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Items: 1 to 20 of 57


Deletion of Type 2 Metabotropic Glutamate Receptor Decreases Sensitivity to Cocaine Reward in Rats.

Yang HJ, Zhang HY, Bi GH, He Y, Gao JT, Xi ZX.

Cell Rep. 2017 Jul 11;20(2):319-332. doi: 10.1016/j.celrep.2017.06.046.


Presynaptic G Protein-Coupled Receptors: Gatekeepers of Addiction?

Johnson KA, Lovinger DM.

Front Cell Neurosci. 2016 Nov 11;10:264. eCollection 2016. Review.


Methamphetamine Addiction Vulnerability: The Glutamate, the Bad, and the Ugly.

Szumlinski KK, Lominac KD, Campbell RR, Cohen M, Fultz EK, Brown CN, Miller BW, Quadir SG, Martin D, Thompson AB, von Jonquieres G, Klugmann M, Phillips TJ, Kippin TE.

Biol Psychiatry. 2017 Jun 1;81(11):959-970. doi: 10.1016/j.biopsych.2016.10.005. Epub 2016 Oct 13.


Chronic methamphetamine self-administration disrupts cortical control of cognition.

Bernheim A, See RE, Reichel CM.

Neurosci Biobehav Rev. 2016 Oct;69:36-48. doi: 10.1016/j.neubiorev.2016.07.020. Epub 2016 Jul 20. Review.


The individual and combined effects of phenmetrazine and mgluR2/3 agonist LY379268 on the motivation to self-administer cocaine.

Karkhanis AN, Beveridge TJ, Blough BE, Jones SR, Ferris MJ.

Drug Alcohol Depend. 2016 Sep 1;166:51-60. doi: 10.1016/j.drugalcdep.2016.06.020. Epub 2016 Jun 25.


Main path and byways: non-vesicular glutamate release by system xc(-) as an important modifier of glutamatergic neurotransmission.

Massie A, Boillée S, Hewett S, Knackstedt L, Lewerenz J.

J Neurochem. 2015 Dec;135(6):1062-79. doi: 10.1111/jnc.13348. Epub 2015 Sep 29. Review.


Opposing role for Egr3 in nucleus accumbens cell subtypes in cocaine action.

Chandra R, Francis TC, Konkalmatt P, Amgalan A, Gancarz AM, Dietz DM, Lobo MK.

J Neurosci. 2015 May 20;35(20):7927-37. doi: 10.1523/JNEUROSCI.0548-15.2015.


Effect of the Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor 2 AZD8529 on Incubation of Methamphetamine Craving After Prolonged Voluntary Abstinence in a Rat Model.

Caprioli D, Venniro M, Zeric T, Li X, Adhikary S, Madangopal R, Marchant NJ, Lucantonio F, Schoenbaum G, Bossert JM, Shaham Y.

Biol Psychiatry. 2015 Oct 1;78(7):463-73. doi: 10.1016/j.biopsych.2015.02.018. Epub 2015 Feb 23.


Design and synthesis of systemically active metabotropic glutamate subtype-2 and -3 (mGlu2/3) receptor positive allosteric modulators (PAMs): pharmacological characterization and assessment in a rat model of cocaine dependence.

Dhanya RP, Sheffler DJ, Dahl R, Davis M, Lee PS, Yang L, Nickols HH, Cho HP, Smith LH, D'Souza MS, Conn PJ, Der-Avakian A, Markou A, Cosford ND.

J Med Chem. 2014 May 22;57(10):4154-72. doi: 10.1021/jm5000563. Epub 2014 May 9.


Metabotropic glutamate receptor 3 is associated with heroin dependence but not depression or schizophrenia in a Chinese population.

Jia W, Zhang R, Wu B, Dai ZX, Zhu YS, Li PP, Zhu F.

PLoS One. 2014 Jan 31;9(1):e87247. doi: 10.1371/journal.pone.0087247. eCollection 2014.


Astrocytic dysfunction and addiction: consequences of impaired glutamate homeostasis.

Scofield MD, Kalivas PW.

Neuroscientist. 2014 Dec;20(6):610-22. doi: 10.1177/1073858413520347. Epub 2014 Feb 3. Review.


Decreased striatal dopamine in group II metabotropic glutamate receptor (mGlu2/mGlu3) double knockout mice.

Lane TA, Boerner T, Bannerman DM, Kew JN, Tunbridge EM, Sharp T, Harrison PJ.

BMC Neurosci. 2013 Sep 22;14:102. doi: 10.1186/1471-2202-14-102.


Low- and high-cocaine locomotor responding rats differ in reinstatement of cocaine seeking and striatal mGluR5 protein expression.

Simmons DL, Mandt BH, Ng CM, Richards TL, Yamamoto DJ, Zahniser NR, Allen RM.

Neuropharmacology. 2013 Dec;75:347-55. doi: 10.1016/j.neuropharm.2013.08.001. Epub 2013 Aug 22.


Imbalances in prefrontal cortex CC-Homer1 versus CC-Homer2 expression promote cocaine preference.

Ary AW, Lominac KD, Wroten MG, Williams AR, Campbell RR, Ben-Shahar O, von Jonquieres G, Klugmann M, Szumlinski KK.

J Neurosci. 2013 May 8;33(19):8101-13. doi: 10.1523/JNEUROSCI.1727-12.2013.


Rapid, transient synaptic plasticity in addiction.

Gipson CD, Kupchik YM, Kalivas PW.

Neuropharmacology. 2014 Jan;76 Pt B:276-86. doi: 10.1016/j.neuropharm.2013.04.032. Epub 2013 Apr 29. Review.


Orally active metabotropic glutamate subtype 2 receptor positive allosteric modulators: structure-activity relationships and assessment in a rat model of nicotine dependence.

Sidique S, Dhanya RP, Sheffler DJ, Nickols HH, Yang L, Dahl R, Mangravita-Novo A, Smith LH, D'Souza MS, Semenova S, Conn PJ, Markou A, Cosford ND.

J Med Chem. 2012 Nov 26;55(22):9434-45. doi: 10.1021/jm3005306. Epub 2012 Oct 23.


mGluR-Dependent Synaptic Plasticity in Drug-Seeking.

Bellone C, Mameli M.

Front Pharmacol. 2012 Aug 27;3:159. doi: 10.3389/fphar.2012.00159. eCollection 2012.


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