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Items: 1 to 20 of 26

1.

Prostaglandin E2 Inhibits Histamine-Evoked Ca2+ Release in Human Aortic Smooth Muscle Cells through Hyperactive cAMP Signaling Junctions and Protein Kinase A.

Taylor EJA, Pantazaka E, Shelley KL, Taylor CW.

Mol Pharmacol. 2017 Nov;92(5):533-545. doi: 10.1124/mol.117.109249. Epub 2017 Sep 6.

2.

International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases.

Dessauer CW, Watts VJ, Ostrom RS, Conti M, Dove S, Seifert R.

Pharmacol Rev. 2017 Apr;69(2):93-139. doi: 10.1124/pr.116.013078. Review.

PMID:
28255005
3.

Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties.

Brust TF, Alongkronrusmee D, Soto-Velasquez M, Baldwin TA, Ye Z, Dai M, Dessauer CW, van Rijn RM, Watts VJ.

Sci Signal. 2017 Feb 21;10(467). pii: eaah5381. doi: 10.1126/scisignal.aah5381.

4.

Bioinformatics analysis of the molecular mechanism of diffuse intrinsic pontine glioma.

Deng L, Xiong P, Luo Y, Bu X, Qian S, Zhong W.

Oncol Lett. 2016 Oct;12(4):2524-2530. Epub 2016 Aug 16.

5.

Spilanthol from Acmella Oleracea Lowers the Intracellular Levels of cAMP Impairing NKCC2 Phosphorylation and Water Channel AQP2 Membrane Expression in Mouse Kidney.

Gerbino A, Schena G, Milano S, Milella L, Barbosa AF, Armentano F, Procino G, Svelto M, Carmosino M.

PLoS One. 2016 May 23;11(5):e0156021. doi: 10.1371/journal.pone.0156021. eCollection 2016.

6.

Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

Li YR, Li J, Zhao SD, Bradfield JP, Mentch FD, Maggadottir SM, Hou C, Abrams DJ, Chang D, Gao F, Guo Y, Wei Z, Connolly JJ, Cardinale CJ, Bakay M, Glessner JT, Li D, Kao C, Thomas KA, Qiu H, Chiavacci RM, Kim CE, Wang F, Snyder J, Richie MD, Flatø B, Førre Ø, Denson LA, Thompson SD, Becker ML, Guthery SL, Latiano A, Perez E, Resnick E, Russell RK, Wilson DC, Silverberg MS, Annese V, Lie BA, Punaro M, Dubinsky MC, Monos DS, Strisciuglio C, Staiano A, Miele E, Kugathasan S, Ellis JA, Munro JE, Sullivan KE, Wise CA, Chapel H, Cunningham-Rundles C, Grant SF, Orange JS, Sleiman PM, Behrens EM, Griffiths AM, Satsangi J, Finkel TH, Keinan A, Prak ET, Polychronakos C, Baldassano RN, Li H, Keating BJ, Hakonarson H.

Nat Med. 2015 Sep;21(9):1018-27. doi: 10.1038/nm.3933. Epub 2015 Aug 24.

7.

Genome-wide association study of height-adjusted BMI in childhood identifies functional variant in ADCY3.

Stergiakouli E, Gaillard R, Tavaré JM, Balthasar N, Loos RJ, Taal HR, Evans DM, Rivadeneira F, St Pourcain B, Uitterlinden AG, Kemp JP, Hofman A, Ring SM, Cole TJ, Jaddoe VW, Davey Smith G, Timpson NJ.

Obesity (Silver Spring). 2014 Oct;22(10):2252-9. doi: 10.1002/oby.20840. Epub 2014 Jul 21.

8.

The genetic basis of music ability.

Tan YT, McPherson GE, Peretz I, Berkovic SF, Wilson SJ.

Front Psychol. 2014 Jun 27;5:658. doi: 10.3389/fpsyg.2014.00658. eCollection 2014. Review.

9.

Genes involved in type 1 diabetes: an update.

Bakay M, Pandey R, Hakonarson H.

Genes (Basel). 2013 Sep 16;4(3):499-521. doi: 10.3390/genes4030499.

10.

Gap junction modulation and its implications for heart function.

Kurtenbach S, Kurtenbach S, Zoidl G.

Front Physiol. 2014 Feb 27;5:82. doi: 10.3389/fphys.2014.00082. eCollection 2014. Review.

11.

Development of a high-throughput screening paradigm for the discovery of small-molecule modulators of adenylyl cyclase: identification of an adenylyl cyclase 2 inhibitor.

Conley JM, Brand CS, Bogard AS, Pratt EP, Xu R, Hockerman GH, Ostrom RS, Dessauer CW, Watts VJ.

J Pharmacol Exp Ther. 2013 Nov;347(2):276-87. doi: 10.1124/jpet.113.207449. Epub 2013 Sep 5.

12.

Similarly potent inhibition of adenylyl cyclase by P-site inhibitors in hearts from wild type and AC5 knockout mice.

Braeunig JH, Schweda F, Han PL, Seifert R.

PLoS One. 2013 Jul 1;8(7):e68009. doi: 10.1371/journal.pone.0068009. Print 2013.

13.

The role of mislocalized phototransduction in photoreceptor cell death of retinitis pigmentosa.

Nakao T, Tsujikawa M, Notomi S, Ikeda Y, Nishida K.

PLoS One. 2012;7(4):e32472. doi: 10.1371/journal.pone.0032472. Epub 2012 Apr 2.

14.

CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in Poland.

Hardin M, Zielinski J, Wan ES, Hersh CP, Castaldi PJ, Schwinder E, Hawrylkiewicz I, Sliwinski P, Cho MH, Silverman EK.

Am J Respir Cell Mol Biol. 2012 Aug;47(2):203-8. doi: 10.1165/rcmb.2012-0011OC. Epub 2012 Mar 29.

15.

Parathyroid hormone signaling via Gαs is selectively inhibited by an NH(2)-terminally truncated Gαs: implications for pseudohypoparathyroidism.

Puzhko S, Goodyer CG, Kerachian MA, Canaff L, Misra M, Jüppner H, Bastepe M, Hendy GN.

J Bone Miner Res. 2011 Oct;26(10):2473-85. doi: 10.1002/jbmr.461.

16.

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.

Freathy RM, Mook-Kanamori DO, Sovio U, Prokopenko I, Timpson NJ, Berry DJ, Warrington NM, Widen E, Hottenga JJ, Kaakinen M, Lange LA, Bradfield JP, Kerkhof M, Marsh JA, Mägi R, Chen CM, Lyon HN, Kirin M, Adair LS, Aulchenko YS, Bennett AJ, Borja JB, Bouatia-Naji N, Charoen P, Coin LJ, Cousminer DL, de Geus EJ, Deloukas P, Elliott P, Evans DM, Froguel P; Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Glaser B, Groves CJ, Hartikainen AL, Hassanali N, Hirschhorn JN, Hofman A, Holly JM, Hyppönen E, Kanoni S, Knight BA, Laitinen J, Lindgren CM; Meta-Analyses of Glucose and Insulin-related traits Consortium, McArdle WL, O'Reilly PF, Pennell CE, Postma DS, Pouta A, Ramasamy A, Rayner NW, Ring SM, Rivadeneira F, Shields BM, Strachan DP, Surakka I, Taanila A, Tiesler C, Uitterlinden AG, van Duijn CM; Wellcome Trust Case Control Consortium, Wijga AH, Willemsen G, Zhang H, Zhao J, Wilson JF, Steegers EA, Hattersley AT, Eriksson JG, Peltonen L, Mohlke KL, Grant SF, Hakonarson H, Koppelman GH, Dedoussis GV, Heinrich J, Gillman MW, Palmer LJ, Frayling TM, Boomsma DI, Davey Smith G, Power C, Jaddoe VW, Jarvelin MR; Early Growth Genetics (EGG) Consortium, McCarthy MI.

Nat Genet. 2010 May;42(5):430-5. doi: 10.1038/ng.567. Epub 2010 Apr 6.

17.

Genome-wide study of families with absolute pitch reveals linkage to 8q24.21 and locus heterogeneity.

Theusch E, Basu A, Gitschier J.

Am J Hum Genet. 2009 Jul;85(1):112-9. doi: 10.1016/j.ajhg.2009.06.010. Epub 2009 Jul 2.

18.

The actin cytoskeleton in endothelial cell phenotypes.

Prasain N, Stevens T.

Microvasc Res. 2009 Jan;77(1):53-63. doi: 10.1016/j.mvr.2008.09.012. Epub 2008 Oct 26. Review.

19.

The C1 and C2 domains target human type 6 adenylyl cyclase to lipid rafts and caveolae.

Thangavel M, Liu X, Sun SQ, Kaminsky J, Ostrom RS.

Cell Signal. 2009 Feb;21(2):301-8. doi: 10.1016/j.cellsig.2008.10.017. Epub 2008 Nov 5.

20.

Selective coupling of type 6 adenylyl cyclase with type 2 IP3 receptors mediates direct sensitization of IP3 receptors by cAMP.

Tovey SC, Dedos SG, Taylor EJ, Church JE, Taylor CW.

J Cell Biol. 2008 Oct 20;183(2):297-311. doi: 10.1083/jcb.200803172.

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