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Grb7 Protein Stability Modulated by Pin1 in Association with Cell Cycle Progression.

Tai YL, Tung LH, Lin YC, Lu PJ, Chu PY, Wang MY, Huang WP, Chen KC, Lee H, Shen TL.

PLoS One. 2016 Sep 22;11(9):e0163617. doi: 10.1371/journal.pone.0163617.


Pin1 is required for sustained B cell proliferation upon oncogenic activation of Myc.

D'Artista L, Bisso A, Piontini A, Doni M, Verrecchia A, Kress TR, Morelli MJ, Del Sal G, Amati B, Campaner S.

Oncotarget. 2016 Apr 19;7(16):21786-98. doi: 10.18632/oncotarget.7846.


Peptidyl Prolyl Isomerase PIN1 Directly Binds to and Stabilizes Hypoxia-Inducible Factor-1α.

Han HJ, Kwon N, Choi MA, Jung KO, Piao JY, Ngo HK, Kim SJ, Kim DH, Chung JK, Cha YN, Youn H, Choi BY, Min SH, Surh YJ.

PLoS One. 2016 Jan 19;11(1):e0147038. doi: 10.1371/journal.pone.0147038. Erratum in: PLoS One. 2016;11(3):e0151517.


Negative Regulation of Peptidyl-Prolyl Isomerase Activity by Interdomain Contact in Human Pin1.

Wang X, Mahoney BJ, Zhang M, Zintsmaster JS, Peng JW.

Structure. 2015 Dec 1;23(12):2224-33. doi: 10.1016/j.str.2015.08.019.


Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis.

Follis AV, Llambi F, Merritt P, Chipuk JE, Green DR, Kriwacki RW.

Mol Cell. 2015 Aug 20;59(4):677-84. doi: 10.1016/j.molcel.2015.06.029.


Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients.

Osman AA, Neskey DM, Katsonis P, Patel AA, Ward AM, Hsu TK, Hicks SC, McDonald TO, Ow TJ, Alves MO, Pickering CR, Skinner HD, Zhao M, Sturgis EM, Kies MS, El-Naggar A, Perrone F, Licitra L, Bossi P, Kimmel M, Frederick MJ, Lichtarge O, Myers JN.

Cancer Res. 2015 Apr 1;75(7):1205-15. doi: 10.1158/0008-5472.CAN-14-2729.


KSHV reactivation and novel implications of protein isomerization on lytic switch control.

Guito J, Lukac DM.

Viruses. 2015 Jan 12;7(1):72-109. doi: 10.3390/v7010072. Review.


Pin1 dysregulation helps to explain the inverse association between cancer and Alzheimer's disease.

Driver JA, Zhou XZ, Lu KP.

Biochim Biophys Acta. 2015 Oct;1850(10):2069-76. doi: 10.1016/j.bbagen.2014.12.025. Review.


Prolyl isomerase Pin1 in cancer.

Lu Z, Hunter T.

Cell Res. 2014 Sep;24(9):1033-49. doi: 10.1038/cr.2014.109. Review.


ShaPINg Cell Fate Upon DNA Damage: Role of Pin1 Isomerase in DNA Damage-Induced Cell Death and Repair.

Polonio-Vallon T, Krüger D, Hofmann TG.

Front Oncol. 2014 Jun 16;4:148. doi: 10.3389/fonc.2014.00148. Review.


Illuminating p53 function in cancer with genetically engineered mouse models.

Garcia PB, Attardi LD.

Semin Cell Dev Biol. 2014 Mar;27:74-85. doi: 10.1016/j.semcdb.2013.12.014. Review.


Differential regulation of cellular senescence and differentiation by prolyl isomerase Pin1 in cardiac progenitor cells.

Toko H, Hariharan N, Konstandin MH, Ormachea L, McGregor M, Gude NA, Sundararaman B, Joyo E, Joyo AY, Collins B, Din S, Mohsin S, Uchida T, Sussman MA.

J Biol Chem. 2014 Feb 28;289(9):5348-56. doi: 10.1074/jbc.M113.526442.


Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast.

Rustighi A, Zannini A, Tiberi L, Sommaggio R, Piazza S, Sorrentino G, Nuzzo S, Tuscano A, Eterno V, Benvenuti F, Santarpia L, Aifantis I, Rosato A, Bicciato S, Zambelli A, Del Sal G.

EMBO Mol Med. 2014 Jan;6(1):99-119. doi: 10.1002/emmm.201302909. Erratum in: EMBO Mol Med. 2014 May;6(5):702.


Expression of peptidyl-prolyl isomerase PIN1 and its role in the pathogenesis of extrahepatic cholangiocarcinoma.

Jamiyandorj U, Bae JS, Noh SJ, Jachin S, Choi JE, Jang KY, Chung MJ, Kang MJ, Lee DG, Moon WS.

Oncol Lett. 2013 Nov;6(5):1421-1426.


The cellular peptidyl-prolyl cis/trans isomerase Pin1 regulates reactivation of Kaposi's sarcoma-associated herpesvirus from latency.

Guito J, Gavina A, Palmeri D, Lukac DM.

J Virol. 2014 Jan;88(1):547-58. doi: 10.1128/JVI.02877-13.


Autophosphorylation and Pin1 binding coordinate DNA damage-induced HIPK2 activation and cell death.

Bitomsky N, Conrad E, Moritz C, Polonio-Vallon T, Sombroek D, Schultheiss K, Glas C, Greiner V, Herbel C, Mantovani F, del Sal G, Peri F, Hofmann TG.

Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):E4203-12. doi: 10.1073/pnas.1310001110.


The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease.

Ghosh A, Saminathan H, Kanthasamy A, Anantharam V, Jin H, Sondarva G, Harischandra DS, Qian Z, Rana A, Kanthasamy AG.

J Biol Chem. 2013 Jul 26;288(30):21955-71. doi: 10.1074/jbc.M112.444224.


Signaling pathways that control mRNA turnover.

Thapar R, Denmon AP.

Cell Signal. 2013 Aug;25(8):1699-710. doi: 10.1016/j.cellsig.2013.03.026. Review.


Pin1 modulates ERα levels in breast cancer through inhibition of phosphorylation-dependent ubiquitination and degradation.

Rajbhandari P, Schalper KA, Solodin NM, Ellison-Zelski SJ, Ping Lu K, Rimm DL, Alarid ET.

Oncogene. 2014 Mar 13;33(11):1438-47. doi: 10.1038/onc.2013.78.

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