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Items: 1 to 20 of 42


Treatment of diabetes mellitus-induced erectile dysfunction using endothelial progenitor cells genetically modified with human telomerase reverse transcriptase.

Zhang Y, Chen Z, Wang T, Yang J, Li R, Wang S, Liu J, Ye Z.

Oncotarget. 2016 Jun 28;7(26):39302-39315. doi: 10.18632/oncotarget.9909.


Sirtuins, Cell Senescence, and Vascular Aging.

Kida Y, Goligorsky MS.

Can J Cardiol. 2016 May;32(5):634-41. doi: 10.1016/j.cjca.2015.11.022. Epub 2015 Dec 8. Review.


Effects of Lifestyle Modification on Telomerase Gene Expression in Hypertensive Patients: A Pilot Trial of Stress Reduction and Health Education Programs in African Americans.

Duraimani S, Schneider RH, Randall OS, Nidich SI, Xu S, Ketete M, Rainforth MA, Gaylord-King C, Salerno JW, Fagan J.

PLoS One. 2015 Nov 16;10(11):e0142689. doi: 10.1371/journal.pone.0142689. eCollection 2015.


NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability.

Parplys AC, Zhao W, Sharma N, Groesser T, Liang F, Maranon DG, Leung SG, Grundt K, Dray E, Idate R, Østvold AC, Schild D, Sung P, Wiese C.

Nucleic Acids Res. 2015 Nov 16;43(20):9817-34. doi: 10.1093/nar/gkv859. Epub 2015 Aug 31.


Genome Wide Expression Profiling of Cancer Cell Lines Cultured in Microgravity Reveals Significant Dysregulation of Cell Cycle and MicroRNA Gene Networks.

Vidyasekar P, Shyamsunder P, Arun R, Santhakumar R, Kapadia NK, Kumar R, Verma RS.

PLoS One. 2015 Aug 21;10(8):e0135958. doi: 10.1371/journal.pone.0135958. eCollection 2015.


Donepezil attenuates high glucose-accelerated senescence in human umbilical vein endothelial cells through SIRT1 activation.

Zhang T, Tian F, Wang J, Zhou S, Dong X, Guo K, Jing J, Zhou Y, Chen Y.

Cell Stress Chaperones. 2015 Sep;20(5):787-92. doi: 10.1007/s12192-015-0601-4. Epub 2015 Jul 21.


SIRT1 suppresses the senescence-associated secretory phenotype through epigenetic gene regulation.

Hayakawa T, Iwai M, Aoki S, Takimoto K, Maruyama M, Maruyama W, Motoyama N.

PLoS One. 2015 Jan 30;10(1):e0116480. doi: 10.1371/journal.pone.0116480. eCollection 2015.


Stable cellular senescence is associated with persistent DDR activation.

Fumagalli M, Rossiello F, Mondello C, d'Adda di Fagagna F.

PLoS One. 2014 Oct 23;9(10):e110969. doi: 10.1371/journal.pone.0110969. eCollection 2014.


Opposite roles for p38MAPK-driven responses and reactive oxygen species in the persistence and resolution of radiation-induced genomic instability.

Werner E, Wang H, Doetsch PW.

PLoS One. 2014 Oct 1;9(10):e108234. doi: 10.1371/journal.pone.0108234. eCollection 2014.


Telomere Q-PNA-FISH--reliable results from stochastic signals.

Cukusic Kalajzic A, Vidacek NS, Huzak M, Ivankovic M, Rubelj I.

PLoS One. 2014 Mar 18;9(3):e92559. doi: 10.1371/journal.pone.0092559. eCollection 2014.


Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis.

Shim G, Ricoul M, Hempel WM, Azzam EI, Sabatier L.

Mutat Res Rev Mutat Res. 2014 Jan 31. pii: S1383-5742(14)00002-7. doi: 10.1016/j.mrrev.2014.01.001. [Epub ahead of print] Review.


Dickkopf-1, the Wnt antagonist, is induced by acidic pH and mediates epithelial cellular senescence in human reflux esophagitis.

Lyros O, Rafiee P, Nie L, Medda R, Jovanovic N, Schmidt J, Mackinnon A, Venu N, Shaker R.

Am J Physiol Gastrointest Liver Physiol. 2014 Apr 1;306(7):G557-74. doi: 10.1152/ajpgi.00153.2013. Epub 2014 Jan 30.


ES micro-environment enhances stemness and inhibits apoptosis in human limbal stem cells via the maintenance of telomerase activity.

Liu Z, Wan P, Duan H, Zhou J, Tan B, Liu Y, Zhou Q, Zhou C, Huang Z, Tian B, Li C, Wang Z.

PLoS One. 2013;8(1):e53576. doi: 10.1371/journal.pone.0053576. Epub 2013 Jan 11.


Functional comparison of chronological and in vitro aging: differential role of the cytoskeleton and mitochondria in mesenchymal stromal cells.

Geissler S, Textor M, Kühnisch J, Könnig D, Klein O, Ode A, Pfitzner T, Adjaye J, Kasper G, Duda GN.

PLoS One. 2012;7(12):e52700. doi: 10.1371/journal.pone.0052700. Epub 2012 Dec 28.


Telomere lengthening and other functions of telomerase.

Rubtsova MP, Vasilkova DP, Malyavko AN, Naraikina YV, Zvereva MI, Dontsova OA.

Acta Naturae. 2012 Apr;4(2):44-61.


The canonical NF-κB pathway differentially protects normal and human tumor cells from ROS-induced DNA damage.

Sfikas A, Batsi C, Tselikou E, Vartholomatos G, Monokrousos N, Pappas P, Christoforidis S, Tzavaras T, Kanavaros P, Gorgoulis VG, Marcu KB, Kolettas E.

Cell Signal. 2012 Nov;24(11):2007-23. doi: 10.1016/j.cellsig.2012.06.010. Epub 2012 Jun 29.


AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy.

Astle MV, Hannan KM, Ng PY, Lee RS, George AJ, Hsu AK, Haupt Y, Hannan RD, Pearson RB.

Oncogene. 2012 Apr 12;31(15):1949-62. doi: 10.1038/onc.2011.394. Epub 2011 Sep 12.


Transcriptional regulation of the human telomerase reverse transcriptase: new insights.

Chebel A, Ffrench M.

Transcription. 2010 Jul-Aug;1(1):27-31. doi: 10.4161/trns.1.1.12062.

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