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Recent Progress in Research on the Pathogenesis of Pulmonary Thromboembolism: An Old Story with New Perspectives.

Yan C, Wang X, Su H, Ying K.

Biomed Res Int. 2017;2017:6516791. doi: 10.1155/2017/6516791. Epub 2017 Apr 6. Review.


The Role of Heterotypic DENV-specific CD8+T Lymphocytes in an Immunocompetent Mouse Model of Secondary Dengue Virus Infection.

Talarico LB, Batalle JP, Byrne AB, Brahamian JM, Ferretti A, García AG, Mauri A, Simonetto C, Hijano DR, Lawrence A, Acosta PL, Caballero MT, Paredes Rojas Y, Ibañez LI, Melendi GA, Rey FA, Damonte EB, Harris E, Polack FP.

EBioMedicine. 2017 Jun;20:202-216. doi: 10.1016/j.ebiom.2017.04.033. Epub 2017 Apr 27.


RGS10 Negatively Regulates Platelet Activation and Thrombogenesis.

Hensch NR, Karim ZA, Druey KM, Tansey MG, Khasawneh FT.

PLoS One. 2016 Nov 9;11(11):e0165984. doi: 10.1371/journal.pone.0165984. eCollection 2016.


Humanizing the Protease-Activated Receptor (PAR) Expression Profile in Mouse Platelets by Knocking PAR1 into the Par3 Locus Reveals PAR1 Expression Is Not Tolerated in Mouse Platelets.

French SL, Paramitha AC, Moon MJ, Dickins RA, Hamilton JR.

PLoS One. 2016 Oct 27;11(10):e0165565. doi: 10.1371/journal.pone.0165565. eCollection 2016.


The adaptor protein Disabled-2: new insights into platelet biology and integrin signaling.

Tsai HJ, Tseng CP.

Thromb J. 2016 Oct 4;14(Suppl 1):28. eCollection 2016. Review.


Protease-activated receptor 4: from structure to function and back again.

French SL, Hamilton JR.

Br J Pharmacol. 2016 Oct;173(20):2952-65. doi: 10.1111/bph.13455. Epub 2016 Mar 10. Review.


Evolution of the protease-activated receptor family in vertebrates.

Jin M, Yang HW, Tao AL, Wei JF.

Int J Mol Med. 2016 Mar;37(3):593-602. doi: 10.3892/ijmm.2016.2464. Epub 2016 Jan 22.


Non-invasive imaging and cellular tracking of pulmonary emboli by near-infrared fluorescence and positron-emission tomography.

Page MJ, Lourenço AL, David T, LeBeau AM, Cattaruzza F, Castro HC, VanBrocklin HF, Coughlin SR, Craik CS.

Nat Commun. 2015 Oct 1;6:8448. doi: 10.1038/ncomms9448.


The polyphosphate-factor XII pathway drives coagulation in prostate cancer-associated thrombosis.

Nickel KF, Ronquist G, Langer F, Labberton L, Fuchs TA, Bokemeyer C, Sauter G, Graefen M, Mackman N, Stavrou EX, Ronquist G, Renné T.

Blood. 2015 Sep 10;126(11):1379-89. doi: 10.1182/blood-2015-01-622811. Epub 2015 Jul 7.


A balance between TFPI and thrombin-mediated platelet activation is required for murine embryonic development.

Ellery PE, Maroney SA, Cooley BC, Luyendyk JP, Zogg M, Weiler H, Mast AE.

Blood. 2015 Jun 25;125(26):4078-84. doi: 10.1182/blood-2015-03-633958. Epub 2015 May 7.


Redundancy and interaction of thrombin- and collagen-mediated platelet activation in tail bleeding and carotid thrombosis in mice.

Bynagari-Settipalli YS, Cornelissen I, Palmer D, Duong D, Concengco C, Ware J, Coughlin SR.

Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2563-9. doi: 10.1161/ATVBAHA.114.304244. Epub 2014 Oct 2.


Disabled-2 is required for efficient hemostasis and platelet activation by thrombin in mice.

Tsai HJ, Huang CL, Chang YW, Huang DY, Lin CC, Cooper JA, Cheng JC, Tseng CP.

Arterioscler Thromb Vasc Biol. 2014 Nov;34(11):2404-12. doi: 10.1161/ATVBAHA.114.302602. Epub 2014 Sep 11.


Disease detection by ultrasensitive quantification of microdosed synthetic urinary biomarkers.

Warren AD, Gaylord ST, Ngan KC, Dumont Milutinovic M, Kwong GA, Bhatia SN, Walt DR.

J Am Chem Soc. 2014 Oct 1;136(39):13709-14. doi: 10.1021/ja505676h. Epub 2014 Sep 23.


Self-titrating anticoagulant nanocomplexes that restore homeostatic regulation of the coagulation cascade.

Lin KY, Lo JH, Consul N, Kwong GA, Bhatia SN.

ACS Nano. 2014 Sep 23;8(9):8776-85. doi: 10.1021/nn501129q. Epub 2014 Aug 19.


Nanoparticles that sense thrombin activity as synthetic urinary biomarkers of thrombosis.

Lin KY, Kwong GA, Warren AD, Wood DK, Bhatia SN.

ACS Nano. 2013 Oct 22;7(10):9001-9. doi: 10.1021/nn403550c. Epub 2013 Sep 12.


Calcium mobilization and protein kinase C activation downstream of protease activated receptor 4 (PAR4) is negatively regulated by PAR3 in mouse platelets.

Arachiche A, de la Fuente M, Nieman MT.

PLoS One. 2013;8(2):e55740. doi: 10.1371/journal.pone.0055740. Epub 2013 Feb 6. Erratum in: PLoS One. 2013;8(12). doi:10.1371/annotation/0956857d-ecf5-4fb7-a834-131915a38a6a.


Antibody SPC-54 provides acute in vivo blockage of the murine protein C system.

Burnier L, Fernández JA, Griffin JH.

Blood Cells Mol Dis. 2013 Apr;50(4):252-8. doi: 10.1016/j.bcmd.2013.01.002. Epub 2013 Feb 4.


Safety and efficacy of targeting platelet proteinase-activated receptors in combination with existing anti-platelet drugs as antithrombotics in mice.

Lee H, Sturgeon SA, Mountford JK, Jackson SP, Hamilton JR.

Br J Pharmacol. 2012 Aug;166(7):2188-97. doi: 10.1111/j.1476-5381.2012.01944.x.


JAM-A protects from thrombosis by suppressing integrin αIIbβ3-dependent outside-in signaling in platelets.

Naik MU, Stalker TJ, Brass LF, Naik UP.

Blood. 2012 Apr 5;119(14):3352-60. doi: 10.1182/blood-2011-12-397398. Epub 2012 Jan 23.


Thrombotic distal middle cerebral artery occlusion produced by topical FeCl(3) application: a novel model suitable for intravital microscopy and thrombolysis studies.

Karatas H, Erdener SE, Gursoy-Ozdemir Y, Gurer G, Soylemezoglu F, Dunn AK, Dalkara T.

J Cereb Blood Flow Metab. 2011 Jun;31(6):1452-60. doi: 10.1038/jcbfm.2011.8. Epub 2011 Feb 16.

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