi: 10.1016/j.pbb.2015.10.016. Epub 2015 Oct 26.


Pharmacological activation of CB2 receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the adult rat brain.

Rivera P, Blanco E, Bindila L, Alen F, Vargas A, Rubio L, Pavón FJ, Serrano A, Lutz B, Rodríguez de Fonseca F, Suárez J.

Front Cell Neurosci. 2015 Sep 29;9:379. doi: 10.3389/fncel.2015.00379. eCollection 2015.


Roles for the endocannabinoid system in ethanol-motivated behavior.

Henderson-Redmond AN, Guindon J, Morgan DJ.

Prog Neuropsychopharmacol Biol Psychiatry. 2016 Feb 4;65:330-9. doi: 10.1016/j.pnpbp.2015.06.011. Epub 2015 Jun 26. Review.


Endocannabinoid 2-Arachidonoylglycerol Self-Administration by Sprague-Dawley Rats and Stimulation of in vivo Dopamine Transmission in the Nucleus Accumbens Shell.

De Luca MA, Valentini V, Bimpisidis Z, Cacciapaglia F, Caboni P, Di Chiara G.

Front Psychiatry. 2014 Oct 17;5:140. doi: 10.3389/fpsyt.2014.00140. eCollection 2014.


Habitual alcohol seeking: modeling the transition from casual drinking to addiction.

Barker JM, Taylor JR.

Neurosci Biobehav Rev. 2014 Nov;47:281-94. doi: 10.1016/j.neubiorev.2014.08.012. Epub 2014 Sep 2. Review.


Interrelationship of CB1R and OBR pathways in regulation of metabolic, neuroendocrine, and behavioral responses to food restriction and voluntary wheel running.

Diane A, Vine DF, Russell JC, Heth CD, Pierce WD, Proctor SD.

J Appl Physiol (1985). 2014 Jul 15;117(2):97-104. doi: 10.1152/japplphysiol.01303.2013. Epub 2014 Jun 5.


Cannabinoid-hypocretin cross-talk in the central nervous system: what we know so far.

Flores A, Maldonado R, Berrendero F.

Front Neurosci. 2013 Dec 20;7:256. doi: 10.3389/fnins.2013.00256. Review.


Translational strategies for therapeutic development in nicotine addiction: rethinking the conventional bench to bedside approach.

Le Foll B, Pushparaj A, Pryslawsky Y, Forget B, Vemuri K, Makriyannis A, Trigo JM.

Prog Neuropsychopharmacol Biol Psychiatry. 2014 Jul 3;52:86-93. doi: 10.1016/j.pnpbp.2013.10.009. Epub 2013 Oct 17. Review.


Design, synthesis, and biological evaluation of aminoalkylindole derivatives as cannabinoid receptor ligands with potential for treatment of alcohol abuse.

Vasiljevik T, Franks LN, Ford BM, Douglas JT, Prather PL, Fantegrossi WE, Prisinzano TE.

J Med Chem. 2013 Jun 13;56(11):4537-50. doi: 10.1021/jm400268b. Epub 2013 May 22.

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