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GM-CSF in murine psoriasiform dermatitis: Redundant and pathogenic roles uncovered by antibody-induced neutralization and genetic deficiency.

Scholz T, Weigert A, Brüne B, Sadik CD, Böhm B, Burkhardt H.

PLoS One. 2017 Aug 4;12(8):e0182646. doi: 10.1371/journal.pone.0182646. eCollection 2017.


Cancer Vaccines in Ovarian Cancer: How Can We Improve?

Martin Lluesma S, Wolfer A, Harari A, Kandalaft LE.

Biomedicines. 2016 May 3;4(2). pii: E10. doi: 10.3390/biomedicines4020010. Review.


Hematopoietic stem cell-derived myeloid and plasmacytoid DC-based vaccines are highly potent inducers of tumor-reactive T cell and NK cell responses ex vivo.

Thordardottir S, Schaap N, Louer E, Kester MG, Falkenburg JH, Jansen J, Radstake TR, Hobo W, Dolstra H.

Oncoimmunology. 2017 Feb 6;6(3):e1285991. doi: 10.1080/2162402X.2017.1285991. eCollection 2017.


TSG-6 Downregulates IFN-Alpha and TNF-Alpha Expression by Suppressing IRF7 Phosphorylation in Human Plasmacytoid Dendritic Cells.

Kui L, Chan GC, Lee PP.

Mediators Inflamm. 2017;2017:7462945. doi: 10.1155/2017/7462945. Epub 2017 Mar 6.


The Immunomodulatory Small Molecule Imiquimod Induces Apoptosis in Devil Facial Tumour Cell Lines.

Patchett AL, Darby JM, Tovar C, Lyons AB, Woods GM.

PLoS One. 2016 Dec 9;11(12):e0168068. doi: 10.1371/journal.pone.0168068. eCollection 2016.


Innate immunity based cancer immunotherapy: B16-F10 murine melanoma model.

Caisová V, Vieru A, Kumžáková Z, Glaserová S, Husníková H, Vácová N, Krejčová G, Paďouková L, Jochmanová I, Wolf KI, Chmelař J, Kopecký J, Ženka J.

BMC Cancer. 2016 Dec 7;16(1):940.


TLR-7 activation enhances IL-22-mediated colonization resistance against vancomycin-resistant enterococcus.

Abt MC, Buffie CG, Sušac B, Becattini S, Carter RA, Leiner I, Keith JW, Artis D, Osborne LC, Pamer EG.

Sci Transl Med. 2016 Feb 24;8(327):327ra25. doi: 10.1126/scitranslmed.aad6663.


Molecular Determinants of GS-9620-Dependent TLR7 Activation.

Rebbapragada I, Birkus G, Perry J, Xing W, Kwon H, Pflanz S.

PLoS One. 2016 Jan 19;11(1):e0146835. doi: 10.1371/journal.pone.0146835. eCollection 2016.


Effects of Human Mesenchymal Stem Cells Transduced with Superoxide Dismutase on Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice.

Sah SK, Park KH, Yun CO, Kang KS, Kim TY.

Antioxid Redox Signal. 2016 Feb 10;24(5):233-48. doi: 10.1089/ars.2015.6368. Epub 2015 Nov 18.


The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes.

Richards KH, Wasson CW, Watherston O, Doble R, Blair GE, Wittmann M, Macdonald A.

Sci Rep. 2015 Aug 13;5:12922. doi: 10.1038/srep12922.


Topical resiquimod can induce disease regression and enhance T-cell effector functions in cutaneous T-cell lymphoma.

Rook AH, Gelfand JM, Wysocka M, Troxel AB, Benoit B, Surber C, Elenitsas R, Buchanan MA, Leahy DS, Watanabe R, Kirsch IR, Kim EJ, Clark RA.

Blood. 2015 Sep 17;126(12):1452-61. doi: 10.1182/blood-2015-02-630335. Epub 2015 Jul 30. Erratum in: Blood. 2015 Dec 17;126(25):2765. Gelfand, Joel C [corrected to Gelfand, Joel M].


A conjugate of octamer-binding transcription factor 4 and toll-like receptor 7 agonist prevents the growth and metastasis of testis embryonic carcinoma.

Lin G, Wang X, Yi W, Zhang C, Xu G, Zhu X, Cai Z, Liu Y, Diao Y, Lin MC, Jin G.

J Transl Med. 2015 May 20;13:166. doi: 10.1186/s12967-015-0524-y.


HIV-1 single-stranded RNA induces CXCL13 secretion in human monocytes via TLR7 activation and plasmacytoid dendritic cell-derived type I IFN.

Cohen KW, Dugast AS, Alter G, McElrath MJ, Stamatatos L.

J Immunol. 2015 Mar 15;194(6):2769-75. doi: 10.4049/jimmunol.1400952. Epub 2015 Feb 9.


Melanoma arising after imiquimod use.

Paul SP.

Case Rep Med. 2014;2014:267535. doi: 10.1155/2014/267535. Epub 2014 Nov 9.


A micro-sterile inflammation array as an adjuvant for influenza vaccines.

Wang J, Shah D, Chen X, Anderson RR, Wu MX.

Nat Commun. 2014 Jul 18;5:4447. doi: 10.1038/ncomms5447.


Topical resiquimod protects against visceral infection with Leishmania infantum chagasi in mice.

Craft N, Birnbaum R, Quanquin N, Erfe MC, Quant C, Haskell J, Bruhn KW.

Clin Vaccine Immunol. 2014 Sep;21(9):1314-22. doi: 10.1128/CVI.00338-14. Epub 2014 Jul 16.


Post-transcriptional regulation of interferons and their signaling pathways.

Savan R.

J Interferon Cytokine Res. 2014 May;34(5):318-29. doi: 10.1089/jir.2013.0117. Epub 2014 Apr 4. Review.


Toll-like receptor 7 agonist imiquimod in combination with influenza vaccine expedites and augments humoral immune responses against influenza A(H1N1)pdm09 virus infection in BALB/c mice.

Zhang AJ, Li C, To KK, Zhu HS, Lee AC, Li CG, Chan JF, Hung IF, Yuen KY.

Clin Vaccine Immunol. 2014 Apr;21(4):570-9. doi: 10.1128/CVI.00816-13. Epub 2014 Feb 12.


The relation of plasmacytoid dendritic cells (pDCs) and regulatory T-cells (Tregs) with HPV persistence in HIV-infected and HIV-uninfected women.

Strickler HD, Martinson J, Desai S, Xie X, Burk RD, Anastos K, Massad LS, Minkoff H, Xue X, D'Souza G, Levine AM, Colie C, Watts DH, Palefsky JM, Landay A.

Viral Immunol. 2014 Feb;27(1):20-5. doi: 10.1089/vim.2013.0097.


Trial watch: Dendritic cell-based interventions for cancer therapy.

Vacchelli E, Vitale I, Eggermont A, Fridman WH, Fučíková J, Cremer I, Galon J, Tartour E, Zitvogel L, Kroemer G, Galluzzi L.

Oncoimmunology. 2013 Oct 1;2(10):e25771. Epub 2013 Jul 29. Review.

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