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Items: 1 to 20 of 131


Bifurcated BACH2 control coordinates mantle cell lymphoma survival and dispersal during hypoxia.

Zhang H, Chen Z, Miranda RN, Medeiros LJ, McCarty N.

Blood. 2017 Aug 10;130(6):763-776. doi: 10.1182/blood-2017-02-767293. Epub 2017 Jun 7.


Cardiopulmonary phenotype associated with human PHD2 mutation.

Talbot NP, Smith TG, Balanos GM, Dorrington KL, Maxwell PH, Robbins PA.

Physiol Rep. 2017 Apr;5(7). pii: e13224. doi: 10.14814/phy2.13224.


Systems biology of oxygen homeostasis.

Samanta D, Prabhakar NR, Semenza GL.

Wiley Interdiscip Rev Syst Biol Med. 2017 Jul;9(4). doi: 10.1002/wsbm.1382. Epub 2017 Feb 21. Review.


Prospective study of thrombosis and thrombospondin-1 expression in Chuvash polycythemia.

Sergueeva A, Miasnikova G, Shah BN, Song J, Lisina E, Okhotin DJ, Nouraie M, Nekhai S, Ammosova T, Niu XM, Prchal JT, Zhang X, Gordeuk VR.

Haematologica. 2017 May;102(5):e166-e169. doi: 10.3324/haematol.2016.158170. Epub 2017 Jan 19. No abstract available.


Pulmonary vascular and ventricular dysfunction in the susceptible patient (2015 Grover Conference series).

Maron BA, Machado RF, Shimoda L.

Pulm Circ. 2016 Dec;6(4):426-438. doi: 10.1086/688315. Review.


Therapeutic inhibition of prolyl hydroxylase domain-containing enzymes in surgery: putative applications and challenges.

Harnoss JM, Strowitzki MJ, Radhakrishnan P, Platzer LK, Harnoss JC, Hank T, Cai J, Ulrich A, Schneider M.

Hypoxia (Auckl). 2015 Jan 30;3:1-14. eCollection 2015. Review.


The role of PHD2 mutations in the pathogenesis of erythrocytosis.

Gardie B, Percy MJ, Hoogewijs D, Chowdhury R, Bento C, Arsenault PR, Richard S, Almeida H, Ewing J, Lambert F, McMullin MF, Schofield CJ, Lee FS.

Hypoxia (Auckl). 2014 Jul 1;2:71-90. eCollection 2014. Review.


Gene panel sequencing improves the diagnostic work-up of patients with idiopathic erythrocytosis and identifies new mutations.

Camps C, Petousi N, Bento C, Cario H, Copley RR, McMullin MF, van Wijk R, Ratcliffe PJ, Robbins PA, Taylor JC; WGS500 Consortium.

Haematologica. 2016 Nov;101(11):1306-1318. Epub 2016 Sep 20.


Hypoxic Pulmonary Vasoconstriction: From Molecular Mechanisms to Medicine.

Dunham-Snary KJ, Wu D, Sykes EA, Thakrar A, Parlow LR, Mewburn JD, Parlow JL, Archer SL.

Chest. 2017 Jan;151(1):181-192. doi: 10.1016/j.chest.2016.09.001. Epub 2016 Sep 16. Review.


Identification of non-coding genetic variants in samples from hypoxemic respiratory disease patients that affect the transcriptional response to hypoxia.

Roche O, Deguiz ML, Tiana M, Galiana-Ribote C, Martinez-Alcazar D, Rey-Serra C, Ranz-Ribeiro B, Casitas R, Galera R, Fernández-Navarro I, Sánchez-Cuéllar S, Bernard V, Ancochea J, Wasserman WW, García-Rio F, Jimenez B, Del Peso L.

Nucleic Acids Res. 2016 Nov 2;44(19):9315-9330. Epub 2016 Sep 12.


Clinical Improvement with JAK2 Inhibition in Chuvash Polycythemia.

Zhou AW, Knoche EM, Engle EK, Ban-Hoefen M, Kaiwar C, Oh ST.

N Engl J Med. 2016 Aug 4;375(5):494-6. doi: 10.1056/NEJMc1600337. No abstract available.


The von Hippel-Lindau Chuvash mutation in mice alters cardiac substrate and high-energy phosphate metabolism.

Slingo M, Cole M, Carr C, Curtis MK, Dodd M, Giles L, Heather LC, Tyler D, Clarke K, Robbins PA.

Am J Physiol Heart Circ Physiol. 2016 Sep 1;311(3):H759-67. doi: 10.1152/ajpheart.00912.2015. Epub 2016 Jul 15.


The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 Is Essential for Efficient Hydroxylation of Hypoxia-Inducible Factor α.

Arsenault PR, Song D, Chung YJ, Khurana TS, Lee FS.

Mol Cell Biol. 2016 Aug 26;36(18):2328-43. doi: 10.1128/MCB.00090-16. Print 2016 Sep 15.


HIF2α Is an Essential Molecular Brake for Postprandial Hepatic Glucagon Response Independent of Insulin Signaling.

Ramakrishnan SK, Zhang H, Takahashi S, Centofanti B, Periyasamy S, Weisz K, Chen Z, Uhler MD, Rui L, Gonzalez FJ, Shah YM.

Cell Metab. 2016 Mar 8;23(3):505-16. doi: 10.1016/j.cmet.2016.01.004. Epub 2016 Feb 4.


Pathophysiology and treatment of pulmonary hypertension in sickle cell disease.

Gordeuk VR, Castro OL, Machado RF.

Blood. 2016 Feb 18;127(7):820-8. doi: 10.1182/blood-2015-08-618561. Epub 2016 Jan 12. Review.


Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis.

Kim Y, Nam HJ, Lee J, Park DY, Kim C, Yu YS, Kim D, Park SW, Bhin J, Hwang D, Lee H, Koh GY, Baek SH.

Nat Commun. 2016 Jan 13;7:10347. doi: 10.1038/ncomms10347.


The Dawning of a New Day in CKD Anemia Care?

Lenihan CR, Winkelmayer WC.

J Am Soc Nephrol. 2016 Apr;27(4):968-70. doi: 10.1681/ASN.2015091009. Epub 2015 Oct 22. No abstract available.


Hypoxia Inducible Factor Pathway and Physiological Adaptation: A Cell Survival Pathway?

Kumar H, Choi DK.

Mediators Inflamm. 2015;2015:584758. doi: 10.1155/2015/584758. Epub 2015 Sep 27. Review.


Targeting EPO and EPO receptor pathways in anemia and dysregulated erythropoiesis.

Rainville N, Jachimowicz E, Wojchowski DM.

Expert Opin Ther Targets. 2016;20(3):287-301. doi: 10.1517/14728222.2016.1090975. Epub 2015 Sep 30. Review.

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