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Items: 13


Acetaminophen cytotoxicity is ameliorated in a human liver organotypic co-culture model.

Nelson LJ, Navarro M, Treskes P, Samuel K, Tura-Ceide O, Morley SD, Hayes PC, Plevris JN.

Sci Rep. 2015 Dec 3;5:17455. doi: 10.1038/srep17455.


Remediation of hemorrhagic shock-induced intestinal barrier dysfunction by treatment with diphenyldihaloketones EF24 and CLEFMA.

Yadav VR, Hussain A, Sahoo K, Awasthi V.

J Pharmacol Exp Ther. 2014 Nov;351(2):413-22. doi: 10.1124/jpet.114.217331.


Protective effect of bone marrow mesenchymal stem cells in intestinal barrier permeability after heterotopic intestinal transplantation.

Zhang W, Shen ZY, Song HL, Yang Y, Wu BJ, Fu NN, Liu T.

World J Gastroenterol. 2014 Jun 21;20(23):7442-51. doi: 10.3748/wjg.v20.i23.7442.


In Vivo and In Vitro Antinociceptive Effect of Fagopyrum cymosum (Trev.) Meisn Extracts: A Possible Action by Recovering Intestinal Barrier Dysfunction.

Liu L, Cai X, Yan J, Luo Y, Shao M, Lu Y, Sun Z, Cao P.

Evid Based Complement Alternat Med. 2012;2012:983801. doi: 10.1155/2012/983801.


Ethyl pyruvate reduces liver injury at early phase but impairs regeneration at late phase in acetaminophen overdose.

Yang R, Zou X, Koskinen ML, Tenhunen J.

Crit Care. 2012 Jan 16;16(1):R9. doi: 10.1186/cc11149.


Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis.

Fredenburgh LE, Velandia MM, Ma J, Olszak T, Cernadas M, Englert JA, Chung SW, Liu X, Begay C, Padera RF, Blumberg RS, Walsh SR, Baron RM, Perrella MA.

J Immunol. 2011 Nov 15;187(10):5255-67. doi: 10.4049/jimmunol.1101186.


Ethyl pyruvate prevents inflammatory responses and organ damage during resuscitation in porcine hemorrhage.

Dong W, Cai B, Peña G, Pisarenko V, Vida G, Doucet D, Lee M, Sharpe S, Lu Q, Xu DZ, Ramos L, Deitch EA, Ulloa L.

Shock. 2010 Aug;34(2):205-13. doi: 10.1097/SHK.0b013e3181cc0c63.


Ethyl pyruvate reduces mortality in an endotoxin-induced severe acute lung injury mouse model.

Shang GH, Lin DJ, Xiao W, Jia CQ, Li Y, Wang AH, Dong L.

Respir Res. 2009 Oct 2;10:91. doi: 10.1186/1465-9921-10-91.


Can we predict the effects of NF-kappaB inhibition in sepsis? Studies with parthenolide and ethyl pyruvate.

Li X, Su J, Cui X, Li Y, Barochia A, Eichacker PQ.

Expert Opin Investig Drugs. 2009 Aug;18(8):1047-60. doi: 10.1517/13543780903018880. Review.


Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.

Davé SH, Tilstra JS, Matsuoka K, Li F, DeMarco RA, Beer-Stolz D, Sepulveda AR, Fink MP, Lotze MT, Plevy SE.

J Leukoc Biol. 2009 Sep;86(3):633-43. doi: 10.1189/jlb.1008662.


Treatment with a novel hemigramicidin-TEMPO conjugate prolongs survival in a rat model of lethal hemorrhagic shock.

Macias CA, Chiao JW, Xiao J, Arora DS, Tyurina YY, Delude RL, Wipf P, Kagan VE, Fink MP.

Ann Surg. 2007 Feb;245(2):305-14.

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