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The Toll-Like Receptor 4 Antagonist Eritoran Protects Mice from Lethal Filovirus Challenge.

Younan P, Ramanathan P, Graber J, Gusovsky F, Bukreyev A.

MBio. 2017 Apr 25;8(2). pii: e00226-17. doi: 10.1128/mBio.00226-17.


Anti-myeloperoxidase antibodies attenuate the monocyte response to LPS and shape macrophage development.

Popat RJ, Hakki S, Thakker A, Coughlan AM, Watson J, Little MA, Spickett CM, Lavender P, Afzali B, Kemper C, Robson MG.

JCI Insight. 2017 Jan 26;2(2):e87379. doi: 10.1172/jci.insight.87379.


Context-Dependent Role of Oxidized Lipids and Lipoproteins in Inflammation.

Miller YI, Shyy JY.

Trends Endocrinol Metab. 2017 Feb;28(2):143-152. doi: 10.1016/j.tem.2016.11.002. Epub 2016 Dec 5. Review.


Oxidized Phospholipid OxPAPC Activates TRPA1 and Contributes to Chronic Inflammatory Pain in Mice.

Liu B, Tai Y, Caceres AI, Achanta S, Balakrishna S, Shao X, Fang J, Jordt SE.

PLoS One. 2016 Nov 3;11(11):e0165200. doi: 10.1371/journal.pone.0165200. eCollection 2016.


DAMPs, MAMPs, and NAMPs in plant innate immunity.

Choi HW, Klessig DF.

BMC Plant Biol. 2016 Oct 26;16(1):232. Review.


Role of IQGAP1 in endothelial barrier enhancement caused by OxPAPC.

Tian Y, Tian X, Gawlak G, Sarich N, Sacks DB, Birukova AA, Birukov KG.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 26:ajplung.00095.2016. doi: 10.1152/ajplung.00095.2016. [Epub ahead of print]


Phospholipid Ozonation Products Activate the 5-Lipoxygenase Pathway in Macrophages.

Zemski Berry KA, Murphy RC.

Chem Res Toxicol. 2016 Aug 15;29(8):1355-64. doi: 10.1021/acs.chemrestox.6b00193. Epub 2016 Aug 3.


Role for phospholipid acyl chains and cholesterol in pulmonary infections and inflammation.

Shaikh SR, Fessler MB, Gowdy KM.

J Leukoc Biol. 2016 Nov;100(5):985-997. Epub 2016 Jun 10. Review.


An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells.

Zanoni I, Tan Y, Di Gioia M, Broggi A, Ruan J, Shi J, Donado CA, Shao F, Wu H, Springstead JR, Kagan JC.

Science. 2016 Jun 3;352(6290):1232-6. doi: 10.1126/science.aaf3036. Epub 2016 Apr 21.


Lipopolysaccharide Cross-Tolerance Delays Platelet-Activating Factor-Induced Sudden Death in Swiss Albino Mice: Involvement of Cyclooxygenase in Cross-Tolerance.

Jacob SP, Lakshmikanth CL, Chaithra VH, Kumari TR, Chen CH, McIntyre TM, Marathe GK.

PLoS One. 2016 Apr 11;11(4):e0153282. doi: 10.1371/journal.pone.0153282. eCollection 2016.


The Role of Platelet-Activating Factor in Chronic Inflammation, Immune Activation, and Comorbidities Associated with HIV Infection.

Kelesidis T, Papakonstantinou V, Detopoulou P, Fragopoulou E, Chini M, Lazanas MC, Antonopoulou S.

AIDS Rev. 2015 Oct-Dec;17(4):191-201. Review.


4-Hydroxy-nonenal-A Bioactive Lipid Peroxidation Product.

Schaur RJ, Siems W, Bresgen N, Eckl PM.

Biomolecules. 2015 Sep 30;5(4):2247-337. doi: 10.3390/biom5042247. Review.


Phospholipid oxidation generates potent anti-inflammatory lipid mediators that mimic structurally related pro-resolving eicosanoids by activating Nrf2.

Bretscher P, Egger J, Shamshiev A, Trötzmüller M, Köfeler H, Carreira EM, Kopf M, Freigang S.

EMBO Mol Med. 2015 May;7(5):593-607. doi: 10.15252/emmm.201404702.


Innate immune pattern recognition: a cell biological perspective.

Brubaker SW, Bonham KS, Zanoni I, Kagan JC.

Annu Rev Immunol. 2015;33:257-90. doi: 10.1146/annurev-immunol-032414-112240. Epub 2015 Jan 2. Review.


Oxidized phospholipids protect against lung injury and endothelial barrier dysfunction caused by heat-inactivated Staphylococcus aureus.

Meliton AY, Meng F, Tian Y, Sarich N, Mutlu GM, Birukova AA, Birukov KG.

Am J Physiol Lung Cell Mol Physiol. 2015 Mar 15;308(6):L550-62. doi: 10.1152/ajplung.00248.2014. Epub 2015 Jan 9.


Lp-PLA2 Inhibitors for the Reduction of Cardiovascular Events.

Steen DL, O'Donoghue ML.

Cardiol Ther. 2013 Dec;2(2):125-34. doi: 10.1007/s40119-013-0022-3. Epub 2013 Sep 25.


To hydrolyze or not to hydrolyze: the dilemma of platelet-activating factor acetylhydrolase.

Marathe GK, Pandit C, Lakshmikanth CL, Chaithra VH, Jacob SP, D'Souza CJ.

J Lipid Res. 2014 Sep;55(9):1847-54. doi: 10.1194/jlr.R045492. Epub 2014 May 23. Review.


GRP78 is a novel receptor initiating a vascular barrier protective response to oxidized phospholipids.

Birukova AA, Singleton PA, Gawlak G, Tian X, Mirzapoiazova T, Mambetsariev B, Dubrovskyi O, Oskolkova OV, Bochkov VN, Birukov KG.

Mol Biol Cell. 2014 Jul 1;25(13):2006-16. doi: 10.1091/mbc.E13-12-0743. Epub 2014 May 14.


Admission lipoprotein-associated phospholipase A2 activity is not associated with long-term clinical outcomes after ST-segment elevation myocardial infarction.

Woudstra P, Damman P, Kuijt WJ, Kikkert WJ, Grundeken MJ, van Brussel PM, Stroobants AK, van Straalen JP, Fischer JC, Koch KT, Henriques JP, Piek JJ, Tijssen JG, de Winter RJ.

PLoS One. 2014 May 1;9(5):e96251. doi: 10.1371/journal.pone.0096251. eCollection 2014.

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