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Items: 17


Role of phosphatidylinositol-4,5-bisphosphate 3-kinase signaling in vesicular trafficking.

Bhattacharya S, McElhanon KE, Gushchina LV, Weisleder N.

Life Sci. 2016 Dec 15;167:39-45. doi: 10.1016/j.lfs.2016.10.018. Epub 2016 Oct 17. Review.


Activity of Pan-Class I Isoform PI3K/mTOR Inhibitor PF-05212384 in Combination with Crizotinib in Ovarian Cancer Xenografts and PDX.

Iezzi A, Caiola E, Broggini M.

Transl Oncol. 2016 Oct;9(5):458-465. doi: 10.1016/j.tranon.2016.08.011.


Protein Kinases as Drug Development Targets for Heart Disease Therapy.

Dhalla NS, Müller AL.

Pharmaceuticals (Basel). 2010 Jul 5;3(7):2111-2145. Review.


Evolutionary history of phosphatidylinositol- 3-kinases: ancestral origin in eukaryotes and complex duplication patterns.

Philippon H, Brochier-Armanet C, Perrière G.

BMC Evol Biol. 2015 Oct 19;15:226. doi: 10.1186/s12862-015-0498-7.


A novel protein kinase-like domain in a selenoprotein, widespread in the tree of life.

Dudkiewicz M, Szczepińska T, Grynberg M, Pawłowski K.

PLoS One. 2012;7(2):e32138. doi: 10.1371/journal.pone.0032138. Epub 2012 Feb 16.


RAS Interaction with PI3K: More Than Just Another Effector Pathway.

Castellano E, Downward J.

Genes Cancer. 2011 Mar;2(3):261-74. doi: 10.1177/1947601911408079.


Light-induced tyrosine phosphorylation of rod outer segment membrane proteins regulate the translocation, membrane binding and activation of type II α phosphatidylinositol-5-phosphate 4-kinase.

Huang Z, Anderson RE, Cao W, Wiechmann AF, Rajala RV.

Neurochem Res. 2011 Apr;36(4):627-35. doi: 10.1007/s11064-010-0146-y. Epub 2010 Mar 5.


Crystal structures of PI3K-C2alpha PX domain indicate conformational change associated with ligand binding.

Parkinson GN, Vines D, Driscoll PC, Djordjevic S.

BMC Struct Biol. 2008 Feb 29;8:13. doi: 10.1186/1472-6807-8-13.


Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphatase.

Mason D, Mallo GV, Terebiznik MR, Payrastre B, Finlay BB, Brumell JH, Rameh L, Grinstein S.

J Gen Physiol. 2007 Apr;129(4):267-83.


Transcriptional analysis of three major putative phosphatidylinositol kinase genes in a parasitic protozoan, Giardia lamblia.

Hernandez Y, Zamora G, Ray S, Chapoy J, Chavez E, Valvarde R, Williams E, Aley SB, Das S.

J Eukaryot Microbiol. 2007 Jan-Feb;54(1):29-32.


MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics.

Davis CN, Mann E, Behrens MM, Gaidarova S, Rebek M, Rebek J Jr, Bartfai T.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2953-8. Epub 2006 Feb 13.


Specific role for p85/p110beta in GTP-binding-protein-mediated activation of Akt.

Kubo H, Hazeki K, Takasuga S, Hazeki O.

Biochem J. 2005 Dec 15;392(Pt 3):607-14.


Visualisation and graph-theoretic analysis of a large-scale protein structural interactome.

Bolser D, Dafas P, Harrington R, Park J, Schroeder M.

BMC Bioinformatics. 2003 Oct 8;4:45.


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