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Histone H4 is cleaved by granzyme A during staurosporine-induced cell death in B-lymphoid Raji cells.

Lee PY, Park BC, Chi SW, Bae KH, Kim S, Cho S, Kang S, Kim JH, Park SG.

BMB Rep. 2016 Oct;49(10):560-565.


Peroxiredoxin 1 interacts with and blocks the redox factor APE1 from activating interleukin-8 expression.

Nassour H, Wang Z, Saad A, Papaluca A, Brosseau N, Affar el B, Alaoui-Jamali MA, Ramotar D.

Sci Rep. 2016 Jul 8;6:29389. doi: 10.1038/srep29389.


Regulation of limited N-terminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation.

Bhakat KK, Sengupta S, Adeniyi VF, Roychoudhury S, Nath S, Bellot LJ, Feng D, Mantha AK, Sinha M, Qiu S, Luxon BA.

Oncotarget. 2016 Apr 19;7(16):22590-604. doi: 10.18632/oncotarget.8026.


Phytoconstituents as apoptosis inducing agents: strategy to combat cancer.

Kumar M, Kaur V, Kumar S, Kaur S.

Cytotechnology. 2016 Aug;68(4):531-63. doi: 10.1007/s10616-015-9897-2. Epub 2015 Aug 4. Review.


Apurinic/apyrimidinic endonuclease/redox factor-1 (APE1/Ref-1) redox function negatively regulates NRF2.

Fishel ML, Wu X, Devlin CM, Logsdon DP, Jiang Y, Luo M, He Y, Yu Z, Tong Y, Lipking KP, Maitra A, Rajeshkumar NV, Scandura G, Kelley MR, Ivan M.

J Biol Chem. 2015 Jan 30;290(5):3057-68. doi: 10.1074/jbc.M114.621995. Epub 2014 Dec 9.


Recognition and repair of chemically heterogeneous structures at DNA ends.

Andres SN, Schellenberg MJ, Wallace BD, Tumbale P, Williams RS.

Environ Mol Mutagen. 2015 Jan;56(1):1-21. doi: 10.1002/em.21892. Epub 2014 Aug 11. Review.


Regulatory mechanisms of RNA function: emerging roles of DNA repair enzymes.

Jobert L, Nilsen H.

Cell Mol Life Sci. 2014 Jul;71(13):2451-65. doi: 10.1007/s00018-014-1562-y. Epub 2014 Feb 5. Review.


Repair of oxidative DNA damage and cancer: recent progress in DNA base excision repair.

Scott TL, Rangaswamy S, Wicker CA, Izumi T.

Antioxid Redox Signal. 2014 Feb 1;20(4):708-26. doi: 10.1089/ars.2013.5529. Epub 2013 Oct 15. Review.


Human apurinic/apyrimidinic endonuclease 1.

Li M, Wilson DM 3rd.

Antioxid Redox Signal. 2014 Feb 1;20(4):678-707. doi: 10.1089/ars.2013.5492. Epub 2013 Aug 20. Review.


Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis.

Susanto O, Stewart SE, Voskoboinik I, Brasacchio D, Hagn M, Ellis S, Asquith S, Sedelies KA, Bird PI, Waterhouse NJ, Trapani JA.

Cell Death Differ. 2013 Sep;20(9):1183-93. doi: 10.1038/cdd.2013.59. Epub 2013 Jun 7.


Differential expression of hepatic apurinic/apyrimidinic endonuclease 1, a DNA repair enzyme, in chronic hepatitis.

Sumiyoshi S, Kobayashi Y, Kawamura K, Kawata K, Nakamura H.

World J Hepatol. 2013 Apr 27;5(4):206-13. doi: 10.4254/wjh.v5.i4.206.


Human NK cell lytic granules and regulation of their exocytosis.

Krzewski K, Coligan JE.

Front Immunol. 2012 Nov 9;3:335. doi: 10.3389/fimmu.2012.00335. eCollection 2012.


Recruitment of Grb2 and SHIP1 by the ITT-like motif of TIGIT suppresses granule polarization and cytotoxicity of NK cells.

Liu S, Zhang H, Li M, Hu D, Li C, Ge B, Jin B, Fan Z.

Cell Death Differ. 2013 Mar;20(3):456-64. doi: 10.1038/cdd.2012.141. Epub 2012 Nov 16.


APE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1-STAT3 dual-targeting effectively inhibits pancreatic cancer cell survival.

Cardoso AA, Jiang Y, Luo M, Reed AM, Shahda S, He Y, Maitra A, Kelley MR, Fishel ML.

PLoS One. 2012;7(10):e47462. doi: 10.1371/journal.pone.0047462. Epub 2012 Oct 19.


Viscum album L. Extracts Protects HeLa Cells against Nuclear and Mitochondrial DNA Damage.

Onay-Uçar E, Erol O, Kandemir B, Mertoğlu E, Karagöz A, Arda N.

Evid Based Complement Alternat Med. 2012;2012:958740. doi: 10.1155/2012/958740. Epub 2012 Aug 16.


Nuclear depletion of apurinic/apyrimidinic endonuclease 1 (Ape1/Ref-1) is an indicator of energy disruption in neurons.

Singh S, Englander EW.

Free Radic Biol Med. 2012 Nov 1;53(9):1782-90. doi: 10.1016/j.freeradbiomed.2012.07.025. Epub 2012 Jul 27.


Characterizing the efficacy of fermented wheat germ extract against ovarian cancer and defining the genomic basis of its activity.

Judson PL, Al Sawah E, Marchion DC, Xiong Y, Bicaku E, Bou Zgheib N, Chon HS, Stickles XB, Hakam A, Wenham RM, Apte SM, Gonzalez-Bosquet J, Chen DT, Lancaster JM.

Int J Gynecol Cancer. 2012 Jul;22(6):960-7. doi: 10.1097/IGC.0b013e318258509d.


All human granzymes target hnRNP K that is essential for tumor cell viability.

van Domselaar R, Quadir R, van der Made AM, Broekhuizen R, Bovenschen N.

J Biol Chem. 2012 Jun 29;287(27):22854-64. doi: 10.1074/jbc.M112.365692. Epub 2012 May 11.


Molecular mechanisms for age-associated mitochondrial deficiency in skeletal muscle.

Wagatsuma A, Sakuma K.

J Aging Res. 2012;2012:768304. doi: 10.1155/2012/768304. Epub 2012 Apr 4.

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