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Emissive nanoparticles from pyridinium-substituted tetraphenylethylene salts: imaging and selective cytotoxicity towards cancer cells in vitro and in vivo by varying counter anions.

Huang Y, Zhang G, Hu F, Jin Y, Zhao R, Zhang D.

Chem Sci. 2016 Dec 1;7(12):7013-7019. doi: 10.1039/c6sc02395a. Epub 2016 Jul 18.


The plant defensin NaD1 induces tumor cell death via a non-apoptotic, membranolytic process.

Baxter AA, Poon IK, Hulett MD.

Cell Death Discov. 2017 Jan 23;3:16102. doi: 10.1038/cddiscovery.2016.102. eCollection 2017.


Annexin-directed β-glucuronidase for the targeted treatment of solid tumors.

Guillen KP, Ruben EA, Virani N, Harrison RG.

Protein Eng Des Sel. 2017 Feb;30(2):85-94. doi: 10.1093/protein/gzw063. Epub 2016 Dec 15.


Ligand Activation of TAM Family Receptors-Implications for Tumor Biology and Therapeutic Response.

Davra V, Kimani SG, Calianese D, Birge RB.

Cancers (Basel). 2016 Nov 29;8(12). pii: E107. Review.


Identification of the minimum pharmacophore of lipid-phosphatidylserine (PS) binding peptide-peptoid hybrid PPS1D1.

Singh J, Shukla SP, Desai TJ, Udugamasooriya DG.

Bioorg Med Chem. 2016 Sep 15;24(18):4470-7. doi: 10.1016/j.bmc.2016.07.045. Epub 2016 Jul 21.


Phosphatidylserine-targeted liposome for enhanced glioma-selective imaging.

Zhang L, Habib AA, Zhao D.

Oncotarget. 2016 Jun 21;7(25):38693-38706. doi: 10.18632/oncotarget.9584.


Detection of cancer cells using SapC-DOPS nanovesicles.

Davis HW, Hussain N, Qi X.

Mol Cancer. 2016 May 10;15(1):33. doi: 10.1186/s12943-016-0519-1. Review.


Identification of lipid-phosphatidylserine (PS) as the target of unbiasedly selected cancer specific peptide-peptoid hybrid PPS1.

Desai TJ, Toombs JE, Minna JD, Brekken RA, Udugamasooriya DG.

Oncotarget. 2016 May 24;7(21):30678-90. doi: 10.18632/oncotarget.8929.


The C-Terminal Acidic Region of Calreticulin Mediates Phosphatidylserine Binding and Apoptotic Cell Phagocytosis.

Wijeyesakere SJ, Bedi SK, Huynh D, Raghavan M.

J Immunol. 2016 May 1;196(9):3896-909. doi: 10.4049/jimmunol.1502122. Epub 2016 Apr 1.


Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer.

Birge RB, Boeltz S, Kumar S, Carlson J, Wanderley J, Calianese D, Barcinski M, Brekken RA, Huang X, Hutchins JT, Freimark B, Empig C, Mercer J, Schroit AJ, Schett G, Herrmann M.

Cell Death Differ. 2016 Jun;23(6):962-78. doi: 10.1038/cdd.2016.11. Epub 2016 Feb 26. Review.


Exposure of phosphatidylserine on the cell surface.

Nagata S, Suzuki J, Segawa K, Fujii T.

Cell Death Differ. 2016 Jun;23(6):952-61. doi: 10.1038/cdd.2016.7. Epub 2016 Feb 19. Review.


Advances and Challenges of Liposome Assisted Drug Delivery.

Sercombe L, Veerati T, Moheimani F, Wu SY, Sood AK, Hua S.

Front Pharmacol. 2015 Dec 1;6:286. doi: 10.3389/fphar.2015.00286. eCollection 2015. Review.


Tumor-specific targeting by Bavituximab, a phosphatidylserine-targeting monoclonal antibody with vascular targeting and immune modulating properties, in lung cancer xenografts.

Gerber DE, Hao G, Watkins L, Stafford JH, Anderson J, Holbein B, Öz OK, Mathews D, Thorpe PE, Hassan G, Kumar A, Brekken RA, Sun X.

Am J Nucl Med Mol Imaging. 2015 Oct 12;5(5):493-503. eCollection 2015.


Phosphatidylserine (PS) Is Exposed in Choroidal Neovascular Endothelium: PS-Targeting Antibodies Inhibit Choroidal Angiogenesis In Vivo and Ex Vivo.

Li T, Aredo B, Zhang K, Zhong X, Pulido JS, Wang S, He YG, Huang X, Brekken RA, Ufret-Vincenty RL.

Invest Ophthalmol Vis Sci. 2015 Nov;56(12):7137-45. doi: 10.1167/iovs.15-17302.


Hirsutellin A: A Paradigmatic Example of the Insecticidal Function of Fungal Ribotoxins.

Herrero-Galán E, García-Ortega L, Olombrada M, Lacadena J, Del Pozo ÁM, Gavilanes JG, Oñaderra M.

Insects. 2013 Jul 9;4(3):339-56. doi: 10.3390/insects4030339. Review.


The phospholipid code: a key component of dying cell recognition, tumor progression and host-microbe interactions.

Baxter AA, Hulett MD, Poon IK.

Cell Death Differ. 2015 Dec;22(12):1893-905. doi: 10.1038/cdd.2015.122. Epub 2015 Oct 9. Review.


In vitro Characterization of the Rapid Cytotoxicity of Anticancer Peptide HPRP-A2 through Membrane Destruction and Intracellular Mechanism against Gastric Cancer Cell Lines.

Zhao J, Hao X, Liu D, Huang Y, Chen Y.

PLoS One. 2015 Sep 30;10(9):e0139578. doi: 10.1371/journal.pone.0139578. eCollection 2015.


Update on ischemia-reperfusion injury in kidney transplantation: Pathogenesis and treatment.

Salvadori M, Rosso G, Bertoni E.

World J Transplant. 2015 Jun 24;5(2):52-67. doi: 10.5500/wjt.v5.i2.52. Review.


Nanotechnology-Based Drug Delivery Systems for Melanoma Antitumoral Therapy: A Review.

Rigon RB, Oyafuso MH, Fujimura AT, Gonçalez ML, do Prado AH, Gremião MP, Chorilli M.

Biomed Res Int. 2015;2015:841817. doi: 10.1155/2015/841817. Epub 2015 May 11. Review.

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