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Items: 15


Hepatitis C virus NS3 protein enhances hepatocellular carcinoma cell invasion by promoting PPM1A ubiquitination and degradation.

Zhou Y, Zhao Y, Gao Y, Hu W, Qu Y, Lou N, Zhu Y, Zhang X, Yang H.

J Exp Clin Cancer Res. 2017 Mar 10;36(1):42. doi: 10.1186/s13046-017-0510-8.


Inhibition of RUNX2 transcriptional activity blocks the proliferation, migration and invasion of epithelial ovarian carcinoma cells.

Wang ZQ, Keita M, Bachvarova M, Gobeil S, Morin C, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Trinh XB, Bachvarov D.

PLoS One. 2013 Oct 4;8(10):e74384. doi: 10.1371/journal.pone.0074384.


Binding of a third metal ion by the human phosphatases PP2Cα and Wip1 is required for phosphatase activity.

Tanoue K, Miller Jenkins LM, Durell SR, Debnath S, Sakai H, Tagad HD, Ishida K, Appella E, Mazur SJ.

Biochemistry. 2013 Aug 27;52(34):5830-43. doi: 10.1021/bi4005649.


Cadmium is a potent inhibitor of PPM phosphatases and targets the M1 binding site.

Pan C, Liu HD, Gong Z, Yu X, Hou XB, Xie DD, Zhu XB, Li HW, Tang JY, Xu YF, Yu JQ, Zhang LY, Fang H, Xiao KH, Chen YG, Wang JY, Pang Q, Chen W, Sun JP.

Sci Rep. 2013;3:2333. doi: 10.1038/srep02333.


Gene, pathway and network frameworks to identify epistatic interactions of single nucleotide polymorphisms derived from GWAS data.

Liu Y, Maxwell S, Feng T, Zhu X, Elston RC, Koyutürk M, Chance MR.

BMC Syst Biol. 2012;6 Suppl 3:S15. doi: 10.1186/1752-0509-6-S3-S15.


Protein phosphatase magnesium dependent 1A (PPM1A) plays a role in the differentiation and survival processes of nerve cells.

Shohat M, Ben-Meir D, Lavi S.

PLoS One. 2012;7(2):e32438. doi: 10.1371/journal.pone.0032438.


Activation of protein serine/threonine phosphatase PP2Cα efficiently prevents liver fibrosis.

Wang L, Wang X, Chen J, Yang Z, Yu L, Hu L, Shen X.

PLoS One. 2010 Dec 6;5(12):e14230. doi: 10.1371/journal.pone.0014230.


p53-mediated apoptosis requires inositol hexakisphosphate kinase-2.

Koldobskiy MA, Chakraborty A, Werner JK Jr, Snowman AM, Juluri KR, Vandiver MS, Kim S, Heletz S, Snyder SH.

Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):20947-51. doi: 10.1073/pnas.1015671107.


Type 2C protein phosphatases in fungi.

Ariño J, Casamayor A, González A.

Eukaryot Cell. 2011 Jan;10(1):21-33. doi: 10.1128/EC.00249-10. Review.


Microarray analysis of Shigella flexneri-infected epithelial cells identifies host factors important for apoptosis inhibition.

Faherty CS, Merrell DS, Semino-Mora C, Dubois A, Ramaswamy AV, Maurelli AT.

BMC Genomics. 2010 Apr 29;11:272. doi: 10.1186/1471-2164-11-272.


Genomewide RNA expression profiling in lung identifies distinct signatures in idiopathic pulmonary arterial hypertension and secondary pulmonary hypertension.

Rajkumar R, Konishi K, Richards TJ, Ishizawar DC, Wiechert AC, Kaminski N, Ahmad F.

Am J Physiol Heart Circ Physiol. 2010 Apr;298(4):H1235-48. doi: 10.1152/ajpheart.00254.2009.


Zinc deficiency alters DNA damage response genes in normal human prostate epithelial cells.

Yan M, Song Y, Wong CP, Hardin K, Ho E.

J Nutr. 2008 Apr;138(4):667-73.


Role of PP2Calpha in cell growth, in radio- and chemosensitivity, and in tumorigenicity.

Lammers T, Peschke P, Ehemann V, Debus J, Slobodin B, Lavi S, Huber P.

Mol Cancer. 2007 Oct 17;6:65.


p90 ribosomal S6 kinase 2 is associated with and dephosphorylated by protein phosphatase 2Cdelta.

Doehn U, Gammeltoft S, Shen SH, Jensen CJ.

Biochem J. 2004 Sep 1;382(Pt 2):425-31.

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