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Items: 12


Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor.

Stehouwer JS, Birnbaum MS, Voll RJ, Owens MJ, Plott SJ, Bourke CH, Wassef MA, Kilts CD, Goodman MM.

Bioorg Med Chem. 2015 Aug 1;23(15):4286-302. doi: 10.1016/j.bmc.2015.06.036. Epub 2015 Jun 19.


Molecular imaging as a guide for the treatment of central nervous system disorders.

Kim E, Howes OD, Kapur S.

Dialogues Clin Neurosci. 2013 Sep;15(3):315-28. Review.


Beyond dopamine: glutamate as a target for future antipsychotics.

Sendt KV, Giaroli G, Tracy DK.

ISRN Pharmacol. 2012;2012:427267. doi: 10.5402/2012/427267. Epub 2012 Jul 5.


PET kinetics of radiolabeled antidepressant, [N-methyl-11C]mirtazapine, in the human brain.

Munk OL, Smith DF.

EJNMMI Res. 2011 Dec 15;1(1):36. doi: 10.1186/2191-219X-1-36.


D2 receptor overexpression in the striatum leads to a deficit in inhibitory transmission and dopamine sensitivity in mouse prefrontal cortex.

Li YC, Kellendonk C, Simpson EH, Kandel ER, Gao WJ.

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12107-12. doi: 10.1073/pnas.1109718108. Epub 2011 Jul 5. Erratum in: Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):4429.


How have developments in molecular imaging techniques furthered schizophrenia research?

Thompson JL, Urban N, Abi-Dargham A.

Imaging Med. 2009 Dec 1;1(2):135-153.


Fluorine-18 Radiolabeled PET Tracers for Imaging Monoamine Transporters: Dopamine, Serotonin, and Norepinephrine.

Stehouwer JS, Goodman MM.

PET Clin. 2009 Jan;4(1):101-28. doi: 10.1016/j.cpet.2009.05.006.


Brain serotonin transporter occupancy by oral sibutramine dosed to steady state: a PET study using (11)C-DASB in healthy humans.

Talbot PS, Bradley S, Clarke CP, Babalola KO, Philipp AW, Brown G, McMahon AW, Matthews JC.

Neuropsychopharmacology. 2010 Feb;35(3):741-51. doi: 10.1038/npp.2009.182. Epub 2009 Nov 4.


Synthesis, radiosynthesis, and biological evaluation of fluorine-18-labeled 2beta-carbo(fluoroalkoxy)-3beta-(3'-((Z)-2-haloethenyl)phenyl)nortropanes: candidate radioligands for in vivo imaging of the serotonin transporter with positron emission tomography.

Stehouwer JS, Jarkas N, Zeng F, Voll RJ, Williams L, Camp VM, Malveaux EJ, Votaw JR, Howell L, Owens MJ, Goodman MM.

J Med Chem. 2008 Dec 25;51(24):7788-99. doi: 10.1021/jm800781a.


Deconstructing psychosis with human brain imaging.

Gur RE, Keshavan MS, Lawrie SM.

Schizophr Bull. 2007 Jul;33(4):921-31. Epub 2007 Jun 4. Review.


Single-photon emission computed tomography in neurotherapeutics.

Devous MD Sr.

NeuroRx. 2005 Apr;2(2):237-49. Review.

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