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Items: 1 to 20 of 61

1.

Nonhomologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in Schizosaccharomyces pombe.

Li Y, Wang J, Zhou G, Lajeunesse M, Le N, Stawicki BN, Corcino YL, Berkner KL, Runge KW.

Genetics. 2017 May;206(1):481-496. doi: 10.1534/genetics.117.200972. Epub 2017 Mar 14.

PMID:
28292918
2.

Distinct Brca1 Mutations Differentially Reduce Hematopoietic Stem Cell Function.

Mgbemena VE, Signer RAJ, Wijayatunge R, Laxson T, Morrison SJ, Ross TS.

Cell Rep. 2017 Jan 24;18(4):947-960. doi: 10.1016/j.celrep.2016.12.075.

3.

Rejuvenation of aged hematopoietic stem cells.

Guidi N, Geiger H.

Semin Hematol. 2017 Jan;54(1):51-55. doi: 10.1053/j.seminhematol.2016.10.005. Epub 2016 Oct 24. Review.

PMID:
28088989
4.

Aging of hematopoietic stem cells: DNA damage and mutations?

Moehrle BM, Geiger H.

Exp Hematol. 2016 Oct;44(10):895-901. doi: 10.1016/j.exphem.2016.06.253. Epub 2016 Jul 8. Review.

5.

DNA Damage Response in Hematopoietic Stem Cell Ageing.

Li T, Zhou ZW, Ju Z, Wang ZQ.

Genomics Proteomics Bioinformatics. 2016 Jun;14(3):147-154. doi: 10.1016/j.gpb.2016.04.002. Epub 2016 May 21. Review.

6.

Generation of a novel, multi-stage, progressive, and transplantable model of plasma cell neoplasms.

Asai T, Hatlen MA, Lossos C, Ndiaye-Lobry D, Deblasio A, Murata K, Fleisher M, Cortizas EM, Verdun RE, Petrini J, Nimer SD.

Sci Rep. 2016 Mar 10;6:22760. doi: 10.1038/srep22760.

7.

Fancb deficiency impairs hematopoietic stem cell function.

Du W, Amarachintha S, Erden O, Wilson A, Meetei AR, Andreassen PR, Namekawa SH, Pang Q.

Sci Rep. 2015 Dec 11;5:18127. doi: 10.1038/srep18127.

8.

Fine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at work.

Citterio E.

Front Genet. 2015 Sep 8;6:282. doi: 10.3389/fgene.2015.00282. eCollection 2015. Review.

9.

Concise review: hematopoietic stem cell aging and the prospects for rejuvenation.

Wahlestedt M, Pronk CJ, Bryder D.

Stem Cells Transl Med. 2015 Feb;4(2):186-94. doi: 10.5966/sctm.2014-0132. Epub 2014 Dec 29. Review.

10.

Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study.

Damiola F, Pertesi M, Oliver J, Le Calvez-Kelm F, Voegele C, Young EL, Robinot N, Forey N, Durand G, Vallée MP, Tao K, Roane TC, Williams GJ, Hopper JL, Southey MC, Andrulis IL, John EM, Goldgar DE, Lesueur F, Tavtigian SV.

Breast Cancer Res. 2014 Jun 3;16(3):R58. doi: 10.1186/bcr3669.

11.

The Rad50 hook domain regulates DNA damage signaling and tumorigenesis.

Roset R, Inagaki A, Hohl M, Brenet F, Lafrance-Vanasse J, Lange J, Scandura JM, Tainer JA, Keeney S, Petrini JH.

Genes Dev. 2014 Mar 1;28(5):451-62. doi: 10.1101/gad.236745.113. Epub 2014 Feb 14.

12.

Myelodysplastic syndrome: an inability to appropriately respond to damaged DNA?

Zhou T, Hasty P, Walter CA, Bishop AJ, Scott LM, Rebel VI.

Exp Hematol. 2013 Aug;41(8):665-74. doi: 10.1016/j.exphem.2013.04.008. Epub 2013 Apr 30. Review.

13.

Stem cells and aging: a chicken-or-the-egg issue?

Smith JA, Daniel R.

Aging Dis. 2012 Jun;3(3):260-8. Epub 2012 Feb 13.

14.

A sensitive and quantitative polymerase chain reaction-based cell free in vitro non-homologous end joining assay for hematopoietic stem cells.

Shao L, Feng W, Lee KJ, Chen BP, Zhou D.

PLoS One. 2012;7(3):e33499. doi: 10.1371/journal.pone.0033499. Epub 2012 Mar 20.

15.
16.

The p53 tumor suppressor protein regulates hematopoietic stem cell fate.

Asai T, Liu Y, Bae N, Nimer SD.

J Cell Physiol. 2011 Sep;226(9):2215-21. doi: 10.1002/jcp.22561. Review.

17.

Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer.

El Ghamrasni S, Pamidi A, Halaby MJ, Bohgaki M, Cardoso R, Li L, Venkatesan S, Sethu S, Hirao A, Mak TW, Hande MP, Hakem A, Hakem R.

PLoS Genet. 2011 May;7(5):e1001385. doi: 10.1371/journal.pgen.1001385. Epub 2011 May 19.

18.

Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair.

Zhang S, Yajima H, Huynh H, Zheng J, Callen E, Chen HT, Wong N, Bunting S, Lin YF, Li M, Lee KJ, Story M, Gapud E, Sleckman BP, Nussenzweig A, Zhang CC, Chen DJ, Chen BP.

J Cell Biol. 2011 Apr 18;193(2):295-305. doi: 10.1083/jcb.201009074. Epub 2011 Apr 11.

19.

Aberrant chromosome morphology in human cells defective for Holliday junction resolution.

Wechsler T, Newman S, West SC.

Nature. 2011 Mar 31;471(7340):642-6. doi: 10.1038/nature09790. Epub 2011 Mar 13.

20.

The MRE11 complex: starting from the ends.

Stracker TH, Petrini JH.

Nat Rev Mol Cell Biol. 2011 Feb;12(2):90-103. doi: 10.1038/nrm3047. Review.

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