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Items: 1 to 20 of 43

1.

Protein Kinases and Parkinson's Disease.

Mehdi SJ, Rosas-Hernandez H, Cuevas E, Lantz SM, Barger SW, Sarkar S, Paule MG, Ali SF, Imam SZ.

Int J Mol Sci. 2016 Sep 20;17(9). pii: E1585. Review.

2.

Dephosphorylation and mitochondrial translocation of cofilin sensitizes human leukemia cells to cerulenin-induced apoptosis via the ROCK1/Akt/JNK signaling pathway.

Zhang Y, Fu R, Liu Y, Li J, Zhang H, Hu X, Chen Y, Liu X, Li Y, Li P, Liu E, Gao N.

Oncotarget. 2016 Apr 12;7(15):20655-68. doi: 10.18632/oncotarget.7994.

3.

Context Specificity of Stress-activated Mitogen-activated Protein (MAP) Kinase Signaling: The Story as Told by Caenorhabditis elegans.

Andrusiak MG, Jin Y.

J Biol Chem. 2016 Apr 8;291(15):7796-804. doi: 10.1074/jbc.R115.711101. Epub 2016 Feb 23. Review.

4.

All Akt isoforms (Akt1, Akt2, Akt3) are involved in normal hearing, but only Akt2 and Akt3 are involved in auditory hair cell survival in the mammalian inner ear.

Brand Y, Levano S, Radojevic V, Naldi AM, Setz C, Ryan AF, Pak K, Hemmings BA, Bodmer D.

PLoS One. 2015 Mar 26;10(3):e0121599. doi: 10.1371/journal.pone.0121599. eCollection 2015.

5.

The endoplasmic reticulum stress sensor IRE1α protects cells from apoptosis induced by the coronavirus infectious bronchitis virus.

Fung TS, Liao Y, Liu DX.

J Virol. 2014 Nov;88(21):12752-64. doi: 10.1128/JVI.02138-14. Epub 2014 Aug 20.

6.

Regulation of axon growth by the JIP1-AKT axis.

Dajas-Bailador F, Bantounas I, Jones EV, Whitmarsh AJ.

J Cell Sci. 2014 Jan 1;127(Pt 1):230-9. doi: 10.1242/jcs.137208. Epub 2013 Nov 6.

7.

The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex.

van den Berg MC, van Gogh IJ, Smits AM, van Triest M, Dansen TB, Visscher M, Polderman PE, Vliem MJ, Rehmann H, Burgering BM.

J Biol Chem. 2013 Jul 26;288(30):21729-41. doi: 10.1074/jbc.M113.463885. Epub 2013 Jun 14. Erratum in: J Biol Chem. 2016 Jan 15;291(3):1200.

8.

IGF-I attenuates FFA-induced activation of JNK1 phosphorylation and TNFα expression in human subcutaneous preadipocytes.

Neacsu O, Cleveland K, Xu H, Tchkonia TT, Kirkland JL, Boney CM.

Obesity (Silver Spring). 2013 Sep;21(9):1843-9. doi: 10.1002/oby.20329. Epub 2013 May 25.

9.

Histamine H3 receptor antagonists in relation to epilepsy and neurodegeneration: a systemic consideration of recent progress and perspectives.

Bhowmik M, Khanam R, Vohora D.

Br J Pharmacol. 2012 Dec;167(7):1398-414. doi: 10.1111/j.1476-5381.2012.02093.x. Review.

10.

Apigenin induces apoptosis in human leukemia cells and exhibits anti-leukemic activity in vivo.

Budhraja A, Gao N, Zhang Z, Son YO, Cheng S, Wang X, Ding S, Hitron A, Chen G, Luo J, Shi X.

Mol Cancer Ther. 2012 Jan;11(1):132-42. doi: 10.1158/1535-7163.MCT-11-0343. Epub 2011 Nov 14.

11.

Mitochondrial regulation of cell cycle and proliferation.

Antico Arciuch VG, Elguero ME, Poderoso JJ, Carreras MC.

Antioxid Redox Signal. 2012 May 15;16(10):1150-80. doi: 10.1089/ars.2011.4085. Epub 2012 Jan 13. Review.

12.

Ursolic acid induces apoptosis in human leukaemia cells and exhibits anti-leukaemic activity in nude mice through the PKB pathway.

Gao N, Cheng S, Budhraja A, Gao Z, Chen J, Liu EH, Huang C, Chen D, Yang Z, Liu Q, Li P, Shi X, Zhang Z.

Br J Pharmacol. 2012 Mar;165(6):1813-1826. doi: 10.1111/j.1476-5381.2011.01684.x.

13.

Blocking Epidermal Growth Factor Receptor Signaling in HTR-8/SVneo First Trimester Trophoblast Cells Results in Dephosphorylation of PKBα/AKT and Induces Apoptosis.

Bolnick J, Albitar L, Laidler LL, Abdullah R, Leslie KK.

Obstet Gynecol Int. 2011;2011:896896. doi: 10.1155/2011/896896. Epub 2011 Aug 21.

14.

Gq protein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun N-terminal kinase activation.

Ben-Ami I, Yao Z, Naor Z, Seger R.

J Biol Chem. 2011 Sep 2;286(35):31022-31. doi: 10.1074/jbc.M111.247726. Epub 2011 Jul 13. Retraction in: J Biol Chem. 2017 May 26;292(21):8848.

15.

Phenethyl isothiocyanate exhibits antileukemic activity in vitro and in vivo by inactivation of Akt and activation of JNK pathways.

Gao N, Budhraja A, Cheng S, Liu EH, Chen J, Yang Z, Chen D, Zhang Z, Shi X.

Cell Death Dis. 2011 Apr 7;2:e140. doi: 10.1038/cddis.2011.22.

16.

Glial cell line-derived neurotrophic factor receptor-α1 expressed in striatum in trans regulates development and injury response of dopamine neurons of the substantia nigra.

Kholodilov N, Kim SR, Yarygina O, Kareva T, Cho JW, Baohan A, Burke RE.

J Neurochem. 2011 Feb;116(4):486-98. doi: 10.1111/j.1471-4159.2010.07128.x. Epub 2011 Jan 19.

17.

Requirement of JIP1-mediated c-Jun N-terminal kinase activation for obesity-induced insulin resistance.

Morel C, Standen CL, Jung DY, Gray S, Ong H, Flavell RA, Kim JK, Davis RJ.

Mol Cell Biol. 2010 Oct;30(19):4616-25. doi: 10.1128/MCB.00585-10. Epub 2010 Aug 2.

18.

Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-beta after vascular damage.

Schachtrup C, Ryu JK, Helmrick MJ, Vagena E, Galanakis DK, Degen JL, Margolis RU, Akassoglou K.

J Neurosci. 2010 Apr 28;30(17):5843-54. doi: 10.1523/JNEUROSCI.0137-10.2010.

19.

Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features.

Han I, You Y, Kordower JH, Brady ST, Morfini GA.

J Neurochem. 2010 Jun;113(5):1073-91. doi: 10.1111/j.1471-4159.2010.06672.x. Epub 2010 Mar 17. Review.

20.

Melatonin Induces Akt Phosphorylation through Melatonin Receptor- and PI3K-Dependent Pathways in Primary Astrocytes.

Kong PJ, Byun JS, Lim SY, Lee JJ, Hong SJ, Kwon KJ, Kim SS.

Korean J Physiol Pharmacol. 2008 Apr;12(2):37-41. doi: 10.4196/kjpp.2008.12.2.37. Epub 2008 Apr 30.

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