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Exploiting Cell Death Pathways for Inducible Cell Elimination to Modulate Graft-versus-Host-Disease.

Falcon C, Al-Obaidi M, Di Stasi A.

Biomedicines. 2017 Jun 14;5(2). pii: E30. doi: 10.3390/biomedicines5020030. Review.


Restoring TRAIL Induced Apoptosis Using Naturopathy. Hercules Joins Hand with Nature to Triumph Over Lernaean Hydra.

Farooqi AA, Gadaleta CD, Ranieri G, Fayyaz S, Marech I.

Curr Genomics. 2017 Feb;18(1):27-38. doi: 10.2174/1389202917666160803150023. Review.


Caspase-8: regulating life and death.

Tummers B, Green DR.

Immunol Rev. 2017 May;277(1):76-89. doi: 10.1111/imr.12541. Review.


Caspase-10 Negatively Regulates Caspase-8-Mediated Cell Death, Switching the Response to CD95L in Favor of NF-κB Activation and Cell Survival.

Horn S, Hughes MA, Schilling R, Sticht C, Tenev T, Ploesser M, Meier P, Sprick MR, MacFarlane M, Leverkus M.

Cell Rep. 2017 Apr 25;19(4):785-797. doi: 10.1016/j.celrep.2017.04.010.


Exogenous expression of SAMHD1 inhibits proliferation and induces apoptosis in cutaneous T-cell lymphoma-derived HuT78 cells.

Kodigepalli KM, Li M, Liu SL, Wu L.

Cell Cycle. 2017 Jan 17;16(2):179-188. doi: 10.1080/15384101.2016.1261226. Epub 2016 Dec 8.


The contribution of the programmed cell death machinery in innate immune cells to lupus nephritis.

Tsai F, Perlman H, Cuda CM.

Clin Immunol. 2016 Oct 22. pii: S1521-6616(16)30517-4. doi: 10.1016/j.clim.2016.10.007. [Epub ahead of print]


Simultaneous induction of apoptosis and necroptosis by Tanshinone IIA in human hepatocellular carcinoma HepG2 cells.

Lin CY, Chang TW, Hsieh WH, Hung MC, Lin IH, Lai SC, Tzeng YJ.

Cell Death Discov. 2016 Oct 3;2:16065. eCollection 2016.


The inflammatory role of phagocyte apoptotic pathways in rheumatic diseases.

Cuda CM, Pope RM, Perlman H.

Nat Rev Rheumatol. 2016 Aug 23;12(9):543-58. doi: 10.1038/nrrheum.2016.132. Review.


Necroptosis of Dendritic Cells Promotes Activation of γδ T Cells.

Collins CC, Bashant K, Erikson C, Thwe PM, Fortner KA, Wang H, Morita CT, Budd RC.

J Innate Immun. 2016;8(5):479-92. doi: 10.1159/000446498. Epub 2016 Jul 19.


Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate.

Hughes MA, Powley IR, Jukes-Jones R, Horn S, Feoktistova M, Fairall L, Schwabe JW, Leverkus M, Cain K, MacFarlane M.

Mol Cell. 2016 Mar 17;61(6):834-49. doi: 10.1016/j.molcel.2016.02.023.


Onto better TRAILs for cancer treatment.

de Miguel D, Lemke J, Anel A, Walczak H, Martinez-Lostao L.

Cell Death Differ. 2016 May;23(5):733-47. doi: 10.1038/cdd.2015.174. Epub 2016 Mar 4. Review.


Balance between short and long isoforms of cFLIP regulates Fas-mediated apoptosis in vivo.

Ram DR, Ilyukha V, Volkova T, Buzdin A, Tai A, Smirnova I, Poltorak A.

Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1606-11. doi: 10.1073/pnas.1517562113. Epub 2016 Jan 21.


FLIP the Switch: Regulation of Apoptosis and Necroptosis by cFLIP.

Tsuchiya Y, Nakabayashi O, Nakano H.

Int J Mol Sci. 2015 Dec 18;16(12):30321-41. doi: 10.3390/ijms161226232. Review.


Marine Drugs Regulating Apoptosis Induced by Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL).

Elmallah MI, Micheau O.

Mar Drugs. 2015 Nov 13;13(11):6884-909. doi: 10.3390/md13116884. Review.


Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis.

Hwang HS, Kim HA.

Int J Mol Sci. 2015 Oct 30;16(11):26035-54. doi: 10.3390/ijms161125943. Review.


Molecular architecture of the DED chains at the DISC: regulation of procaspase-8 activation by short DED proteins c-FLIP and procaspase-8 prodomain.

Schleich K, Buchbinder JH, Pietkiewicz S, Kähne T, Warnken U, Öztürk S, Schnölzer M, Naumann M, Krammer PH, Lavrik IN.

Cell Death Differ. 2016 Apr;23(4):681-94. doi: 10.1038/cdd.2015.137. Epub 2015 Oct 23.


S-Nitrosylation in TNF superfamily signaling pathway: Implication in cancer.

Plenchette S, Romagny S, Laurens V, Bettaieb A.

Redox Biol. 2015 Dec;6:507-15. doi: 10.1016/j.redox.2015.08.019. Epub 2015 Sep 8. Review.


Ubiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of Homeostasis.

Meier P, Morris O, Broemer M.

Curr Top Dev Biol. 2015;114:209-39. doi: 10.1016/bs.ctdb.2015.07.015. Epub 2015 Sep 11. Review.


A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death.

Bucur O, Gaidos G, Yatawara A, Pennarun B, Rupasinghe C, Roux J, Andrei S, Guo B, Panaitiu A, Pellegrini M, Mierke DF, Khosravi-Far R.

Sci Rep. 2015 May 11;5:9893. doi: 10.1038/srep09893.


Surviving apoptosis: life-death signaling in single cells.

Flusberg DA, Sorger PK.

Trends Cell Biol. 2015 Aug;25(8):446-58. doi: 10.1016/j.tcb.2015.03.003. Epub 2015 Apr 25. Review.

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